Head-mounted ultrasound transmission device

Abstract

The present invention is suitable for the field of ultrasound neural stimulation research technology, and discloses a head-mounted ultrasound transmission device. The device comprises a pedestal capable of being arranged on a skull of an experimental animal and a top cover connected with the pedestal, the pedestal is internally provided with an inner cavity configured to hold a couplant, and the top cover is connected with an ultrasound transducer having a working surface facing the bottom portion of the inner cavity; and the device also comprises a fixing device configured to fix the pedestalat the skull of the experimental animal, the fixing device comprises a skull connection piece which has a front end capable of being embedded into the skull of the experimental animal, and the pedestal is applied to the skull of the experimental animal and is directly connected with or connected with the fixing device through a binder. The head-mounted ultrasound transmission device can achieve accurate, controllable and repeatable ultrasound stimulation at an implementation position of a brain of an unrestrained experimental animal, is suitable for development of animal experiments related to memory such as feeling, emotion, cognition and the like, and is good in implementation effect.

Description

technical field [0001] The invention belongs to the technical field of ultrasonic nerve stimulation research, in particular to a head-mounted ultrasonic conduction device. Background technique [0002] Nerve stimulation and neuromodulation refer to the process of acting on the living nervous system (such as organisms, organs, tissues, cells, etc.) and causing responses by using physical stimuli such as electricity, light, sound, heat, cold, or machinery, as well as chemical stimuli. According to the effect of stimulation regulation, it can be divided into excitatory stimulation that makes function display or enhancement and inhibitory stimulation that makes function disappear or weaken. By stimulating and regulating neural activity, it is helpful for the study of nervous system diseases and mental diseases, and it is also a basic means for studying the human brain's feelings, actions and cognitive functions. [0003] Ultrasound stimulation is an ancient and emerging non-inv...

AI Technical Summary

Problems solved by technology

However, how to design a reasonable structure to achieve a reliable connection between the ultrasonic transducer and the skull and ensure that the ultrasonic energy can be effectively transmitted to the inside of the skull is an extremely critical technology for the entire ultrasonic stimulation system, and the above patents do not propose a feasible solution for this

[0008] In the prior art, ultrasonic nerve stimulation technology uses a large and heavy ultrasonic probe to achieve ultrasonic stimulation, and the stimulated animal needs to be anesthetized and its head needs to be fixed, so the above-mentioned ultrasonic stimulation is not suitable for Conduct animal experiments related to sensation, emotion, cognition and memory

Moreover, the existing wearable ultrasonic stimulation solutions (documents with application numbers 201610326489.0, 201610327257.7, and 201710138442.6) do not clearly propose how to reliably fix the ultrasonic transducer on the skull or simply mention the use of sealing tape for fixation. Way

[0009] To sum up, in the prior art, aiming at the stimulation device for small animals in the field of ultrasonic nerve stimulation technology, it is difficult to accurately control and repeat the stimulation to small movements that are awake and free to move, and there are problems such as poor implementation effect

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