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99 results about "Triazole antifungals" patented technology
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The triazole antifungal drugs include fluconazole, isavuconazole, itraconazole, voriconazole, pramiconazole, ravuconazole, and posaconazole. The triazole plant protection fungicides include epoxiconazole, triadimenol (de), propiconazole, prothioconazole, metconazole, cyproconazole, tebuconazole, flusilazole and paclobutrazol.
Triazole compounds that modulate Hsp90 activity
ActiveUS20060167070A1Reduced growth rateInhibit tumor growthBiocideOrganic chemistryTriazole antifungalsHSP90 Heat-Shock Proteins
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Owner:SYNTA PHARMA CORP
Coating composition and article coated therewith
InactiveUS20050215670A1Improve corrosion resistancePlastic/resin/waxes insulatorsAnti-corrosive paintsEpoxyTriazole antifungals
A coating composition used for coating of a steel material and / or aluminum material comprises a corrosion inhibitor, a base resin and a curing agent. The corrosion inhibitor may be selected from cerium compounds, lanthanum compounds, molybdate salt compounds, gluconic acid derivative salts, porous base materials, triazole compounds, thiazole compounds, tetracyclines, and metal phosphate salt compounds of ascorbic acid. The base resin may include a xylene-formaldehyde-resin-modified amino-containing epoxy resins obtained by reacting an epoxy resin having an epoxy equivalent of from 180 to 2500 with a xylene formaldehyde resin and an amino-containing compound. The curing agent may be a blocked polyisocyanate compound obtained by blocking an isocyanate group of a polyisocyanate compound with a blocking agent.
Owner:KANSAI PAINT CO LTD
Triazole compounds that modulate HSP90 activity
ActiveUS20080090887A1Less developmentAntibacterial agentsBiocideTriazole antifungalsHSP90 Heat-Shock Proteins
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Owner:SYNTA PHARMA CORP
Etching solution, method of etching and printed wiring board
ActiveUS20060199394A1Efficient processEfficient coatingInsulating substrate metal adhesion improvementDecorative surface effectsTriazole antifungalsHigh concentration
There is provided an etching solution comprised of a cupric chloride solution and a high-concentration triazole type compound added to the cupric chloride solution and capable of forming an etching-inhibiting coating. In a process of forming a circuit pattern by etching with the etching solution, an etching-inhibiting coating is selected formed on parts of a copper foil laid under the edge of an etching resist to effectively inhibit horizontal side-etching of the copper foil from the edge of the etching resist. Also, nonuniform irregularities formed on the side wall of the circuit pattern by the etching improves the adhesion between the circuit pattern and an insulating resin layer covering the circuit pattern.
Owner:IBIDEN CO LTD
Pharmaceutical formulation
Disclosed are novel formulations for the treatment of otic infections in an animal comprising a triazole anti-fungal compound, a quinolone antibiotic and a corticosteroid such as mometasone furoate monohydrate.
Owner:SCHERING PLOUGH LTD +2
Corrosion protection for lubricants
InactiveUS20060240998A1Corrosion protection is enhancedAvoid corrosionLiquid carbonaceous fuelsAdditivesTriazole antifungalsThiadiazoles
The present invention relates to compositions comprising at least one triazole-containing species and at least one thiadiazole-containing species, which in embodiments are suitable for manual transmission oils.
Owner:EXXONMOBIL CHEM PAT INC
Triazole compounds that modulate HSP90 activity
ActiveUS20070155809A1Less developmentBiocideOrganic chemistryTriazole antifungalsHSP90 Heat-Shock Proteins
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Owner:SYNTA PHARMA CORP
Water soluble prodrugs of azole compounds
Owner:EISIA R&D MANAGEMENT CO LTD
Gas generant and manufacturing method thereof
InactiveUS20050257866A1Improve solubilityPromote aggregationExplosive working-up apparatusPressure gas generationTriazole antifungalsTetrazole
The present invention generally relates to gas generant compositions for inflators of occupant restraint systems, for example. An extrudable pyrotechnic composition includes polyvinylazoles for use within an airbag gas generator. The fuel may be selected from exemplary polyvinylazoles including 5-amino-1-vinyltetrazole, poly(5-vinyltetrazole), poly(2-methyl-5-vinyl) tetrazole, poly(1-vinyl) tetrazole, poly(3-vinyl) 1,2,5 oxadiazole, and poly(3-vinyl) 1,2,4-triazole. An oxidizer is combined with the fuel and preferably contains phase stabilized ammonium nitrate. A novel method of forming the compositions is also presented wherein the various constituents are wetted and / or dissolved, and then cured within the polyvinylazole matrix thereby forming a more intimate combination within the gas generant composition. A vehicle occupant protection system 180, and other gas generating systems, incorporate the compositions of the present invention.
