Biodegradable iron-based alloy hemostatic clamp and preparation method thereof

Abstract

The invention relates to the technical field of medical appliances, and particularly discloses a biodegradable hemostatic clamp used for a laparoscopic operation and having an antibacterial function at the same time and a preparation method thereof. The biodegradable hemostatic clamp having the antibacterial function at the same time is characterized in that the hemostatic clamp is prepared from a biodegradable iron-based alloy, wherein the component of the iron-based alloy is pure iron of which the purity is 99.95 percent or is an Fe-Mn alloy which is prepared from 99.95 percent of pure iron and manganese through carrying out componential proportioning (ratio) according to weights. The iron-based alloy has excellent mechanism performance (high strength, high plasticity, high toughness and the like) and favorable biocompatibility and biodegradable property; a bioactive functional layer containing Ag ions is prepared on the surface of a prepared iron-based hemostatic clamp by adopting an ion injection method; the degradation rate of an alloy can be adjusted while an iron-based alloy hemostatic clamp is enabled to have a certain antibacterial function, so as to meet the clinical demands of the laparoscopic operation in different operation environments.

Description

technical field [0001] The invention belongs to the technical field of medical devices, in particular to a biodegradable iron-based alloy hemostatic clip with antibacterial function and a preparation method thereof. Background technique [0002] Hemostatic clips for laparoscopic surgery mainly include metal clips and absorbable polymer clips. Among them, metal clips include silver clips, tantalum clips and titanium clips, and the metal clips used clinically today are mainly titanium clips. At present, only Absolok ligature clips manufactured by Johnson & Johnson and Lapro-Clip absorbable ligature clips manufactured by American Tyco Corporation are the only absorbable polymer clips used in China. For metal titanium clips, although they have been widely used clinically, there are still some disadvantages: (1) "slipping" or "loosening". When the blood vessels are clamped in "parallel", the clamped edema vessels or tissues will gradually subside after the operation. After the ...

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Problems solved by technology

However, as a biodegradable hemostatic clip, magnesium alloy also has the following disadvantages: (1) Degradation rate, the degradation rate of magnesium-based alloys in physiological environment is too fast and uneven, and it is likely to lose its application when the patient is not fully recovered. Some clamping force; (2) Inflammation, the degradation products of magnesium-based alloys are alkaline, which is easy to cause inflammatory reactions; (3) Mechanical properties, the mechanical properties of magnesium-based alloys are poor in toughness, and the "U"-shaped turning of the hemostatic clip prone to cracks or breaks

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