Stem cell composition and face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing

A composition and stem cell technology, applied in skin care preparations, animal cells, cosmetic preparations, etc., can solve problems such as limited repair effect, and achieve the effects of improving skin texture, improving skin, and accelerating wound healing.

Inactive Publication Date: 2017-12-01
GUANGZHOU ZISHENG BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the technical problem of limited repairing effect in the existing cosmetic technology, the present invention provides a new type of stem cell composition and facial rejuvenation beauty preparation for anti-wrinkle, whitening and moisturizing, which has good repairing effect and long maintenance time

Method used

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  • Stem cell composition and face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing
  • Stem cell composition and face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing
  • Stem cell composition and face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0025] Take 40mL of healthy fetal umbilical cord blood, add 4mL of sodium citrate anticoagulant, centrifuge at 300g for 10min, then use a Pasteur pipette to absorb the upper layer of plasma, transfer it to a 50mL centrifuge tube, and continue to centrifuge at 1500g for 10min. Aspirate and discard part of the plasma after centrifugation, leaving 1 mL of plasma at the bottom of the centrifuge tube. Finally, resuspend the plasma and bottom platelets to make PRP.

[0026] Take 300uL PRP, divide it into 3 parts, and use a blood cell analyzer to detect the number of platelets within 1 hour. Table 1 shows the test results, indicating that the content of platelets in PRP is above 400, which meets the preparation standards and can be used in facial rejuvenation preparations preparation.

[0027] Table 1

[0028] group

Embodiment 3

[0030] Prepare A, B and C three kinds of facial rejuvenation beauty preparations respectively according to the formula described in table 2, and its concrete preparation process is as follows:

[0031] 1. Preparation of nicotinamide mother liquor: Weigh nicotine base powder, add physiological saline, dissolve to obtain nicotinamide mother liquor with a concentration of 500 mg / mL, filter it with a 0.22 μm filter membrane, and place it in a refrigerator at 4°C until use.

[0032] 2. Preparation of EGF solution: Take out a bottle of EGF freeze-dried powder and a bottle of solvent respectively, absorb the solvent with a disposable syringe, pour it into the bottle of EGF freeze-dried powder, and mix well to form 2.5mL of EGF solution.

[0033] 3. Add the PRP prepared in Example 2 to the EGF solution to obtain liquid A; resuspend the umbilical cord mesenchymal stem cells prepared in Example 1 with physiological saline to obtain the umbilical cord mesenchymal stem cell suspension, and...

Embodiment 4

[0036] Embodiment 4 facial anti-wrinkle effect evaluation

[0037] Select 120 healthy adults (half male and half male) with obvious wrinkles on the face, aged 40 to 60 years old; randomly divided into 4 groups, including 3 groups of control groups and 1 group of experimental groups, and then the preparations shown in Table 3 Inject into the deep dermis where there are many facial wrinkles respectively, and evaluate the anti-wrinkle effect after 4 weeks. The evaluation indicators are: the cosmetic effect is scored according to the degree of facial wrinkle repair, the better the repair, the higher the score; the maintenance time is the time span from the appearance of the cosmetic effect to the loss of the cosmetic effect. As shown in the results in Table 4, the wrinkle repair effect and maintenance time of Example 1 are much higher than those of the control groups 1 to 3, showing its good cosmetic effect.

[0038] table 3

[0039] group

Component

Control g...

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Abstract

The invention belongs to the field of cosmetics, and in particular relates to a stem cell composition and a face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing. The stem cell composition provided by the invention consists of umbilical cord mesenchymal stem cells, nicotinamide, PRP and EGF; and on the basis of reasonable compatibility and a synergistic effect, the stem cell composition provided by the invention integrates functions of resisting wrinkles, whitening and moisturizing and the stem cell composition is longer in lasting time. The face young-keeping and beauty-maintaining preparation for resisting wrinkles, whitening and moisturizing, which is prepared from the stem cell composition, can remove face wrinkles, improve skin texture and brighten complexion, and the preparation is good in repair effect and long in lasting time.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a stem cell composition and an anti-wrinkle, whitening and water-replenishing cosmetic preparation for facial rejuvenation. Background technique [0002] Face rejuvenation refers to various means and methods that can restore a youthful appearance to the aging face. Facial aging is the result of common changes in the soft and hard tissues of the body and the face / neck. The main manifestations are: thin and dry facial skin, weakened skin elasticity, skin pigmentation, dull and uneven skin tone, increased wrinkles, and reduced subcutaneous fat tissue. Local accumulation, sagging caused by loose supporting structures, muscle atrophy. Facial aging is closely related to factors such as physical fitness, genetic factors, living environment, psychological emotions, working environment, nutritional status, disease, and local skin care. The average person begins to show signs of agin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/67A61K8/64A61K8/98A61Q19/02A61Q19/00A61Q19/08C12N5/0775
CPCA61K8/99A61K8/64A61K8/675A61K8/983A61K2800/91A61Q19/00A61Q19/02A61Q19/08C12N5/0665C12N2509/00
Inventor 马颖马铎阮雯莉
Owner GUANGZHOU ZISHENG BIOLOGICAL TECH CO LTD
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