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Traditional Chinese medicine preparation for treating chronic kidney disease proteinuria and preparation method thereof

A technology for chronic kidney disease and traditional Chinese medicine preparation, applied in the field of traditional Chinese medicine, can solve problems such as poor curative effect of kidney yin deficiency syndrome, and achieve the effects of significant curative effect, relieving yin deficiency and fire exuberance, and remarkable effect.

Active Publication Date: 2018-02-23
湖北省中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a Chinese medicine preparation for treating proteinuria in chronic kidney disease with a significant curative effect on kidney yin deficiency and its preparation method in view of the problem of poor curative effect on kidney yin deficiency existing in the prior art

Method used

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  • Traditional Chinese medicine preparation for treating chronic kidney disease proteinuria and preparation method thereof
  • Traditional Chinese medicine preparation for treating chronic kidney disease proteinuria and preparation method thereof

Examples

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preparation example Construction

[0019] A preparation method of a traditional Chinese medicine preparation for the treatment of chronic kidney disease proteinuria includes the following steps in sequence:

[0020] Decoction: Mix the raw materials in the required proportions, add water and decoct for several times to obtain the decoction, wherein the weight of the water added is 8-10 times the sum of the weight of the raw materials after the amomum is packaged separately;

[0021] Preparation of dosage form: first combine the decoction and filter, then take the filtrate and let stand overnight, take the supernatant, and then concentrate the supernatant under reduced pressure to obtain a concentrate, then add auxiliary materials for granulation, drying, and granulation OK.

[0022] In the decoction step, each decoction time is 1-2h.

[0023] The principle of the present invention is explained as follows:

[0024] Traditional Chinese medicine treatment of chronic kidney disease proteinuria usually starts with the kidneys...

Embodiment 1

[0027] A traditional Chinese medicine preparation for the treatment of proteinuria in chronic kidney disease. The raw material composition and weight ratio of the traditional Chinese medicine preparation are: Codonopsis 30, Asparagus 10, Rehmannia 15, Phellodendron amurense 10, Shengdi 15, Amomum 5, and licorice 10;

[0028] When preparing, follow the steps below:

[0029] Decoction: mix the ingredients according to the required ratio, add water and decoc 2 times to obtain the decoction. The weight of the water added is 9 times the sum of the weight of the ingredients. The cooking time is 1h;

[0030] Preparation of dosage form: first combine the decoction and filter, then take the filtrate and let stand overnight, take the supernatant, and then concentrate the supernatant under reduced pressure to obtain a concentrate, then add auxiliary materials for granulation, drying, and granulation OK.

Embodiment 2

[0032] The steps are the same as in Example 1, the difference is:

[0033] The raw material composition and weight ratio of the traditional Chinese medicine preparation are: Codonopsis 15, Asparagus 6, Rehmannia 10, Cork 10, Shengdi 10, Amomum villosum 5, and Licorice 10;

[0034] In the decoction step, the added weight of water is 10 times the sum of the weight of each raw material, and the time of each decoction is 1.5 hours.

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic kidney disease proteinuria, which comprises the following raw materials in parts by weight: 15-30 parts of codonopsis pilosula, 6-15 parts of radix asparagi, 10-15 parts of prepared rehmannia root, 5-10 parts of bark of Chinese corktree, 10-15 parts of rehmannia root, 3-5 parts of villous amomum fruit and 3-10parts of licorice root. The preparation method comprises the steps of decocting the raw materials in water according to required proportions first, carrying out reduced-pressure concentration after filtering, then adding adjuvants, and carrying out granulating and drying. The traditional Chinese medicine preparation not only has an obvious curative effect on kidney yin deficiency syndrome, but also can effectively relieve the symptom of hyperactivity of fire due to yin deficiency.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine preparation for the treatment of chronic kidney disease proteinuria and a preparation method thereof. The effect of proteinuria is more significant for kidney yin deficiency syndrome. Background technique [0002] Proteinuria is caused by the deposition of immune complexes in the glomerular capillaries due to various reasons, which increases the permeability of the glomerular filtration membrane, and a large amount of albumin leaks out, which exceeds the absorption capacity of the renal tubules and is excreted with urine. Prolonged or repeated proteinuria not only aggravates renal tubule ischemia, hypoxia, and glomerular sclerosis, but eventually leads to atrophy of renal tubules and glomeruli, leading to renal failure. [0003] Chronic kidney disease (CKD) has become a global public health problem, with more than 500 million CKD pat...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P13/12
CPCA61K9/0095A61K36/344A61K36/484A61K36/756A61K36/804A61K36/8965A61K36/9064A61K2236/331A61K2236/39A61K2300/00
Inventor 巴元明
Owner 湖北省中医院
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