System and method of calculating serum neutralization antibody titer

An antibody titer and serum technology, applied in the field of parameter calculation, can solve the problems of long time, heavy workload, inconvenient use, etc., and achieve the effect of short time and small workload.

Inactive Publication Date: 2017-06-06
INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The calculation and operation process is cumbersome, with heavy workload, long time use, low efficiency, and inconvenient use. It is easy to make calculation errors in the process, whi

Method used

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  • System and method of calculating serum neutralization antibody titer
  • System and method of calculating serum neutralization antibody titer
  • System and method of calculating serum neutralization antibody titer

Examples

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Comparison scheme
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Embodiment Construction

[0066] The principles and features of the present invention are described below in conjunction with the accompanying drawings, and the examples given are only used to explain the present invention, and are not intended to limit the scope of the present invention.

[0067] like figure 1 As shown, the system for calculating serum neutralizing antibody titer provided by Embodiment 1 of the present invention includes:

[0068] The input module is used to input the measured test data;

[0069] Specifically, the measured test data includes the dilution ratio, and the number of diseased wells and the number of non-pathological wells under each dilution ratio. The dilution ratio includes the dilution ratio of the virus in the test and the dilution ratio of the serum. The dilution ratio can be two Double dilution and set N dilution gradients, N is a positive integer of zero or greater than zero, the dilution ratio can also be ten-fold dilution and set N dilution gradients, N is a posi...

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Abstract

The invention relates to the field of parameter calculation, in particular to a system and method of calculating serum neutralization antibody titer. The system of calculating the serum neutralization antibody titer comprises a recording module, a calculation module, a display module and a storing module, the recording module is used for recording measured experimental data, the calculation module is used for calculating intermediate data and serum neutralization antibody titer data according to the recorded experimental data, the display module is used for displaying the recorded experimental data and the calculated intermediate data and the serum neutralization antibody titer data, and the storing module is used for storing the recorded experimental data and the calculated intermediate data and the serum neutralization antibody titer data. According to the system and method of calculating the serum neutralization antibody titer, the serum neutralization antibody titer is calculated easily, conveniently, fast and accurately, the workload is little, and all the experimental data are effectively protected and stored, and can be remained for next check and use.

Description

technical field [0001] The invention relates to the field of parameter calculation, in particular to a system and method for calculating serum neutralizing antibody titer. Background technique [0002] Studies have shown that after an animal body is infected by a virus, the body will produce antibodies. If the antibody can specifically bind to the corresponding virus particles and make the latter lose its infectivity, this antibody is called a neutralizing antibody. Neutralizing antibodies appear in the early stage of viral infection, and can reach a very high level in the late stage of acute infection. The presence and titer of neutralizing antibodies in animals can be detected by using known viruses or virus antigens. The most commonly used method is the "fixed virus-diluted serum" method, which is to combine serum with different dilution gradients with a fixed amount of virus liquid ( Generally, 100 TCID50, EID50 or LD50) are mixed, placed under appropriate conditions fo...

Claims

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Application Information

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IPC IPC(8): G06F19/00
CPCG16H10/40
Inventor 廉士珍闫喜军胡博朱言柱张蕾
Owner INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
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