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A kind of fibronectin freeze-dried powder preparation and preparation method thereof

A technology of fibronectin and freeze-dried powder, which is applied in skin care preparations, pharmaceutical formulas, and cosmetic preparations, etc., can solve the problems of few freeze-dried fibronectin powder and related preparations, and no further analysis of efficacy, etc., to achieve The effect of good cell morphology and structure, maintenance of cell morphology and structure, and improvement of cell fusion efficiency

Active Publication Date: 2022-04-19
湖南本美生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, there are few studies on lyophilized powder containing fibronectin and related preparations, and most of them have not further analyzed its effect on cell activity and other effects such as convenient water content during application.

Method used

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  • A kind of fibronectin freeze-dried powder preparation and preparation method thereof
  • A kind of fibronectin freeze-dried powder preparation and preparation method thereof
  • A kind of fibronectin freeze-dried powder preparation and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0034] A fibronectin lyophilized powder preparation, comprising a fibronectin lyophilized powder and a vehicle;

[0035] Among them, the fibronectin freeze-dried powder is calculated in parts by weight, including: 28 parts of fibronectin, 4 parts of mannitol, 1.5 parts of brown algae extract, 2 parts of Phaeodactylum tricornutum extract, 0.6 part of pH regulator, 0.2 parts buffer and 63.7 parts water.

[0036] The medium liquid comprises: 0.5 parts of carboxymethyl chitosan, 3 parts of peony extract, 6 parts of chlorella extract, 4 parts of moisturizing agent, 0.15 part of chelating agent and 86.35 parts of water in parts by weight.

[0037] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0038] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extract, st...

Embodiment 2

[0053] A fibronectin lyophilized powder preparation, comprising a fibronectin lyophilized powder and a vehicle;

[0054] Among them, the fibronectin freeze-dried powder includes: 36 parts of fibronectin, 7 parts of mannitol, 0.5 part of brown algae extract, 0.5 part of Phaeodactylum tricornutum extract, 0.3 part of pH regulator, 0.1 part of buffer and 55.6 parts water.

[0055] The vehicle comprises, in parts by weight, 1.5 parts of carboxymethyl chitosan, 7 parts of peony extract, 8.5 parts of chlorella extract, 2 parts of moisturizing agent, 0.1 part of chelating agent and 80.9 parts of water.

[0056] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0057] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extract, stir evenly to ensure complete dissoluti...

Embodiment 3

[0069] A fibronectin lyophilized powder preparation, comprising a fibronectin lyophilized powder and a vehicle;

[0070] Among them, the fibronectin freeze-dried powder includes: 34 parts of fibronectin, 6 parts of mannitol, 1 part of brown algae extract, 1 part of Phaeodactylum tricornutum extract, 0.44 parts of pH regulator, 0.13 parts buffer and 57.43 parts water.

[0071] The medium solution is calculated in parts by weight, including: 1 part of carboxymethyl chitosan, 5 parts of peony extract, 7 parts of chlorella extract, 3 parts of moisturizing agent, 0.1 part of chelating agent and 83.9 parts of water.

[0072] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0073] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extract, stir evenly to ensure com...

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Abstract

The invention provides a fibronectin freeze-dried powder preparation and a preparation method thereof, and relates to the technical field of cosmetics. The fibronectin freeze-dried powder preparation includes fibronectin freeze-dried powder and enzyme liquid; wherein, the fibronectin freeze-dried powder Contains: Fibronectin, Mannitol, Brown Algae Extract, Phaeodactylum Tricornutum Extract, pH Adjuster, Buffer and Water. The freeze-dried powder preparation has high nutrition and high activity and can be repaired intensively. The biological transdermal absorption technology can make the skin absorption efficiency more than 20 times, and can effectively improve the skin moisture content and cell activity.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a fibronectin freeze-dried powder preparation and a preparation method thereof. Background technique [0002] Freeze-dried powder is a sterile powder injection made by freezing the medicinal liquid into a solid state in a sterile environment, sublimating and drying the water in a vacuum, because it can well retain the active ingredients and has deep penetration and fast absorption. Therefore, it is widely used in the fields of medicine and cosmetics. In the past, EGF was often added to freeze-dried powder due to its strong repairing ability. However, after EGF cannot be used as a cosmetic raw material, how to find a suitable substitute has become a more concerned issue at present. Fibronectin is a macromolecular outer membrane protein present on the surface of various animal cells. It is the main non-collagenous glycoprotein in the extracellular matrix and basement membrane. I...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9794A61K8/34A61K8/64A61K8/73A61K8/9711A61K8/9722A61Q19/00
CPCA61K8/9711A61K8/64A61K8/345A61K8/9722A61K8/9789A61K8/9794A61K8/735A61Q19/00A61K2800/5922A61K2800/84
Inventor 简经红
Owner 湖南本美生物科技有限公司
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