Owner:AUTOMOTIVE SYST LAB
Triazole-derived kinase inhibitors and uses thereof
Described herein are compounds that are useful as protein kinase inhibitors having the formula: where Ht, R2, T, and m are as described in the specification. The compounds are useful for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
Owner:HALE MICHAEL R +1
Biodefenses using triazole-containing macrolides
Use of macrolide and ketolide antibiotics for the treatment of acute exposure and diseases caused by biodefense pathogens is described.
Owner:TETARD INC
Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof
ActiveUS20140343285A1Extended reaction timeLow yieldOrganic compound preparationOrganic chemistry methodsTriazole antifungalsAntifungal
Owner:MSN LAB PTE LTD
Pesticide composite containing pyraclostrobin
InactiveCN102177912ABoth protectiveBoth therapeuticBiocideFungicidesTriazole antifungalsPhytophthora sp.
The invention discloses a pesticide composite containing pyraclostrobin. The pesticide composite contains active ingredients, namely pyraclostrobin and one of triazole compounds: flusilazole, epoxiconazole, tetraconazole, tricyclazole and propiconazole. The ratio of the parts of the two active ingredients by weight is 60 to 1-1 to 60. The pesticide composite at least contains one type of surfactant, thus being beneficial to the dispersion of the active ingredients in water. The pesticide composite integrates protection activity, treatment activity with eradication activity. The pesticide composite can be used for various crop plants such as wheat, paddy rice, vegetables, fruit trees and the like; and the pesticide composite can prevent and treat diseases such as downy mildew, phytophthora disease, rust disease, powdery mildew, alternaria mali roberts, leaf spot, scab disease, rice blast and the like.
Owner:陕西汤普森生物科技有限公司
Heterocycle grafted monomers and related polymers and hybrid inorganic-organic polymer membranes
ActiveUS20060111530A1Improve proton conductivitySolution value is not highGroup 4/14 element organic compoundsSolid electrolytesTriazole antifungalsPolymer science
Polymers, polymer precursors, and other materials are described, having at least one heterocycle and being useful for fabrication of proton-exchange membranes (PEMs). In representative examples, the heterocycle is a fluorinated imidazole ring. The heterocycle can be chosen to have a low value of pKa, and may be a triazole ring, other nitrogen-containing heterocycle, or derivative thereof. Polymers and composites were prepared having excellent proton conductivity. Applications of these materials include fuel cells and other ion-conducting applications.
Owner:GEORGIA INSTITUTE OF TECHNOLOGY +1
Corrosion inhibiting compositions and methods for fuel cell coolant systems
InactiveUS20050051754A1Low conductivityImprove conductivityOther chemical processesDomestic cooling apparatusTriazole antifungalsDepressant
Carboxylic acids or the salts thereof are suitable for use in cooling systems where low electrical conductivity is required. The compositions are of particular use in fuel cell stacks. The preferred salts are those of amines. The salts can be used with a liquid alcohol freezing point depressant such as monoethylene glycol. Thiazoles and / or triazoles may be included, as well as other corrosion inhibitors known in the art.
Owner:ARTECO NV
Bacteriocidal composition containing Boscalid and triazole bactericide
ActiveCN102428931AGood synergyImprove the bactericidal effectBiocideFungicidesEpoxiconazoleTriazole antifungals
The invention relates to a bacteriocidal composition and an application thereof. The bacteriocidal composition is characterized by comprising Boscalid (A) and at least one (B) selected from the following active components of a triazole bactericide: difenoconazole, propiconazole, tebuconazole, hexaconazole, flutriafol, epoxiconazole, tetraconazole, flusilazole, myclobutanil, cyproconazole, triazolone and diniconazole, wherein the mass ratio of A to B is (1:50)-(50:1). The composition can be applied to preventing and treating diseases of crops such as cereal crops, melons, fruits, vegetables and the like.
Owner:JIANGYIN SULI CHEM
Additive system for lubricants
ActiveUS20060229214A1Improved lubricant compositionSimple compositionAdditivesTriazole antifungalsBearing wear
The invention relates to compositions suitable as additive packages for lubricants and other functional fluids, the composition comprising sulfur-containing extreme pressure components, phosphorus-containing anti-wear additives, a triazole-containing species. A preferred use is in industrial gear oils. In embodiments, enhance protection in the areas of bearing wear and micropitting are obtained.
