Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

53results about How to "Fewer fetches" patented technology

System, circuit, and method for adjusting the prefetch instruction rate of a prefetch unit

A system, circuit, and method are presented for adjusting a prefetch rate of a prefetch unit from a first rate to a second rate by determining a probability factor associated with a branch instruction. The circuit and method may determine the probability factor based on a type of disparity associated with the branch instruction. The circuit and method may further be adapted to calculate the second rate based on the probability factor. The ability to adjust the prefetch rate of a prefetch unit advantageously decreases the number of memory transactions, thereby decreasing the power consumption of a processing unit.
Owner:VERISILICON HLDGCO LTD

Tea microwave and ultrasonic wave combined dynamic countercurrent extraction method and equipment

The invention discloses tea microwave and ultrasonic wave combined dynamic countercurrent extraction method and equipment. Microwave-ultrasonic wave combination stage-by-stage time-division extraction is adopted to give full play to the characteristics and the advantages of a microwave and ultrasonic wave extraction technology. In the whole extraction process, the flow direction of an extraction solvent is opposite to that of tea, thereby realizing a dynamic countercurrent continuous extraction function, being beneficial to extracting active ingredients of the tea and maximizing the tea extraction function and the efficiency; the rear end of extraction equipment is provided with a solid-liquid separation device, so that tea dregs after extraction can be dehydrated for realizing the comprehensive utilization of the tea dregs on one hand, and on the other hand, the filtered tea liquid can be circulated and utilized, thereby reducing the loss of the active ingredients in the tea liquid;the whole extraction process is completed at lower temperature, thereby being beneficial to preventing the active ingredients in the tea from being damaged by high temperature up to the hilt, saving the usage amount of the extraction solvent, reducing pollution and lowering the cost. The invention can realize industrial large-scale extraction production.
Owner:DAMIN FOODSTUFF ZHANGZHOU CO LTD

Tumor tissue tumor infiltrating lymphocyte (TIL) cell preparation method and dedicated culture medium

The invention relates to a tumor tissue tumor infiltrating lymphocyte (TIL) cell preparation method and a dedicated culture medium. The method comprises the following steps of tumor surrounding tissue obtaining, cell digestion, cell primary culture, cell subculture and cell collection, wherein a primary culture medium is based on a RPMI 1640 culture medium and prepared from the following concentration ingredients of 10% volume of human-derived serum, 20 to 45ng / ml of basic fibroblast growth factor (bFGF), 1 to 5mg / ml of riboflavin, 70 to 90ng / ml of cortisol, 10 to 25mg / ml of sodium dihydrogen phosphate monohydrate, 47 to 62ng / ml of recombinant human leukaemia inhibitory factor (LIF) and 500 to 800U / ml of IL-2; a subculture medium is based on the RPMI 1640 culture medium and prepared from the following concentration ingredients of 10% volume of the human-derived serum, 20 to 40mmol / L of HEPES, 1000 to 2000U / ml of the IL-2, 0.03 to 0.07mmol / L of beta-mercaptoethanol and 5 to 15ng / ml of sodium phosphate. According to the preparation method, an existing culture medium is improved, different culture mediums are utilized to culture the TIL cells in pertinence, TIL cell expansion capacity is improved, meanwhile a culture period is reduced, a culture complexity degree is reduced, a use amount of the IL-2 is reduced, and toxic reaction is reduced.
Owner:CENTURY BIOSTRENGTH BEIJING PTY LTD

Extraction method of deep-sea fish gelatin

The invention discloses an extraction method of deep-sea fish skin gelatin, and the method comprises the following steps of putting cleaned fish skin in conditioning fluid which is prepared from compound organic acid and stirring, cleaning the conditioned fish skin by water at room temperature, putting the cleaned fish skin in weakly acidic water solution at 30-60 DEG C for extraction, combining the extracting solution, filtering the extracting solution by 100-mesh filter cloth, and carrying out concentration and drying to obtain the gelatin. The method provided by the invention is gentler, and the prepared product is high in yield and purity, large in molecular weight, narrow in molecular weight distribution, shallow in color and light in fishy smell.
Owner:QINGDAO HUAKE BIOLOGICAL TECH CO LTD

