16results about How to "Improve crystallization efficiency" patented technology

This invention relates to a method for improving protein crystallization efficiency using hydrogel regulation. The method includes the following steps: mixing monomers to obtain a prepolymer solution, adding water and a photoinitiator, stirring to obtain a hydrogel precursor solution; stabilizing the obtained hydrogel precursor solution, then irradiating it with ultraviolet light to obtain a rough hydrogel; immersing the rough hydrogel in water and then drying it to obtain a dried hydrogel; preparing a buffer solution and using the prepared buffer solution to prepare a precipitant; immersing the dried hydrogel obtained in the previous step in the prepared precipitant to swell the dried hydrogel, washing and drying it to obtain a target hydrogel; dissolving the protein in the prepared buffer solution to obtain a protein solution; and dropping the obtained protein solution onto the surface of the obtained target hydrogel to crystallize it to obtain protein crystals. Compared with existing technologies, this invention can effectively solve the problem of low efficiency in protein crystallization while ensuring the quality of protein crystals.

The utility model relates to a pyrrole quinolinone production technical field especially relates to a kind of recovery treatment system for pyrrole quinolinone salting-out mother liquor and crystallization mother liquor, including pyrrole quinolinone salting-out mother liquor conveying pipeline and pyrrole quinolinone crystallization mother liquor conveying pipeline, pyrrole quinolinone salting-out mother liquor conveying pipeline, first concentration kettle, first crystallization, first drying device, sodium chloride storage tank and series connection;Pyrrole quinolinone crystallization mother liquor conveying pipeline, second concentration kettle, dilution kettle, decoloring kettle, first resin column, first pH adjusting kettle, second resin column, second pH adjusting kettle, second crystallization kettle, second drying device, pyrrole quinolinone storage tank are connected in series in proper order.The above-mentioned recovery treatment system design is reasonable, can recycle and utilize sodium chloride in salting-out mother liquor and pyrrole quinolinone in crystallization mother liquor, avoids resource waste.

The utility model relates to a static crystallization separation device. The crystal collecting device comprises a scraping assembly used for scraping crystals on the crystallization assembly, and a collecting box used for collecting the crystals is installed at the lower end of the scraping assembly. After crystals are formed on fin plates of the crystallization assembly, through starting of a motor, a rotating rod drives a second bevel gear to rotate, the second bevel gear is matched with a first bevel gear to drive two reciprocating lead screws to rotate synchronously, the reciprocating lead screws are matched with lead screw nuts to drive a U-shaped plate to move front and back, and the crystals on a separation box are scraped away through a scraping plate; according to the utility model, after the crystals are scraped by the scraping plate, crystallization can be continuously carried out on the fin plate of the crystallization assembly, so that the crystallization efficiency of the fin plate is improved.

The utility model discloses a sugar cooling vertical crystallizer which comprises a vertical tank body, a top cover is arranged at the top of the tank body, a syrup inlet is formed in the top cover, a conical hopper is arranged at the bottom of the tank body, a syrup outlet is formed in the conical hopper, a plurality of heat exchange coil pipes are arranged in an inner cavity of the tank body in the height direction, each heat exchange coil pipe adopts a circular pipe distribution mode, and six concave arcs are evenly distributed on the periphery of each heat exchange coil pipe. A vertical column extending in the vertical direction is arranged in each concave arc, each heat exchange coil pipe is supported on a radial support, and the outer end of each radial support is fixedly connected to the corresponding vertical column. A lifting mechanism for driving the stand columns and the heat exchange coil to ascend and descend is arranged above the top cover. An upper stirring mechanism for uniformly distributing syrup on the cross section of the tank body is arranged above the top-layer heat exchange coil pipe, and a lower stirring mechanism is arranged in the conical hopper. The sugar cooling vertical crystallizer is high in crystallization efficiency, short in crystallization time, high in single productivity and low in operation failure rate.

The utility model discloses efficient crystallization equipment for triple superphosphate, which relates to the technical field of crystallization equipment and comprises a crystallization bin and a bottom plate, the top surface of the bottom plate is fixedly connected with a PLC (programmable logic controller) and four support rods, one ends, far away from the bottom plate, of the four support rods are fixedly connected with fixing sleeves, and the fixing sleeves are fixedly connected with the crystallization bin. A crystallization mechanism used for crystallizing triple superphosphate is arranged on the inner side of the crystallization bin, a monitoring mechanism is arranged on the surface of the crystallization bin, feed liquid circulates in the cooling pipes, cooling water is added into the crystallization bin through the cooling water inlet, and the cooling water is guided out through the cooling water outlet. Heat of the feed liquid in the cooling pipes is taken away by the cooling water in the circulation process of the cooling water, then the feed liquid is cooled, crystals are separated out while cooling is conducted, and the crystals are discharged into the collecting box at the feed liquid water outlet to be subjected to next operation, the twenty-five cooling pipes are arranged for circulation cooling of the feed liquid, and the problem that existing crystallization equipment is low in crystallization efficiency is solved.

