Sorghum root extract, and preparation method and application thereof
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A root extract and extract technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., to achieve the effect of high safety, simple preparation method and low price
Inactive Publication Date: 2017-07-14
THE KEY LAB OF CHEM FOR NATURAL PROD OF GUIZHOU PROVINCE & CHINESE ACADEMY OF SCI
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At present, there are no related literature reports on sorghum root extract and its preparation method and anticoagulant effect at home and abroad.
Method used
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Embodiment 1
[0014] A preparation method of sorghum root extract, comprising: cutting the dried sorghum root into small pieces, adding water for extraction, the extraction temperature is 70°C, the weight ratio of solid to liquid is 1:12, extraction is performed 3 times, each time for 1.5 h, and the water decoction is combined Concentrate to a liquid extract, add edible alcohol until the final concentration of alcohol is 60%, let it stand for 12-24 hours, filter, concentrate the filtrate, and obtain a dry extract that is the sorghum root extract.
Embodiment 2
[0016] A preparation method of sorghum root extract, comprising: cutting the dried sorghum root into small pieces, adding water to extract, the extraction temperature is 85°C, the weight ratio of material to liquid is 1:12, extracting twice, each time for 3 hours, and combining the water decoction Concentrate to a liquid extract, add edible alcohol until the final concentration of alcohol is 70%, let it stand for 12-24 hours, filter, concentrate the filtrate, and obtain a dry extract that is the sorghum root extract.
Embodiment 3
[0018] A preparation method of sorghum root extract, comprising: cutting the dried sorghum root into small pieces, adding water to extract, the extraction temperature is 100°C, the weight ratio of solid to liquid is 1:10, extracting twice, each time for 2 hours, and combining the water decoction Concentrate to a liquid extract, add edible alcohol until the final concentration of alcohol is 80%, let it stand for 12-24 hours, filter, concentrate the filtrate, and obtain a dry extract that is the sorghum root extract.
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Abstract
The invention discloses a sorghum root extract, and a preparation method and application thereof. The preparation method comprises the following steps of cutting sorghum roots into small sections with a straw cutter, adding water to extract the small sections for 1 to 3 times, wherein the extracting temperature is 70 to 100 DEG C, the weight ratio of materials to liquid is 1:8 to 1:12, and each time lasts for 1.5 to 3 hours, combining water decoctions, and concentrating the water decoctions to a fluid extract; and adding an edible alcohol until the final alcohol concentration is 60 to 80 percent, standing for 12 to 24 hours, filtering, concentrating a filtrate, and drying to obtain the sorghum root extract. The sorghum root extract is applied to the preparation of drugs for treating diseases caused by endovascular embolization or thrombus, and preventing stroke or other thrombotic diseases. The sorghum root extract is good in anticoagulation, high in safety, low in cost, simple in preparation method and low in production cost.
Description
technical field [0001] The present invention relates to the field of medical technology, in particular to a sorghum root extract, and also to a preparation method of the sorghum root extract, and the preparation of the sorghum root extract for treating intravascular embolism or thrombus, preventing stroke or other Use in medicaments for thrombotic diseases. Background technique [0002] Sorghum root is a plant of the genus Sorghum Sorghom vulgare Pers. The root is a traditional Chinese herbal medicine, which is recorded in "Compendium of Materia Medica", "Dictionary of Chinese Medicine", "Chinese Materia Medica" and other traditional Chinese medicine classics. Its nature and flavor are sweet, flat, and non-toxic; it has the effects of relieving asthma, diuresis, dredging collaterals, etc., and can be used to treat symptoms such as cough, dyspnea, dysuria, and foot and knee pain. It is also widely used in Guizhou folk. "Guizhou Herbal Medicine" also records that sorghum r...
Claims
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Application Information
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P7/02A61P9/10
CPCA61K36/899A61K2236/331A61K2236/39A61K2236/53
Inventor 杨娟颜幻彭梅杨小生李齐激
Owner THE KEY LAB OF CHEM FOR NATURAL PROD OF GUIZHOU PROVINCE & CHINESE ACADEMY OF SCI
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