Celery seed extract, preparation and preparation method thereof

The present invention relates to a celery seed extract, a preparation and a preparation method thereof. The preparation method comprises: taking dried celery seeds, and carrying out reflux extraction 1-2 times with 2-4 times the volume of an ethanol aqueous solution with a volume fraction of 95%; collecting the extraction liquids, and carrying out pressure reducing concentration to obtain a thick extract; suspending the thick extract in water having the volume 0.5-1 time the volume of the raw material, extracting 2-4 times with an extraction reagent, and combining the organic phases after completing the extracting to obtain a crude extract; weighing silica gel having the mass of 35-55 times the mass of the crude extract, activating for 1 h at a temperature of 130 DEG C, and loading into a chromatography column; taking the crude extract, and injecting in a concentration of 0.2-0.5 g / ml; and carrying out gradient elution with petroleum ether-dichloromethane-ethyl acetate, collecting the flow, and carrying out pressure reducing concentration to obtain the celery seed extract. According to the present invention, the preparation method has characteristics of simple preparation process, less extraction number, and high yield; and the obtained celery seed extract has the good serum uric acid lowering effect.
Owner:赛隆药业集团股份有限公司

Method for extracting and purifying Gypenoside from Gynostemma pentaphyllum

The invention relates to a method for extracting and purifying Gypenoside from Gynostemma pentaphyllum. The method is as below: crushing and sieving Gynostemma pentaphyllum, extracting by ethanol, and filtering and concentrating an extracted liquid to an alcohol-free state; passing the concentrated liquid through macroporous resin for adsorption, eluting by water to a clarified state, eluting by alcohol solution, and concentrating the eluent to an alcohol-free state; extracting the concentrated liquid with an organic solvent, concentrating and drying, and at the same time recovering the organic solvent. The invention has the advantages of simple process, reasonable technology and economical affordability; the adsorption-extraction combined technology is employed to obtain a product with high purity. The method adapts to the production of small and medium-sized enterprises, and reduces the equipment required by production and the cost of production.
Owner:宁波中药制药股份有限公司

Maggot oil extraction by ultrasonic-assisted extraction method and maggot oil

The invention discloses maggot oil extraction by ultrasonic-assisted extraction method and maggot oil, and the maggot oil extraction comprises the following steps: a drying step, to be more specific, performing 24-48 hours of freezing drying under the condition of the vacuum degree of 0.06-0.08MPa and the temperature of-40 to-50 DEG C; an extraction step, to be more specific, crushing the dried maggot, sieving, taking 30-80 mesh maggot powder, adding a solvent with the weight of 5-10 times of that of the maggot powder, extracting for 15-40min under the condition of the ultrasonic power of 250-400W and the temperature of 20 to 30 DEG C, then soaking for 12 to 24 hours, and filtering to obtain a filtrate and filter residues; a centrifugal separation step, to be more specific, performing 10-20min of centrifugal separation of the filtrate under the condition of 3000-4500r / min to obtain supernatant, removing a solvent of the obtained supernatant by reduction vaporization; and a collecting step, to be more specific, performing vacuum drying on the maggot oil with the solvent removed to obtain the final product maggot oil. The maggot oil extraction is short in reaction period, reduces the times of extraction, and is simple in process and high in product yield, and the effective components of the obtained maggot oil are not destroyed.
Owner:中海海洋无锡海洋工程装备有限公司

Method for extracting ganglioside from animal tissue

The present invention discloses a method for extracting ganglioside from animal tissue. Said method adopts one kind of several kinds of polar solvents matched with polarity of ganglioside to greatly raise extraction efficiency of ganglioside, and adopts inversed phase extraction method to remove impurity from the extract to raise product grade and reduce production cost. The purity of the ganglioside prepared by using said invented method can be up to 81%, and its cholesterol and neutral lipide contents are low. Said invention is simple in production process, suitable for scale production, its product purity is high, and can meet the food and medicinal requirements.
Owner:上海宝智生物制品有限公司