Owner:THE LUBRIZOL CORP
Bacteriocidal composition containing boscalid and triazole compounds
InactiveCN102217604AGood synergyImprove efficiencyBiocideFungicidesTriazole antifungalsElsinoë ampelina
The invention relates to a bacteriocidal composition containing boscalid and triazole compounds, comprising an active component A and an active component B, wherein, the active component A is selected from boscalid, the active component B is selected from one of imibenconazole, triticonazole, ipconazole or fenbuconazole, and the weight ratio of the active component A to B is 1-80%:1-60%. The composition of the present invention can be prepared into dosage forms, such as wettable powder, water dispersible granule, suspending agent, suspended emulsion, suspending seed coating agent, emulsion in water or micron emulsion, by adding auxiliary agents and excipients into the active components, used for controlling powdery mildew, botrytis, net blotch, rice blast, elsinoe ampelina, septoria nodorum, rust, anthracnose, root rot, rot disease, brown rot, apple scab, leaf spot, epidemic disease, black rot, brown spot, scab and leaf rust, with effects of little chemical consumption, anti-rain wash and obvious synergistic action.
Owner:陕西汤普森生物科技有限公司
Compounds for the Treatment of Inflammation of the Central Nervous System
KATP channel openers (KCOs) are useful for the prophylactic and / or therapeutic treatment of CNS chronic inflammation associated with a disease or state in a mammal, including a human. The administration of KCOs, including the groups of benzopirans, cyanoguanidines, thioformamides, benzothiadiazines, pyridyl nitrates, pyrimidine sulfates, cyclobutenediones, DHP-related compounds, tertiary carbinols, 6-sulfonil-chromenes, 1,2,3-triazoles, pyridothiadiazines, benzothiazines, halogenquinazolins and phenylbenzimidazoles, and in particular, the compound diazoxide, result in a reduction of reactive microglial response in various CNS pathologies such as axonal injury, brain tumors, traumatic damage, neurodegeneration, spinal cord injury, infectious and autoimmune diseases. KCOs, isotopically modified, are also useful for the preparation of diagnostic agents for detection and follow-up of CNS chronic inflammation.
Owner:NEUROTEC PHARMA
Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents
This disclosure provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with new aminium salts of 1,2,3-triazoles which can be used as prodrugs to improve the solubility or pharmaceutical properties of 1,2,3-triazole containing compounds. More particularly, the present disclosure relates to compounds containing N-aminium-1,2,3-triazoles that are useful as antiviral agents and specifically for the treatment of HIV and AIDS.
Owner:VIIV HEALTHCARE UK (NO 5) LTD
Azoxystrobin-containing pesticide composition
InactiveCN103598188AEnsure safe productionGood Compounding StabilityBiocideFungicidesTriazole antifungalsAzoxystrobin
The invention discloses an azoxystrobin-containing pesticide composition. The pesticide composition comprises azoxystrobin and a triazole fungicide. The weight ratio of the azoxystrobin to the triazole fungicide is 1:60-60:1, and particularly the weight ratio of the azoxystrobin to the triazole fungicide is 1:1-3:2. The triazole fungicide is one of epoxiconazole, flutriafol, propiconazole, tebuconazole, hexaconazole, fluazinam or penconazole. The composition of the triazole fungicide and the azoxystrobin has significant synergistic effects, and can be used for disease control of fruit trees, cotton, rice, vegetables, and other crops, especially for disease control of rice blast, powdery mildew, gray mold and anthracnose.
Owner:陕西康禾立丰生物科技药业有限公司
Bicyclic, substituted triazoles as modulators of PPAR and methods of their preparation
The present invention is directed to certain novel triazole compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof. The present invention is also directed to methods of making and using such compounds and pharmaceutical compositions containing such compounds to treat or control a number of diseases mediated by PPAR such as glucose metabolism, lipid metabolism and insulin secretion, specifically Type 2 diabetes, hyperinsulemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for cardiovascular disease, Syndrome X, hypertriglyceridemia, hyperglycemia, obesity, and eating disorders.
Owner:METABOLEX INC
Sterilization compound containing triazole fungicide and azoxystrobin
ActiveCN101946775AStrong systemic bactericidal effectImprove the bactericidal effectBiocideFungicidesTriazole antifungalsEcological environment
The invention relates to a suspending agent type and water dispersible granule type sterilization compound which comprises the following raw materials in percentage by weight: 5-50% of triazole fungicide, 5-50 % of azoxystrobin and 3-15 % of accessory ingredient, wherein the triazole fungicide is one or the combination selected from Epoxiconazole, lutriafol, Cyproconazole and Penconazole, and theaccessory ingredient is composed of polycarboxylate dispersing agent and lignosulfonate wetting agent at the weight ratio of 0.15-6:1. The sterilization compound of the invention keeps good compound stability for two active ingredients in use; compared with the condition that single solvent is used for preventing and curing crop diseases, the sterilization compound enlarges disease prevention andcure range, delays the generation of resistance to drugs, obviously improves pesticide effect, reduces dosage and application times for each acre, preferably ensures the safe production of agriculture and protects ecological environment.
