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7results about How to "Improve crystallization efficiency" patented technology

Method for improving protein crystallization efficiency by using hydrogel

ActiveCN115260281BImprove crystallization efficiencyquality improvementPeptide preparation methods
This invention relates to a method for improving protein crystallization efficiency using hydrogel regulation. The method includes the following steps: mixing monomers to obtain a prepolymer solution, adding water and a photoinitiator, stirring to obtain a hydrogel precursor solution; stabilizing the obtained hydrogel precursor solution, then irradiating it with ultraviolet light to obtain a rough hydrogel; immersing the rough hydrogel in water and then drying it to obtain a dried hydrogel; preparing a buffer solution and using the prepared buffer solution to prepare a precipitant; immersing the dried hydrogel obtained in the previous step in the prepared precipitant to swell the dried hydrogel, washing and drying it to obtain a target hydrogel; dissolving the protein in the prepared buffer solution to obtain a protein solution; and dropping the obtained protein solution onto the surface of the obtained target hydrogel to crystallize it to obtain protein crystals. Compared with existing technologies, this invention can effectively solve the problem of low efficiency in protein crystallization while ensuring the quality of protein crystals.
Owner:EAST CHINA UNIV OF SCI & TECH

A recovery treatment system for pyrroloquinoline quinone salted mother liquor and crystallized mother liquor

ActiveCN224404421Ureasonable designavoid wastingPyrrovinyquiniumQuinoline
The utility model relates to a pyrrole quinolinone production technical field especially relates to a kind of recovery treatment system for pyrrole quinolinone salting-out mother liquor and crystallization mother liquor, including pyrrole quinolinone salting-out mother liquor conveying pipeline and pyrrole quinolinone crystallization mother liquor conveying pipeline, pyrrole quinolinone salting-out mother liquor conveying pipeline, first concentration kettle, first crystallization, first drying device, sodium chloride storage tank and series connection;Pyrrole quinolinone crystallization mother liquor conveying pipeline, second concentration kettle, dilution kettle, decoloring kettle, first resin column, first pH adjusting kettle, second resin column, second pH adjusting kettle, second crystallization kettle, second drying device, pyrrole quinolinone storage tank are connected in series in proper order.The above-mentioned recovery treatment system design is reasonable, can recycle and utilize sodium chloride in salting-out mother liquor and pyrrole quinolinone in crystallization mother liquor, avoids resource waste.
Owner:ZHUCHENG HAOTIAN PHARMA CO LTD

Sugar cooling vertical crystallizer

ActiveCN224280312Uevenly distributedReduce the risk of water leakageSugar crystallisationThermodynamicsSugar
The utility model discloses a sugar cooling vertical crystallizer which comprises a vertical tank body, a top cover is arranged at the top of the tank body, a syrup inlet is formed in the top cover, a conical hopper is arranged at the bottom of the tank body, a syrup outlet is formed in the conical hopper, a plurality of heat exchange coil pipes are arranged in an inner cavity of the tank body in the height direction, each heat exchange coil pipe adopts a circular pipe distribution mode, and six concave arcs are evenly distributed on the periphery of each heat exchange coil pipe. A vertical column extending in the vertical direction is arranged in each concave arc, each heat exchange coil pipe is supported on a radial support, and the outer end of each radial support is fixedly connected to the corresponding vertical column. A lifting mechanism for driving the stand columns and the heat exchange coil to ascend and descend is arranged above the top cover. An upper stirring mechanism for uniformly distributing syrup on the cross section of the tank body is arranged above the top-layer heat exchange coil pipe, and a lower stirring mechanism is arranged in the conical hopper. The sugar cooling vertical crystallizer is high in crystallization efficiency, short in crystallization time, high in single productivity and low in operation failure rate.
Owner:MYANDE GRP CO LTD

Anti-fouling disturbance device for water softening crystallization fluidized bed

