Disinfectant for skin and mucous membrane and preparation method thereof

Abstract

The invention discloses a disinfectant for a skin and mucous membrane and a preparation method thereof. The disinfectant for the skin and mucous membrane is prepared from refined iodine, nonylphenol polyoxyethylene ether and deionized water, wherein the addition weight ratio of the refined iodine to the nonylphenol polyoxyethylene ether to the deionized water is (0.25 to 0.45) to (1.5 to 3.0) to (94.5 to 102). The preparation method comprises the following steps of adding the refined iodine and the nonylphenol polyoxyethylene ether into a closed reactor respectively, agitating at normal temperature and under normal pressure to carry out synthetic reaction for a reaction time of 6 to 9 hours, so as to obtain a solution A, taking and putting the solution A into a mixing tank, adding the deionized water, agitating for 15 to 30 minutes, and standing, so as to obtain the disinfectant for the skin and mucous membrane. The disinfectant for the skin and mucous membrane, which is obtained by the preparation method, can be used for effectively killing an enteric pathogenic bacterium, a pyogenic coccus, pathogenic yeast and a common infectious bacterium, and moreover, has the characteristicsof being high in safety and high in stability.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a skin and mucous membrane disinfectant and a preparation method thereof. Background technique [0002] Disinfection is the process of removing or killing various pathogenic microorganisms in the external environment except bacterial spores. Skin and mucous membrane disinfectant is mainly used for disinfection of human skin and mucous membranes, and can quickly kill hepatitis A and B viruses, Escherichia coli, and dysentery Bacillus, Pseudomonas aeruginosa, Staphylococcus, etc., can be used as a scrub agent for surgical operations, a rinse agent for decubitus ulcers, etc., and has dual functions of disinfection and cleaning. [0003] Commonly used skin and mucous membrane disinfectants include ethanol, povidone iodine, chlorhexidine, quaternary ammonium compounds, triclosan, etc. [0004] Ethanol can coagulate and denature bacterial proteins and play a bactericidal effect. Howe...

AI Technical Summary

Problems solved by technology

Triclosan has a certain antibacterial spectrum, but it is biased towards antibacterial

Triclosan has some activity against mycobacteria and candida, but less activity against filamentous fungi