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Production technology of lactitol

A production process, the technology of lactitol, applied in the field of production process of functional sugar alcohol, can solve problems such as complex process, achieve the effect of increasing crystallization yield, increasing crystallization efficiency and crystal yield, and reducing production cost

Active Publication Date: 2020-02-21
FUTASTE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The primary crystallization yield of lactitol in this process is 42.5% to 48%, and the secondary crystallization needs to be purified by simulated moving bed chromatography, and the process is complex

Method used

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  • Production technology of lactitol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Add 12000.0 grams of lactose into deionized water to form a lactose solution with a concentration of 25.0% by mass, with a purity of 99.0%, adjust the pH to 8.0, add a ruthenium carbon catalyst with 2% lactose mass, set the hydrogenation temperature to 110°C, and the hydrogen pressure to 8.0 MPa, reacted for 3.0 hours to obtain a lactose hydrogenation solution, filtered to remove the catalyst to obtain a lactitol solution, collected the catalyst and reused it, the index of the lactitol solution was: mass percentage concentration 26.5%, lactitol purity 92.9%, lactose residual 4.8% , Conductivity 186.0μs / cm, transmittance 95.0%.

[0036] Ion-exchange the lactitol solution through a mixed bed at a speed of 2BV to obtain a lactitol purification solution, the indicators are: mass percentage concentration 23.0%, lactitol purity 93.5%, electrical conductivity 10.5μs / cm, and light transmission 99.9%.

[0037] Primary crystallization: the lactitol solution is concentrated to a m...

Embodiment 2

[0043] Add 12000.0 grams of lactose into deionized water to make a lactose solution with a mass percentage concentration of 45.0%, adjust the pH to 8.5, add a ruthenium carbon catalyst with 8% lactose mass, set the hydrogenation temperature to 120°C, hydrogen pressure to 10.0MPa, and react at 2.0 h, to obtain a lactose hydrogenation solution, filter and remove the catalyst to obtain a lactitol solution, collect the catalyst and reuse it, the index of the lactitol solution is: mass percentage concentration 48.0%, lactitol purity 98.7%, lactose residual 0.1%, electrical conductivity 123.0 μs / cm, transmittance 99.0%.

[0044] The lactitol solution was ion-exchanged through the mixed bed at a speed of 4BV to obtain a lactitol purification solution. The indicators were: mass percentage concentration 41.0%, lactitol purity 99.1%, electrical conductivity 4.68 μs / cm, and light transmission 100%.

[0045] Primary crystallization: the lactitol solution is concentrated to a mass percenta...

Embodiment 3

[0050] Add 12000.0 grams of lactose into deionized water to form a lactose solution with a concentration of 40.0% by mass, adjust the pH to 9.5, add a Raney nickel catalyst with 6% lactose mass, set the hydrogenation temperature to 115°C, and the hydrogen pressure to 9.0MPa. After 1.5 hours, the lactose hydrogenation solution was obtained, and the catalyst was removed by filtration after sedimentation to obtain a lactitol solution. The catalyst was collected and reused. The indicators of the lactitol solution were: mass percentage concentration 43.0%, lactitol purity 98.5%, electrical conductivity 126.0μs / cm, light transmittance 98.9%.

[0051] The lactitol solution was ion-exchanged through the mixed bed at a speed of 3BV to obtain a lactitol purification solution. The indicators were: mass percentage concentration of 38.0%, lactitol purity of 99.1%, electrical conductivity of 5.3μs / cm, and light transmission of 100%.

[0052] Primary crystallization: the lactitol solution i...

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Abstract

The present invention discloses a production technology of lactitol. Lactose is added into deionized water to prepare a lactose solution, pH is adjusted, a certain amount of a catalyst is added, a hydrogenation reaction is conducted under high temperature and high pressure to obtain a lactose hydrogenation solution, after the catalyst is removed, a lactitol solution is obtained, the lactitol solution is then purified, and concentration, crystallization and drying are conducted to obtain lactitol crystals. A primary crystallization yield of the lactitol relative to the lactose raw material reaches 55.0%-68.0% and a total yield of the lactitol relative to the lactose raw material reaches 92.2%-96.5%. At the same time, the technology is simplified in processes, liable for production and operation and also relatively low in production cost.

Description

technical field [0001] The invention relates to a production process of functional sugar alcohol, in particular to a production process of lactitol. Background technique [0002] Lactitol, also known as lactitol, chemical name 4-O-β-D-galactopyranose ~ D-sorbitol. There are two main forms of crystalline lactitol: lactitol dihydrate and lactitol monohydrate, of which lactitol monohydrate is more stable, with a melting point of 90°C to 105°C, and is the main form of lactitol. [0003] The main application of lactitol: (1) An excellent healthy sweetener and prebiotic. Lactitol is mainly produced from lactose in milk. It is natural and healthy. Its sweetness is similar to that of sucrose, with a sweetness of 30% to 40% of that of sucrose. It is refreshing and has no peculiar smell. It is non-carious and can be used in candy, chocolate, jam, jelly, table sweetening, etc. Lactitol can efficiently proliferate intestinal probiotics, regulate intestinal health, and can be used in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H1/00C07H1/06C07H15/04
CPCC07H1/00C07H1/06C07H15/04
Inventor 孙鲁黄伟红董铭周娟邢庆伟郭亚茹王运刚杜瑞锋曹玉华
Owner FUTASTE PHARM CO LTD
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