The utility model relates to crystallization fluidized bed anti -scale technical field especially discloses a kind of water scale inhibition disturbance devices of water hardness removal crystallization fluidized bed. The water scale inhibition disturbance device of water hardness removal crystallization fluidized bed, including the spray gun pipe and water cannon pipe installed above crystallization fluidized bed by support assembly, it is characterized by: adjustable spray head is installed at the front end of the spray gun pipe, the tail end of spray gun pipe is connected the water outlet of injection branch pipe by flexible pressure hose A, the water inlet of injection branch pipe is communicated with water supply main pipe;The tail end of water cannon pipe is connected the water outlet of water cannon branch pipe by flexible pressure hose B, the water inlet of water cannon branch pipe is communicated with water supply main pipe. The utility model device is high in integration, reasonable in design, scale layer adhesion is destroyed by water conservancy disturbance to crystallization fluidized bed, avoid local supersaturation too high, effectively maintain the uniformity of fluidized bed, improve crystallization efficiency and seed activity, prolong the service life of equipment, reduce long-term operation and maintenance cost, suitable for widely popularization and application.

The utility model belongs to the technical field of chemical equipment, and particularly relates to an evaporative crystallization tank which comprises a kettle body, a feeding pipe and a pure water pipeline are arranged at the bottom of the kettle body, a preheater, an evaporative heat exchanger and a separator are sequentially connected to the lower portion of the kettle body, and the lower portion of the preheater is connected with the bottom of a steam heat exchanger. A tubular heater is arranged at the lower part of the inner side of the kettle body; a vertical stirring assembly is arranged in the kettle body, penetrates through the top of the kettle body and is connected with a motor; the upper part of the kettle body is connected with a steam pipeline; the top of the kettle body is connected with a vacuum condenser; and the vacuum condenser is connected with a vacuum pump. According to the utility model, heat exchange is carried out through secondary steam at the lower part of the kettle body, and a sugar solution is heated inside and returns to the kettle body after being circulated outside the kettle, so that the mixing degree of the sugar solution and the contact area between the sugar solution and air can be increased.

The utility model relates to the technical field of production of creatine pyruvate, in particular to a crystallization device for creatine pyruvate. The upper side wall of the crystallization kettle is fixedly installed with a kettle cover, and the top of the kettle cover is fixedly connected with two feed pipes in a symmetrical manner. When the upper end of the top block is in contact with the side wall of the embedded groove, the baffle blocks the leakage hole, the crystal seeds can be put into and temporarily stored in the inside of the storage cylinder through the feed pipe, when feeding is needed, the motor drives the stirring rod to rotate slowly, the stirring rod drives the two storage cylinders to rotate synchronously, the side wall of the embedded groove and the chamfer push the top block downward, the top block drives the baffle to move downward synchronously through the extension rod, when the top block completely slides out of the embedded groove and is in contact with the lower side wall of the positioning ring, the baffle moves downward to below the leakage hole, the crystal seeds in the storage cylinder fall into the solution evenly under the action of gravity through the opened leakage hole, so that the uniform scattering of the crystal seeds in the solution is realized, and the crystallization efficiency and product quality are improved.

This utility model discloses a cold-side jacket structure and a paraxylene crystallizer. The cold-side jacket structure includes an annular tube, a delivery tube, an inlet tube, and an outlet tube. Two annular tubes are arranged vertically at intervals. Multiple delivery tubes are arranged between two annular tubes and along the circumference of the annular tubes, with each delivery tube connected to two annular tubes at both ends. The inlet tube is connected to the lower annular tube and has a first porous component inside. The outlet tube is connected to the upper annular tube and has a second porous component inside. The cold-side jacket structure provided by this application solves the problem of uneven distribution of refrigerant fluid during flow within multiple delivery tubes.

This utility model discloses an energy-saving low-temperature desalination and dehydration device, relating to the technical field of desalination and dehydration equipment. It includes a vacuum evaporator and a feed inlet: the feed inlet is located above the vacuum evaporator. After the concentrated water discharged from the membrane separation component of this energy-saving low-temperature desalination and dehydration device enters the crystallization reactor, a second motor drives the drive shaft to rotate, causing the wall-scraping agitator to operate continuously within the crystallization reactor. This agitation promotes uniform crystallization of salts in the solution, preventing disordered crystal growth due to localized supersaturation, thus improving crystallization efficiency and purity. Furthermore, the outer end of the wall-scraping agitator moves closely against the inner wall of the crystallization reactor, effectively preventing crystals from adhering to the reactor wall and forming scale, thus avoiding impact on the reactor's heat transfer efficiency and subsequent cleaning difficulty. This ensures uniform solid-liquid distribution of the mixed liquid entering the centrifugal separator, providing favorable conditions for subsequent solid-liquid separation, thereby guaranteeing the efficient and stable operation of the entire desalination and dehydration process.