Method for preparing gypenoside in gypenoside grains

The invention discloses a method for preparing gypenoside in gypenoside grains. The method comprises the following steps of: (1) crushing gynostemma herb into coarse powder, adding the coarse powder to a multifunctional extract pot, adding 6-8 times of water, adding an emulsifying agent to mix uniformly, extracting twice through backflow, the time consumed for each extraction is 1h, and collecting an extracting solution; and (2) regulating a pH value of the collected extracting solution to be 7-8, filtering, precipitating, taking out filter liquid, carrying out adsorption and chromatography through macroporous resin, eluting once or twice by utilizing ethanol with the concentration of 50-70% to collect eluent, recovering the ethanol, reducing pressure and concentrating, spraying and drying to obtain a powder extract. The gynostemma herb is extracted by the method disclosed by the invention, the yield of the gypenoside is increased, and the yield of the extract is increased by more than 30%; in addition, the extracting time and times of preparation of the gypenoside can be reduced, the production period of the gynostemma herb extract can greatly shortened, and the production cost is reduced.
Owner:湖南华宝通制药有限公司

A Lugua polypeptide injection

The invention belongs to the technical field of medicines and discloses a Lugua polypeptide injection. According to a preparing method of the injection, a preparing method of a deer bone extract liquid includes adding composite enzymes into deer bone, extracting the deer bone with high-temperature water, adjusting the pH value with an acid, heating, allowing the mixture to stand at 20-30 DEG C, concentrating, allowing the concentrate to stand at 20-30 DEG C, adjusting the pH value with an alkali, concentrating, allowing the concentrate to stand at 20-30 DEG C, adjusting the pH value with an acid, performing gradient ultrafiltration, and storing at a low temperature to obtain the deer bone extract liquid; a preparing method of a muskmelon seed extract liquid includes extracting muskmelon seeds with high-temperature water, adjusting the pH value with an acid, allowing the mixture to stand at 20-30 DEG C, concentrating, centrifuging, performing ultrafiltration, adjusting the pH value with an alkali, freezing and storing with gradient temperatures, unfreezing, concentrating, centrifuging, adjusting the pH value with an acid, performing gradient ultrafiltration, and storing at a low temperature to obtain the muskmelon seed extract liquid; and the deer bone extract liquid and the muskmelon seed extract liquid are mixed, subjected to ultrafiltration and prepared into the injection.
Owner:TIBET YUHENG YANGGUANG MEDICINE TECH CO LTD

Method for preparing panax notoginseng saponins

The invention discloses a method for preparing panax notoginseng saponins from panax notoginseng saponins particles. The method comprises the following steps: (1) smashing the pseudo-ginseng medical material into coarse powder, putting the powder into a multi-functional extraction tank, adding 6-8 times of water, adding an emulgator, mixing uniformly, and then reflux extracting twice for one hour each time, and collecting the extracting solution; (2) adjusting the pH value of the collected extracting solution to be 7-8, after filtration and precipitation, taking the filtrate, performing adsorption and chromatography through macroreticular resin, eluting once or twice using ethanol with the concentration of 50-70%, collecting the eluant, after recovering ethanol, condensing under reduced pressure, and performing spray drying to obtain powder extract. By adopting the method provided by the invention to extract pseudo-ginseng, the yield of panax notoginseng saponins is increased, the extract yield is increased by 30% or above, the extraction time and the number of extraction times for preparing panax notoginseng saponins are reduced, the production period for extracting pseudo-ginseng is greatly shortened, and the production cost is reduced.
Owner:GUANGXI UNIV

Data processing method, device and apparatus and computer readable storage medium

