Traditional Chinese medicine for treating damp-heat and blood-stasis type hepatocellular jaundice and preparation method thereof

A technology of damp-heat stasis and hepatocytes, applied in medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems affecting the quality of life of patients, unfavorable prognosis of jaundice patients, and aggravation of symptoms of spleen-stomach disharmony in patients. To achieve the effect of exact curative effect and no side effects

Inactive Publication Date: 2017-09-01
CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Most of our common syndrome differentiation types of jaundice emphasize dampness, heat, blood stasis, poison, phlegm and other evils, while it is easy to ignore the cause of jaundice, and it is easy to use many cold and cold medicines without caring about protecting the spleen and stomach, which may lead to symptoms of spleen and stomach disharmony in patients Aggravation, thus affecting the quality of life of patients, is not conducive to the prognosis of patients with jaundice

Method used

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  • Traditional Chinese medicine for treating damp-heat and blood-stasis type hepatocellular jaundice and preparation method thereof
  • Traditional Chinese medicine for treating damp-heat and blood-stasis type hepatocellular jaundice and preparation method thereof
  • Traditional Chinese medicine for treating damp-heat and blood-stasis type hepatocellular jaundice and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] To prepare the traditional Chinese medicine for treating damp-heat stagnation type hepatocellular jaundice of the present invention, each sample is made of the raw materials shown in Table 1 in parts by weight. .

[0025] Table 1 Prescriptions of traditional Chinese medicine for the treatment of hepatocellular jaundice of damp-heat stagnation type

[0026]

[0027] The traditional Chinese medicine of the present invention can be made into a mixture and can be decocted or taken, and can also be made into pills, capsules or tablets. Mixture drink 30ml each time, three times a day.

[0028]Or decoction with water: one dose a day, decocted twice. Take one portion of any sample in Table 1 (the grams of each component in each sample is shown in the formula in Table 1), soak it in 600ml of cold water for one hour, boil it for the first time, then change the heat to a simmer and fry for 30 minutes , take 150ml of juice; the second time add 400ml of cold water, after boili...

Embodiment 2

[0029] Example 2 Treatment of damp-heat and blood stasis type hepatocellular jaundice with traditional Chinese medicine of the present invention

[0030] 1. Objects and methods

[0031] Design: Randomized, parallel, controlled trial method. Choose Tuihuang Mixture (A) and Yinzhihuang Granules (B) as a control, that is, to observe the curative effect of A and B in treating damp-heat stagnation type hepatocellular jaundice, so as to compare the strength of A and B in improving clinical symptoms; with the help of modern inspection technology , through the comparison of TBIL, DBIL, DBIL / TBIL, ALT, and AST in the two groups of patients before and after the experiment, to observe the level of intervention.

[0032] Unit: Ward and Outpatient Department of Liver Diseases, Chongqing Hospital of Traditional Chinese Medicine.

[0033] Objects: Selected 60 patients with hepatocellular jaundice of damp-heat stagnation type from August 2011 to December 2014 in the Department of Liver Dise...

Embodiment 3

[0094] There were no adverse reactions in the treatment group and the control group during the medication period, and there were no significant changes in blood and urine routine tests in the two groups after treatment, and no serious liver and kidney damage and bleeding and other side effects occurred. No one fell off due to side effects. Example 3 The protective effect of traditional Chinese medicine of the present invention on ANIT-induced cholestatic liver injury

[0095] 1 material

[0096] 1.1 Experimental animals

[0097] Healthy and clean SD rats, half male and half male, weighing 180-220 grams, were provided by the Experimental Animal Center of Chongqing Medical University. Experimental animal license number: SCXK (Chongqing) 20070001.

[0098] 1.2 Drugs and reagents

[0099] Anti-yellowing mixture (specification 1g / ml, prepared by sample 6 in Example 1), 1-naphthyl isothiocyanate (ANIT) is from Shanghai Aladdin Company, alanine aminotransferase (ALT), asparagus a...

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Abstract

The invention discloses traditional Chinese medicine for treating damp-heat and blood-stasis type hepatocellular jaundice. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 20 to 40 parts of herba artemisiae scopariae, 3 to 9 parts of raw radix et rhizoma rhei, 8 to 16 parts of lignum sappan, 10 to 20 parts of herba dianthi, 10 to 20 parts of Japanese ardisia herb and 20 to 40 parts of herba hyperici Japonici. A preparation method of the traditional Chinese medicine comprises the following steps: smashing all raw materials in formula ratios into powder, and uniformly mixing the powder, thus preparing a traditional Chinese medicine preparation. In the traditional Chinese medicine disclosed by the invention, six traditional Chinese medicine materials have the functions of clearing heat, promoting diuresis, expelling damp evil from urine and stool and leading jaundice out of orifices, all medicine materials are combined for use, are in synergistic effect, complement each other and work together to obtain the effect of removing jaundice without the disadvantage of damaging the spleen and the stomach. The traditional Chinese medicine disclosed by the invention is definite in treatment effect, has no toxic and side effects and is safe and reliable.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating hepatocellular jaundice of damp-heat stagnation type and a preparation method thereof. Background technique [0002] Jaundice, also known as "jaundice", is a disease characterized by damp heat and epidemic toxins, blockage of liver and gallbladder qi, abnormal catharsis, bile overflow, and yellow body, eyes, and urine as the main symptoms. It has basically the same meaning as jaundice in modern medicine, including obstructive jaundice, hemolytic jaundice, hepatocellular jaundice in modern medicine, and any disease that causes abnormally high bilirubin in the blood. Generally speaking, most jaundice can gradually subside within a month if the differential diagnosis is correct and treated in time. Clinically, refractory jaundice (or intractable jaundice) is called refractory jaundice if jaundice occurs repeatedly or lasts for more than h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61P1/16
CPCA61K36/185A61K36/282A61K36/36A61K36/48A61K36/708A61K2300/00
Inventor 陈新瑜刘华宝文洪宇
Owner CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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