Preparation method of neonicotinoid pesticide fluorescent molecularly imprinted polymer microspheres

Abstract

The invention discloses an anabasine pesticide fluorescence molecular imprinting polymeric microsphere preparation method and a performance evaluation method thereof. The preparation method comprises the following steps: taking template molecule clothianidin and imidacloprid, mixing the materials with 3-aminopropyltriethoxysilane, performing pre-assembly to obtain a first reaction solution; adding fluorescence SiO2 nano microsphere, tetraethoxysilane and ammoniacal liquor in the first reaction solution for a reaction to obtain a second reaction solution; and performing steps of centrifugation, washing and separation on the second reaction solution to obtain the product. The double-template molecular imprinting method is used for preparing a imprinting material capable of specifically identifying and absorbing a plurality of anabasine pesticides, extraction frequency and cost can be reduced, operation method is simple, the requirement of detection technology for multiple residue of the anabasine pesticides can be completely satisfied, and the problem that the single pesticide component is taken as the template molecule, so that several molecular imprinting polymers are subjected to batch synthesis for enriching anabasine pesticide target objects can be avoided.

Description

technical field [0001] The invention relates to the preparation technology of environmental functional materials, in particular to a preparation method of neonicotinoid pesticide fluorescent molecularly imprinted polymer microspheres. Background technique [0002] Nanospheres are small balls with a particle size of micron, which are widely used as liquid crystal spacers, drug carriers, enzyme carriers, etc. [0003] Nano-microsphere preparations can not only achieve long-acting goals by regulating and controlling the release rate of drugs, but also protect drugs from degradation by enzymes in the body, mask the bad taste of drugs, reduce the number of administration and drug stimulation, and reduce toxicity And adverse reactions, improve curative effect. In addition, microspheres also have a special affinity with certain cell tissues, and can be endocytosed by the reticuloendothelial system of organ tissues or fused by cells, concentrate in the target area and gradually dif...

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Problems solved by technology

[0008] In view of this, the preparation method and performance evaluation method of neonicotinoid pesticide fluorescent molecularly imprinted polymer microspheres provided by the present invention are aimed at solving the problem that most of the current preparations of neonicotinoid pesticide molecularly imprinted polymers only use a single pesticide component as a template Molecules, several molecularly imprinted polymers need to be synthesized in batches to enrich a variety of neonicotinoid pesticide targets, which increases the number of extraction times and costs of the targets, and the operation method is complicated and expensive.

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