The utility model discloses a nickel chloride cooling crystallization device and relates to the technical field of nickel chloride cooling crystallization. The nickel chloride cooling crystallization device comprises a supporting base, the upper surface of the supporting base is fixedly connected with a plurality of connecting rods, the upper ends of the connecting rods are fixedly connected with a reaction tank, the outer surface of the reaction tank is fixedly connected with a liquid outlet pipe, the liquid outlet pipe is communicated with the interior of the reaction tank, and the reaction tank is provided with a crystallization mechanism. The scraping ring moves upwards to scrape crystals on the inner wall of the reaction tank into the collecting ring frame, the filter screen moves upwards to fish out the crystals upwards, then solid-liquid separation is achieved, liquid can be discharged out of the reaction tank through the liquid outlet pipe, then solid-liquid separation of nickel chloride can be achieved through the scheme, solid-liquid separation is efficient, solid-liquid separation is simple and flexible, and operation is easy and convenient. Therefore, the practicability of the nickel chloride cooling crystallization device is improved.

The utility model discloses a quick-setting crystallizer which comprises an outer cylinder body, a spiral flow deflector is arranged between the outer cylinder body and an inner cylinder body, a cooling interlayer is fixedly installed on the inner side of the inner cylinder body, the upper end of the outer side of a shaft rod is fixedly connected with a push type stirring blade, and the lower end of the outer side of the shaft rod is fixedly connected with an anchor type stirring blade. The bottom end of the shaft rod is fixedly connected with a flow guide cone, feed liquid enters from a top feed port, a cooling medium is reversely introduced into each interlayer from top to middle to bottom, cooling water spirally moves through spiral flow deflectors, and the heat exchange coefficient is increased by more than 40%; crystal mush is guided by the flow guide cone to form secondary circulation, full-volume mixing is realized by matching with the double-structure stirring blades, and a temperature gradient of 10-25 DEG C / m is established through segmented temperature control, so that ordered growth of crystals is promoted; according to the device, the rotating speed of the shaft rod is controlled through the servo motor, the flowing speed of materials is adjusted, and the materials can be uniformly mixed, so that the cooling efficiency can be improved, the crystallization efficiency is improved, and the energy consumption is reduced.

The utility model discloses a pesticide fluorination reaction crystallization device which comprises a reaction kettle body, a shell is arranged on the outer wall of the reaction kettle body, an ultrasonic generator is installed on one side of the circumferential outer wall of the shell, transducers are arranged at the bottom of the reaction kettle body in an annular array mode, and the ultrasonic generator is installed on one side of the circumferential outer wall of the shell. The reaction kettle body is provided with a stirring assembly used for stirring materials in the reaction kettle body, a feeding assembly used for feeding seed crystals into the reaction kettle body, and a driving assembly used for driving the stirring assembly and the feeding assembly. According to the reaction kettle, fine crystal nucleuses can be broken, excessive crystal nucleuses in the reaction kettle body can be reduced, so that the crystals grow more uniformly, the mass transfer efficiency is enhanced, the cooling process is more uniform, the phenomenon of local supercooling and superheating is avoided, stable growth of the crystals is facilitated, and the crystals are promoted to grow to a larger particle size; and subsequent solid-liquid separation and screening are facilitated.

The utility model discloses a kind of citric acid concentration evaporation crystallization drying devices, including citric acid pre-concentration tank, the inlet of citric acid pre-concentration tank is connected with the outlet of pre-concentration three-effect discharge pump, the outlet of citric acid pre-concentration tank is connected with the top feed inlet of one effect falling film evaporator by citric acid pre-concentration feed pump;Steam pipeline is connected with the inlet of steam jet pump by regulating valve, the outlet of steam jet pump is connected with the shell side inlet of one effect falling film evaporator;The lower portion of one effect falling film evaporator is communicated with one effect separator, and the bottom outlet of both is jointly connected the inlet of one effect discharge pump;The outlet of one effect discharge pump is connected with the top feed inlet of two effect falling film evaporator;The top outlet of one effect separator is connected with the suction port of steam jet pump and the shell side inlet of two effect falling film evaporator simultaneously.The device can improve product crystallization efficiency, shorten production cycle;Crystalline granularity is more uniform, high purity, and steam consumption is lower.

The invention belongs to the technical field of biological fermentation and crystallization separation, discloses a method and a system for producing isomaltulose by coupling double-bacterium synergistic fermentation with gradient temperature control crystallization, and solves the problem that glucose generates feedback inhibition on sucrose isomerase in a fermentation stage. The method comprises a fermentation stage and a crystallization stage, a double-bacterium synergistic fermentation system of recombinant bacillus subtilis engineering bacteria and recombinant pichia pastoris engineering bacteria is adopted in the fermentation stage, and the inoculation ratio of the recombinant bacillus subtilis engineering bacteria to the recombinant pichia pastoris engineering bacteria is 3: 1-5: 1; in the crystallization stage, a gradient temperature control-ultrasonic-assisted coupling crystallization process is adopted, after the fermentation liquor is subjected to concentration pretreatment, the temperature is reduced to 25-28 DEG C at the speed of 0.5-0.8 DEG C / h, and heat preservation and ultrasonic treatment are performed; and cooling to 15-18 DEG C at the speed of 0.3-0.5 DEG C / h, preserving heat and carrying out ultrasonic treatment. The method provided by the invention realizes efficient production and accurate purification of isomaltulose.