The invention discloses a data processing method and device and a computer readable storage medium. The method comprises the following steps of setting a plurality of specific intervals for the specific function, and presetting a group of fitting parameters for each specific interval; preprocessing the input data falling out of the specific interval to obtain compensation information and effectivedata falling into the specific interval, determining corresponding fitting parameters according to the specific interval into which the effective data falls, and performing fitting operation according to the sum of the effective data to obtain an approximate fitting result; performing post-processing operation according to the approximate fitting result and the compensation information to obtaina final result corresponding to the input data. According to the invention, the occupation of a storage space in a function fitting operation process can be reduced, the fitting operation efficiency is improved, and the fitting operation time is reduced.
Owner:中昊芯英(杭州)科技有限公司

Injection preparation prepared from beer bones and muskmelon seeds

The invention belongs to the technical field of medicine and discloses an injection preparation made of deer bone and melon seeds as raw materials; the preparation method of the injection preparation is as follows: deer bone is extracted to obtain a deer bone extract, and melon seeds are extracted to obtain a melon seed extract; wherein The preparation method of deer bone extract is as follows: take deer bone, add compound enzyme, extract with high-temperature water, adjust pH value with acid, heat, stand at 20-30°C, concentrate at 20-30°C, adjust pH value with alkali, concentrate at 20°C Stand at -30°C, adjust the pH value with acid, gradient ultrafiltration, and store at low temperature to obtain the deer bone extract; the preparation method of the sweet melon seed extract is: take the melon seeds and extract with high temperature water, adjust the pH value with acid, and statically at 20-30°C After concentration, centrifugation, ultrafiltration, alkali adjustment of pH value, gradient temperature cryopreservation, concentration after thawing, centrifugation, acid adjustment of pH value after centrifugation, gradient ultrafiltration, low temperature storage, to obtain the melon seed extract; the deer bone extract and The extracts of melon seeds are mixed, ultrafiltered, and prepared into injection preparations.
Owner:TIBET YUHENG YANGGUANG MEDICINE TECH CO LTD

Method for ultra high-pressure extraction of escin from Chinese buckeye seeds based on freeze drying

The invention discloses a method for ultra high-pressure extraction of escin from Chinese buckeye seeds based on freeze drying. The method includes: firstly crushing and soaking Chinese buckeye seed herbal material, then performing freeze drying, and then conducting ultra high-pressure extraction, wherein the extraction step includes a pressure boosting stage, a pressure maintaining stage, a pressure relief stage and the like. According to the invention, Chinese buckeye seeds are subjected to freeze drying treatment to change the internal structure of the herbal material texture, so that cellwalls can rupture more easily, and active ingredients can exude more easily, thereby reducing the pressure and number of times of ultra high-pressure extraction, and lowering energy consumption and cost.
Owner:WUHAN AIMIN PHARMA

Method for effectively extracting active ingredients of traditional Chinese medicine by using freezing and dissolving method

The invention discloses a method for effectively extracting active ingredients of a traditional Chinese medicine and belongs to an extraction method. The method comprises the following steps: crushing raw materials of the traditional Chinese medicine into powder with 10 to 200 meshes to obtain powder A; putting the powder A in the environment of 40 DEG C below zero to 0 DEG C and carrying out first-time freezing until the internal temperature of the powder A is consistent with the external temperature of the powder A, then putting the powder A in the environment of 40 DEG C below zero to 0 DEG C for 0.1 to 60 minutes, and gradually raising the temperature of the powder A to normal temperature, and enabling the powder A to naturally absorb water in the process; staying at normal temperature for 0.5 to 24 hours to obtain powder B. Water infiltrating into cells is condensed into ice crystals when the water freezes again by carrying out two-time freezing and dissolving on crushed powder and ingeniously utilizing the characteristic that low-temperature powder naturally absorbs the water; the cell wall of an active drug can be effectively destroyed by the ice crystals, so that the extraction rate of active ingredients of plants is greatly improved, and the extraction time and extraction times can be effectively reduced; the method is particularly suitable for extracting the active ingredients of high-value traditional Chinese medicine or other precious plants.
Owner:YUNNAN HEMPSON BIO-TECH CO LTD