Owner:JIANGSU SEVENCONTINENT GREEN CHEM CO LTD
Pesticide composite containing picoxystrobin and triazole compound
InactiveCN102210308AImprove protectionGood treatment effectBiocideFungicidesTriazole antifungalsFlusilazole
The invention provides a pesticide composite containing picoxystrobin and triazole compound, comprising an effective active ingredient A and an effective active ingredient B, wherein the effective active ingredient A is the picoxystrobin; the effective active ingredient B is selected from one of epoxiconazole, flusilazole, tetraconazole, triazole and propiconazole. The pesticide composite disclosed by the invention comprises the following ingredients in percentage by weight: 1-60wt% of effective active ingredient A- picoxystrobin, 1-50wt% of effective active ingredient B selected from one of epoxiconazole, flusilazole, tetraconazole, triazole and propiconazole and the balance of accessory ingredient and butyl stearate. The pesticide composite disclosed by the invention is used for preventing and curing various diseases, such as crop powdery mildew, Septoria nodorum, leaf blight, downy mildew, smut, leaf spot, banana freckle, epidemic diseases, rust diseases, leaf mold, rice blast, banded sclerotial blight and anthracnose of grape and has obvious synergy.
Owner:陕西汤普森生物科技有限公司
Novel proton exchange membranes using cycloaddition reaction between azide and alkyne containing components
ActiveUS20060154129A1Improve stabilityReduce fuel cross-over rateIon-exchanger regenerationFinal product manufactureCross-linkTriazole antifungals
A process for making an ion-conducting polymer comprises cross-linking polymers having functional groups such as alkyne groups and azide groups. An example ion-conducting polymer has cross-links including nitrogen-containing heterocycles formed by the reaction between the functional groups, such as 1,2,3-triazole groups formed by a cycloaddition reaction between alkyne and azide groups. The ion-conducting polymer may be used in an ion-electrolyte membrane. Examples include a proton-electrolyte membrane useful for fuel cells.
Owner:TOYOTA MOTOR CO LTD
Sterilizing compound of ethirimol and triazole
ActiveCN101548677AGood control effectReduce pollutionBiocideFungicidesTriazole antifungalsFruit tree
The invention relates to a sterilizing compound of ethirimol and triazole, and the compound contains the ethirimol of synergic and effective amount, the triazole bactericide which is tebuconazole, difenoconazole, hexaconazole or myclobutanil, and diluent or carrier that is acceptable in pesticide, wherein the weight ratio of the ethirimol to the triazole bactericide which is tebuconazole, difenoconazole, hexaconazole or myclobutanil is 25:1 to 1:50. When being compounded with the triazole bactericide, the ethirimol has obvious synergy, and the amount of effective ingredients of the compound preparation is less than that when being used independently. The compound can be used for curing powdery mildew of fruit trees, melons, beans, solanaceous fruits, flowers, and the like.
Owner:SHAANXI BIAOZHENG CROP SCIENCE CO LTD
Stable matrix emulsion concentrates and stable aqueous and/or organic solvent compositions containing biocides
A stable matrix emulsion concentrate of a biocide, e.g. 3-iodopropynyl-2-butyl carbamate (IPBC) and / or a triazole fungicide, and stable aqueous and / or organic solvent formulations thereof, i.e. dilutable in water and / or an organic solvent are provided, which are particularly useful for treating wood products to provide protection against microorganisms and insects.
Owner:ISP INVESTMENTS LLC
Method of cosmetic depigmentation care by applying at least one aurone
at least one aurone or a natural or synthetic derivative of aurone, or an analogue of aurone, in which the independent phenyl ring can be substituted by a heterocycle of pyrrole, imidazole, triazole, pyridine, furan, or thiophene type, is disclosed as a cosmetic agent, or as an active substance, for the manufacture either of a cosmetic composition, or of a pharmaceutical composition, notably a dermatological composition, having a melanogenesis-inhibiting activity or a depigmenting activity, or an anti-tyrosinase activity.
Owner:COLETICA +1
Substituted triazolone benzyl amine triazole antifungal compounds and method for preparing same
InactiveCN1699351AStrong antifungal effectLow toxicityOrganic active ingredientsAntimycoticsAntifungalTriazole antifungals
The invention relates to a substituted triazolone benzyl amine triazole antifungal compound, i.e. 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[N-methyl-N-(2-substituted-2H-1,2,4-triazol-3-one-4-yl) benzylaminoformyl]-2-propanols compounds, their salts and their preparation process. The compounds has very strong antimycotic effect.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Trisubstituted 1,2,4 triazoles
The present invention relates to substituted 1-(alkyl)-3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.
Owner:JANSSEN PHARMA NV
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