The utility model relates to crystallization fluidized bed anti -scale technical field especially discloses a kind of water scale inhibition disturbance devices of water hardness removal crystallization fluidized bed. The water scale inhibition disturbance device of water hardness removal crystallization fluidized bed, including the spray gun pipe and water cannon pipe installed above crystallization fluidized bed by support assembly, it is characterized by: adjustable spray head is installed at the front end of the spray gun pipe, the tail end of spray gun pipe is connected the water outlet of injection branch pipe by flexible pressure hose A, the water inlet of injection branch pipe is communicated with water supply main pipe;The tail end of water cannon pipe is connected the water outlet of water cannon branch pipe by flexible pressure hose B, the water inlet of water cannon branch pipe is communicated with water supply main pipe. The utility model device is high in integration, reasonable in design, scale layer adhesion is destroyed by water conservancy disturbance to crystallization fluidized bed, avoid local supersaturation too high, effectively maintain the uniformity of fluidized bed, improve crystallization efficiency and seed activity, prolong the service life of equipment, reduce long-term operation and maintenance cost, suitable for widely popularization and application.
Owner:JINAN TURUIDA ENVIRONMENTAL PROTECTION TECHNOLOGY CO LTD

A crystallization apparatus for pyruvate creatine

ActiveCN224474726USpread evenlyImprove crystallization efficiencyAcide pyruviqueElectric machinery
The utility model relates to the technical field of production of creatine pyruvate, in particular to a crystallization device for creatine pyruvate. The upper side wall of the crystallization kettle is fixedly installed with a kettle cover, and the top of the kettle cover is fixedly connected with two feed pipes in a symmetrical manner. When the upper end of the top block is in contact with the side wall of the embedded groove, the baffle blocks the leakage hole, the crystal seeds can be put into and temporarily stored in the inside of the storage cylinder through the feed pipe, when feeding is needed, the motor drives the stirring rod to rotate slowly, the stirring rod drives the two storage cylinders to rotate synchronously, the side wall of the embedded groove and the chamfer push the top block downward, the top block drives the baffle to move downward synchronously through the extension rod, when the top block completely slides out of the embedded groove and is in contact with the lower side wall of the positioning ring, the baffle moves downward to below the leakage hole, the crystal seeds in the storage cylinder fall into the solution evenly under the action of gravity through the opened leakage hole, so that the uniform scattering of the crystal seeds in the solution is realized, and the crystallization efficiency and product quality are improved.
Owner:SHANGHAI JINLI CHEM CO LTD

An energy-saving low-temperature desalination and dehydration device

ActiveCN224279999UAvoid affecting heat transfer efficiencyAvoid affecting difficultyWater/sewage treatment by centrifugal separationGeneral water supply conservationChemical physicsDesalination
This utility model discloses an energy-saving low-temperature desalination and dehydration device, relating to the technical field of desalination and dehydration equipment. It includes a vacuum evaporator and a feed inlet: the feed inlet is located above the vacuum evaporator. After the concentrated water discharged from the membrane separation component of this energy-saving low-temperature desalination and dehydration device enters the crystallization reactor, a second motor drives the drive shaft to rotate, causing the wall-scraping agitator to operate continuously within the crystallization reactor. This agitation promotes uniform crystallization of salts in the solution, preventing disordered crystal growth due to localized supersaturation, thus improving crystallization efficiency and purity. Furthermore, the outer end of the wall-scraping agitator moves closely against the inner wall of the crystallization reactor, effectively preventing crystals from adhering to the reactor wall and forming scale, thus avoiding impact on the reactor's heat transfer efficiency and subsequent cleaning difficulty. This ensures uniform solid-liquid distribution of the mixed liquid entering the centrifugal separator, providing favorable conditions for subsequent solid-liquid separation, thereby guaranteeing the efficient and stable operation of the entire desalination and dehydration process.
Owner:ZHANGYE JIN CHANG SOURCE COAL IND CO LTD