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Drug clinical comprehensive evaluation method based on real world

A comprehensive evaluation and real-world technology, applied in special data processing applications, instruments, electrical digital data processing, etc., can solve problems such as limited evidence for evaluating drugs, and achieve a system that is easy to understand and apply, suitable for popularization and application, and rigorous in mathematical principles Effect

Pending Publication Date: 2017-12-15
CHILDRENS HOSPITAL OF FUDAN UNIV
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AI Technical Summary

Problems solved by technology

[0004] Based on the technical problems existing in the background technology, the present invention proposes a comprehensive clinical evaluation method for drugs based on the real world. Some use evidence-based medicine to evaluate the limited evidence of medicines

Method used

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  • Drug clinical comprehensive evaluation method based on real world
  • Drug clinical comprehensive evaluation method based on real world
  • Drug clinical comprehensive evaluation method based on real world

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Select penicillins, penicillin and amoxicillin-clavulanate potassium, first-generation cephalexin and cefazolin, third-generation ceftazidime and ceftriaxone, antifungal drugs fluconazole and amphotericin B, antiviral drugs Acyclovir and ganciclovir, antipyretic and analgesic drugs ibuprofen and acetaminophen are used as examples to illustrate the comprehensive evaluation system for children's clinical medication.

[0035] The evaluation method flow is as attached to the manual Figure 7 Shown:

[0036] Select specific indicators for each module and ask experts to score, determine the weight of each module through the Delphi method, and then express the safety, effectiveness, compliance, and economic indicators with specific data, and adopt a scoring system (0-5 points system) to score indicators.

[0037] Table 1 Grading and scoring of effectiveness indicators

[0038]

[0039] Table 2 Description of safety indicators

[0040]

[0041] Table 3 Economic indica...

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Abstract

The invention discloses a drug clinical comprehensive evaluation method based on the real world. The method includes the steps of establishing an evaluation object, establishing an index system, determining an index weight, establishing an evaluation methodology variable model, analyzing and summarizing results and the like. According to the method, a linear algebra method is used in the operation process, the mathematical principle is rigorous, the operation method is easy to understand and apply, system analysis and calculation are simplified, decisions are kept consistent easily, and the method is applicable to qualitative decision analysis or qualitative and quantitative decision analysis, convenient and rapid to use, easy to operate and suitable for application and popularization.

Description

technical field [0001] The present invention relates to the technical field of medical big data evaluation, in particular to a method for clinical comprehensive evaluation of drugs based on the real world. Background technique [0002] With the development of medical informatization, a large amount of digitized data is generated in the process of medical services, health care and health management, forming medical big data. Using clinical big data to carry out real-world clinical research, the development of these big data can realize smart medical care, that is, to realize the convenience of patients seeking medical treatment, the automation of disease diagnosis, and the informatization of medical care. Medical big data, that is, clinical medical big data, usually includes the following six aspects: (1) hospital medical big data mainly including electronic health records, electronic medical records, medical images, inspections, etc.; (2) gene sequences, proteomes and other ...

Claims

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Application Information

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IPC IPC(8): G06F19/00
Inventor 李智平卢金淼李琴
Owner CHILDRENS HOSPITAL OF FUDAN UNIV
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