Method for extracting galanthamine from lycoris plant

The invention discloses a method for extracting galanthamine from a lycoris plant. The method comprises the following steps: (1) extraction: weighing the treated lycoris powder, adding the lycoris powder into water with pH of 4.5 at a feed-liquid ratio of 1:10 and a unit proportion of g / mL; adding the mixed enzyme of cellulase accounting for 1.0-3.0% of the mass of the lycoris powder and pectinase, wherein the mass ratio of the cellulase to pectinase is 1:1; performing enzymolysis for 20-100min at 50 DEG C; performing ultrasonic treatment for 5-25min and centrifuging for 20min at 5,000r / min; and fetching the supernate to obtain galanthamine extract; and (2) purification: solvent extraction; adsorption by cation exchange resin; C18 reverse phase silica gel column chromatography; normal-phase silica gel column chromatography; recrystallization: dissolving the dried product III obtained in the previous step with ethanol, crystallizing to obtain a crude product of galanthamine, filtering and performing vacuum drying at 50-60 DEG C to obtain galanthamine. The method disclosed by the invention has the advantages of easiness in operation, short extraction time, high extraction rate, small dosage of solvent and relatively low cost; and the purifying process is environment-friendly and the purity is high and can reach 99.2%.
Owner:JISHOU UNIVERSITY

New technology for extracting Chinese magnoliavine fruit lignanoid with high efficiency

The invention belongs to the technical field of medicines, and relates to the new technology for extracting Chinese magnoliavine fruit lignanoid with high efficiency. A preparation process comprises the following steps of: crushing Chinese magnoliavine fruit, adding 60 to 100 percent of methanol or ethanol and 0.5 to 5 percent of surfactant, performing reflux extracting for 1 to 2 times, and mixing extract, wherein the reflux extracting is performed for 1 to 2 hours every time; concentrating the extract under reduced pressure, removing the methanol or the ethanol, adding ester organic solvent for extracting; and concentrating an extract phase to recover the ester organic solvent, dissolving in proper amount of water, and purifying by adopting adsorbent resin, and eluting by 30 to 90 percent of ethanol to obtain the Chinese magnoliavine fruit lignanoid with 70 to 98 percent of lignanoid. The new technology has the characteristics that: after the surfactant is added, the extraction efficiency can be improved by over 30 percent, the extracting time can be reduced, clarified solution can be obtained, and an upper absorption column is not blocked due to ester insoluble substances; and by adding the ester organic solvent, pigment impurities can be removed effectively, the competitive adsorption of pigment on the absorption column can be reduced, and the purity of final products can be improved.
Owner:YANTAI UNIV

Extraction method of deep-sea fish gelatin

The invention discloses an extraction method of deep-sea fish skin gelatin, and the method comprises the following steps of putting cleaned fish skin in conditioning fluid which is prepared from compound organic acid and stirring, cleaning the conditioned fish skin by water at room temperature, putting the cleaned fish skin in weakly acidic water solution at 30-60 DEG C for extraction, combining the extracting solution, filtering the extracting solution by 100-mesh filter cloth, and carrying out concentration and drying to obtain the gelatin. The method provided by the invention is gentler, and the prepared product is high in yield and purity, large in molecular weight, narrow in molecular weight distribution, shallow in color and light in fishy smell.
Owner:QINGDAO HUAKE BIOLOGICAL TECH CO LTD

Video image decoding method and terminal based on hevc protocol

InactiveCN108235028AReduce occupancyReduce the number of reads of all-zero blocksDigital video signal modificationDecoding methodsCut off value
The invention provides a video image decoding method based on a hevc protocol. The video image decoding method based on the hevc protocol comprises the steps of: traversing a 32*32 source pixel blockin a current frame image, obtaining a non-zero block and an all-zero block in the 32*32 source pixel block, and determining the relative positions of the non-zero block and the all-zero block in the 32*32 source pixel block; determining the cut-off value of the non-zero block according to the relative positions; and, operating the non-zero block based on a pre-set decoding rule and the cut-off value, so that a decoded image is obtained. According to the video image decoding method and terminal based on hevc protocol provided by the invention, the non-zero block and the all-zero block are separately processed; the occupied memory in the decoding process can be reduced; simultaneously, the memory reading and integer multiplication operation can be reduced; and the decoding efficiency is increased.
Owner:GUANGZHOU HUADUO NETWORK TECH

