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Traditional Chinese medicine composition for treating lumbar disc herniation with kidney deficiency and blood stasis and a preparation method thereof

A technology for lumbar disc herniation, kidney deficiency and blood stasis, applied in the direction of drug combinations, pharmaceutical formulas, active ingredients of hydroxyl compounds, etc., can solve the problems of differences in curative effect indicators, no significant statistical significance, etc., to improve waist and knee soreness and fatigue, and relieve waist pain. Leg pain, effect of improving gait

Inactive Publication Date: 2017-12-22
CHANGCHUN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many studies suggest that the long-term efficacy of the two therapies is similar, and there is no statistically significant difference in the main efficacy indicators

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 25 parts of Rehmannia glutinosa, 20 parts of Luniancao, 18 parts of Epimedium, 18 parts of oysters, 9 parts of Clematis, 9 parts of roasted dog bones, 9 parts of Poria cocos, 9 parts of Siberia chinensis, and 1.1 parts of borneol.

[0016] For the above nine flavors, borneol is ground into fine powder; for the other eight flavors such as Rehmannia glutinosa, add water and decoct twice for 2 hours each time, combine the decoction, filter, and measure the relative density of 1.05 when the filtrate is concentrated to 60°C. The alcohol content reaches 65%, put it aside for 16 hours, filter, recover the ethanol from the filtrate and concentrate it to 80°C to measure a thick paste with a relative density of 1.15, dry it under reduced pressure, crush it into fine powder, sieve, mix well, add borneol fine powder, mix uniform.

Embodiment 2

[0018] 30 parts of Rehmannia glutinosa, 25 parts of Luniancao, 20 parts of Epimedium, 20 parts of oysters, 10 parts of Clematis, 10 parts of roasted dog bones, 10 parts of Poria cocos, 10 parts of Siberia chinensis, 1.2 parts of borneol;

[0019] For the above nine flavors, borneol is ground into fine powder; for the other eight flavors such as Rehmannia glutinosa, add water and decoct 3 times, 1.5 hours each time, combine the decoction, filter, and measure the relative density of 1.08 when the filtrate is concentrated to 60°C. The amount of alcohol reaches 70%, put it aside for 24 hours, filter, recover the ethanol from the filtrate and concentrate it to 80 ° C to measure the thick paste with a relative density of 1.20, dry it under reduced pressure, crush it into fine powder, sieve, mix well, add borneol fine powder, mix Mix evenly, pack into capsules, and get ready.

Embodiment 3

[0021] 35 parts of Rehmannia glutinosa, 30 parts of Luniancao, 22 parts of Epimedium, 22 parts of oysters, 11 parts of Clematis, 11 parts of roasted dog bones, 11 parts of Poria cocos, 11 parts of Herba chinensis, 1.3 parts of borneol;

[0022] For the above nine flavors, borneol is ground into fine powder; for the other eight flavors such as Rehmannia glutinosa, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, and measure the relative density of 1.10 when the filtrate is concentrated to 60 ° C. The alcohol content reaches 75%, put it aside for 32 hours, filter, recover the ethanol from the filtrate and concentrate it to 80°C to measure a thick paste with a relative density of 1.25, dry it under reduced pressure, crush it into fine powder, sieve, mix well, add borneol fine powder, mix uniform.

[0023] The present invention treats the clinical research of lumbar intervertebral disc herniation.

[0024] The present invention is hereinafter referre...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating lumbar disc herniation with kidney deficiency and blood stasis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25-35 parts of rehmannia glutinosa, 20-30 parts of herba pyrolae, 18-22 parts of epimedium, 18-22 parts of oyster, 9-11 parts of radix clematidis, 9-11 parts of sun-cured dog bone, 9-11 parts of tuckahoe, 9-11 parts of siegesbeckia pubescens, 1.1-1.3 parts of borneol. The composition has the advantages of clearing and activating the channels and collaterals, removing stasis and relieving pain, is mainly used for treating lumbar spinal stenosis, lumbar disc herniation, and sciatica, and is developed to be a preparation in the affiliated hospital of Changchun University of Chinese medicine for mainly treating waist and leg pain caused by lumbar spinal stenosis, and after clinical application of the composition for many years, a large number of patients with lumbar disc herniation after administration show good therapeutic effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and a preparation method for treating lumbar intervertebral disc herniation. Background technique [0002] Lumbar disc herniation (lumbar disc herniation, LDH) refers to the degenerative change, injury and strain of the lumbar intervertebral disc, resulting in the rupture of the fibrous annulus or cartilage plate of the lumbar intervertebral disc, and the herniation of the nucleus pulposus stimulates or compresses the dural sac, nerve roots, Cauda equina nerve, causing a clinical syndrome characterized by lumbago and leg pain and neurological dysfunction, is a common and frequently-occurring disease in orthopedic clinics. Because lumbago and leg pain often show effect repeatedly, seriously affect patient's work, life etc. Many international low back pain surveys have found that the prevalence of low back pain is 15% to 30%. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P19/08A61P25/02A61P29/00A61K31/045A61K35/32A61K35/618
CPCA61K36/804A61K31/045A61K35/32A61K35/618A61K36/076A61K36/185A61K36/28A61K36/296A61K36/716A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘钟华赵文海于秀华闻辉史野
Owner CHANGCHUN UNIV OF CHINESE MEDICINE
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