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Compound pharmaceutical composition for treatment of respiratory diseases and use thereof

A composition and respiratory technology, applied in drug combination, respiratory system diseases, antibacterial drugs, etc., can solve problems such as difficult and effective treatment

Active Publication Date: 2017-12-22
佛山市第五人民医院 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, respiratory diseases involve various leukocytes, cytokines, and inflammatory mediators isolated from them, so it is difficult to achieve effective treatment with single-component compounds

Method used

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  • Compound pharmaceutical composition for treatment of respiratory diseases and use thereof
  • Compound pharmaceutical composition for treatment of respiratory diseases and use thereof
  • Compound pharmaceutical composition for treatment of respiratory diseases and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: compound combination medicine 1

[0023] Mix emodin and genistein in a weight ratio of 1:1; for uniform mixing, add about 2 to 3 times the weight of water to the combined extract, and then concentrate it under vacuum at 50-60°C; then, An equal amount of water is added to the obtained concentrate again to uniformly suspend it, and the obtained suspension is freeze-dried to prepare the compound combination drug 1 in powder form.

Embodiment 2

[0024] Embodiment 2: compound combination medicine 2

[0025] Mix emodin and genistein at a weight ratio of 1:5; for uniform mixing, add about 2 to 3 times the weight of water to the combined extract, and then concentrate it under vacuum at 50-60°C; then, An equal amount of water is added to the obtained concentrate again to uniformly suspend it, and the obtained suspension is freeze-dried to prepare the compound combination drug 2 in powder form.

Embodiment 3

[0026] Embodiment 3: compound combination medicine 3

[0027] Emodin and genistein were mixed at a weight ratio of 1:10; for uniform mixing, about 2 to 3 times the weight of water was added to the combined extract, which was then concentrated under vacuum at 50-60°C; then, An equal amount of water is added to the obtained concentrate again to uniformly suspend it, and the obtained suspension is freeze-dried to prepare the compound combination drug 3 in powder form.

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PUM

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Abstract

Belonging to the field of natural drugs, the invention discloses a compound pharmaceutical composition for treatment of respiratory diseases and use thereof. The active components of the compound pharmaceutical composition include emodin and genistein in a weight ratio of 1:1-1:10. The compound pharmaceutical composition can be used for preparation of drugs preventing or treating respiratory diseases including common cough, common expectoration, emphysema with cough and phlegm, bronchitis, asthma, chronic or acute bronchoconstriction, wheezing baby syndrome, chronic obstructive pulmonary disease, bronchial adenoma, solitary pulmonary nodules, pulmonary tuberculosis, empyema, lung abscess, common cold, influenza and pulmonary histiocytosis.

Description

technical field [0001] The invention belongs to the field of natural medicines, in particular to a compound medicinal composition for treating respiratory diseases and its application. Background technique [0002] Cough and sputum are caused by physical or chemical factors - such as cold air, foreign substances including pathogenic microorganisms, air pollutants, allergens, etc. - and can be classified according to the cause as follows: 1) If the larynx, trachea, bronchi , pharynx, paranasal sinuses, and diaphragm are stimulated by physical and chemical factors, and the stimulation will be transmitted to the cough center of the medulla, thereby generating a cough reflex; 2) If the parasympathetic nervous system is stimulated by physical or chemical factors Activation, the smooth muscle of the bronchus contracts, and symptoms such as bronchospasm and bronchoconstriction may appear; 3) Physical or chemical factors release inflammatory mediators, etc. from mast cells. Removal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/122A61K31/352A61P11/00A61P11/14A61P11/06A61P31/06A61P31/16
CPCA61K31/122A61K31/352A61K2300/00
Inventor 陈钢黄文柱刘连王志军刘腾彭咏波严文
Owner 佛山市第五人民医院
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