Method for extracting high-purity adenostemmoic acid B from zanthoxylum acanthopodium

The invention relates to a method for extracting high-purity adenostemmoic acid B from zanthoxylum acanthopodium. The method comprises the following three steps of: 1) ethanol extraction: crushing zanthoxylum acanthopodium rhizomes, adding 0.5 to 5 percent surfactant, performing reflux extraction by adopting ethanol, and concentrating the extract till ethanol smell does not exist; 2) macroporous resin adsorption: separating the obtained concentrate through macroporous adsorption resin, performing gradient elution by using water or ethanol, reclaiming ethanol from the eluent under reduced pressure, and obtaining an extract; and 3) high-speed countercurrent chromatography purification: further purifying the obtained extract by using high-speed countercurrent chromatography, and thus obtaining the adenostemmoic acid B with the purity of over 95 percent. Compared with the conventional extraction process, the method has the advantages that: after the surfactant is added, the extraction rate can be improved, the extraction frequency is reduced, a clear solution can be obtained, and an adsorption column is not blocked during filling; and the method has the advantages of simplicity, convenience, fastness, high preparation quantity, high product purity and the like, and is easy in popularization and use.
Owner:NANJING ZELANG MEDICAL TECH

Novel preparation method of coriolus versicolor polysaccharopeptide

The invention discloses a novel preparation method of coriolus versicolor polysaccharopeptide, which comprises the following steps of: directly heating and boiling coriolus versicolor fermentation broth in a fermentation tank, and directly extracting hyphae in the fermentation broth by using filtrate in the fermentation broth, so that the problem of loss of effective components in the hyphae possibly generated after the hyphae are separated and dried in the original process is avoided, a mixture of intracellular polysaccharide and extracellular polysaccharide of the coriolus versicolor can be obtained at the same time, and the yield and the utilization rate are improved. In addition, the method is simple in technological process and easy to operate.
Owner:JIANGSU SHENHUA PHARMA

Process for preparing broad spectrum antimicrobial triclosan

The invention provides a process for preparing broad spectrum antimicrobial triclosan, which consists of using 2,5-dichloronitrobenzene and 2,4-dichlorophenol as raw material, carrying out in sequence etherification reaction, nitro group deacidizing, diazotization hydrolytic reaction, purifying with toluene for three times. The invention can decrease extraction frequency and reduce production costs substantially.
Owner:季文彬

Tea microwave and ultrasonic wave combined dynamic countercurrent extraction method and equipment

The invention discloses tea microwave and ultrasonic wave combined dynamic countercurrent extraction method and equipment. Microwave-ultrasonic wave combination stage-by-stage time-division extraction is adopted to give full play to the characteristics and the advantages of a microwave and ultrasonic wave extraction technology. In the whole extraction process, the flow direction of an extraction solvent is opposite to that of tea, thereby realizing a dynamic countercurrent continuous extraction function, being beneficial to extracting active ingredients of the tea and maximizing the tea extraction function and the efficiency; the rear end of extraction equipment is provided with a solid-liquid separation device, so that tea dregs after extraction can be dehydrated for realizing the comprehensive utilization of the tea dregs on one hand, and on the other hand, the filtered tea liquid can be circulated and utilized, thereby reducing the loss of the active ingredients in the tea liquid;the whole extraction process is completed at lower temperature, thereby being beneficial to preventing the active ingredients in the tea from being damaged by high temperature up to the hilt, saving the usage amount of the extraction solvent, reducing pollution and lowering the cost. The invention can realize industrial large-scale extraction production.
Owner:DAMIN FOODSTUFF ZHANGZHOU CO LTD

Extraction process of active component in northern schisandra

The present invention relates to Chinese medicine material extracting process, and is especially the extraction process of active component in northern schisandra. The extraction process includes the steps of selection of northern schisandra, crushing, heating, microwave treatment, reflux extraction, filtering, high speed centrifugal separation and vacuum drying. The present invention has the features of high extraction rate, high production efficiency and high product quality.
Owner:STATE GRID CORP OF CHINA +1

Method and device for scheduling update sections of electronic book

The invention provides a method and a device for scheduling update sections of an electronic book. The method comprises the steps of aiming at a uniform resource locator (URL) newly added in a related site of the electronic book, determining the Pattern of the URL according to a URL Pattern dictionary of the site to which the URL belongs; reversely recognizing the electronic book corresponding to the URL from a preset electronic book pattern information library according to the Pattern of the URL; determining that the recognized electronic book is the updated electronic book; and initiating scheduling to the section list page of the updated electronic book in the site to which the URL belongs, to capture all update sections of the updated electronic book. With the application of the method, the updated electronic book can be quickly recognized, and the capture speed of the update sections is improved; furthermore, the frequent capture operation is not needed, and the capture efficiency of the update sections is improved.
Owner:BEIJING QIHOO TECH CO LTD

Qinbaohong solution preparation used for inhalation and preparation method thereof

The invention belongs to the field of a preparation, and particularly relates to a Qinbaohong solution preparation used for inhalation and a preparation method thereof. The Qinbaohong solution preparation comprises an active ingredient, an auxiliary agent and a solvent; the Qinbaohong solution preparation is prepared by the active ingredients extracted from effective components of Chinese traditional medicine Rhododendron dahuricum, manchurian lilac bark and radix scutellariae. The Qinbaohong solution preparation is safe, effective and high in bioavailability, and has the advantages of low usage dosage, quick onset, good curative effect and no other side effects.
Owner:BEIJING INCREASE INNOVATIVE DRUG RESEARCH CO LTD

New technology for extracting Chinese magnoliavine fruit lignanoid

The invention belongs to the technical field of medicines, and relates to the new technology for extracting Chinese magnoliavine fruit lignanoid. A preparation process comprises the following steps of: crushing Chinese magnoliavine fruit, adding 60 to 100 percent of methanol or ethanol and 0.5 to 5 percent of surfactant, performing reflux extracting for 1 to 2 times, and mixing extract, wherein the reflux extracting is performed for 1 to 2 hours every time; concentrating the extract under reduced pressure, removing the methanol or the ethanol, adding ester organic solvent for extracting; and concentrating an extract phase to recover the ester organic solvent, dissolving in proper amount of water, and purifying by adopting adsorbent resin, and eluting by 30 to 90 percent of ethanol to obtain the Chinese magnoliavine fruit lignanoid with 70 to 98 percent of lignanoid. The new technology has the characteristics that: after the surfactant is added, the extraction efficiency can be improved by over 30 percent, the extracting time can be reduced, clarified solution can be obtained, and an upper absorption column is not blocked due to ester insoluble substances; and by adding the ester organic solvent, pigment impurities can be removed effectively, the competitive adsorption of pigment on the absorption column can be reduced, and the purity of final products can be improved.
Owner:YANTAI UNIV

A kind of celery seed extract and its preparation and preparation method

The invention relates to a celery seed extract and its preparation and preparation method. Take the dry seeds of celery, and extract 1-2 times with 2-4 times the volume of ethanol aqueous solution with a volume fraction of 95%; collect the extract, concentrate under reduced pressure to obtain a thick extract; suspend the thick extract in the raw material 0.5 ‑1 times the volume of water, extracted 2‑4 times with the extraction reagent, combined the organic phases after extraction to obtain the crude extract; weighed silica gel with 35‑55 times the mass of the crude extract, activated it at 130°C for 1 hour, and loaded it for chromatography Column; take the crude extract and load it at a concentration of 0.2-0.5g / ml; elute with a gradient of petroleum ether-dichloromethane-ethyl acetate, collect the fractions, and concentrate under reduced pressure to obtain the celery seed extract. The invention has the advantages of simple preparation process, less extraction times and high yield, and the obtained celery seed extract has better effect of reducing serum uric acid.
Owner:赛隆药业集团股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products