Modular system and modular method for tumor gene detection assembly line

Abstract

The invention discloses a modular system and a modular method for a tumor gene detection assembly line. According to the present invention, partial or all modules such as a leucocyte and plasma separation module, a pathological examination module, a DNA extraction module, a DNA fragmentation module, a library construction module, a DNA capture module, an on-machine sequencing module and the like are centralized, and are subjected to permutation and combination to form the modular system, wherein the selection and permutation and combination mode of the modules is related to the type of detected samples, and the setting of the conditions and the states in various modules for forming the modular system of the tumor gene detection assembly line is related to the type of detected samples; themodular method comprises: preparing and using the connection relationships among the modules in a centralized manner, and setting the conditions and the states in the modules, wherein the modules of the modular system for the tumor gene detection assembly line are prepared according to the type of detected samples; and with the system and the method, the practicability and the flexibility of the tumor gene detection assembly line operation are enhanced, and the tumor gene detection assembly line can well meet the frequently changing production demands.

Description

technical field [0001] The invention relates to a tumor gene detection system, in particular to a modular system and method for a tumor gene detection pipeline. Background technique [0002] At present, the technology of tumor gene detection is becoming more and more mature, and the technology of tumor gene detection is gradually moving from the laboratory to commercialization and engineering. Especially in the aspect of personalized treatment of tumors, tumor gene detection plays an important role. In the process of moving from a scientific research laboratory to commercialization and engineering, a major challenge for tumor genetic testing is how to standardize the technical steps in the laboratory to improve the efficiency and quality of tumor genetic testing pipeline operations. [0003] A gene is a functional segment of a DNA molecule and the basic unit of genetic information. Tumor gene detection is a technology for tumor detection by DNA through blood, other body flu...

AI Technical Summary

Problems solved by technology

[0007] Second, in the experimental process within each process step, there are different states that require different post-processing methods

The workflow can handle the automatic flow of each experimental process. However, the definition of these states lacks a standardized classification. The staff of the tumor gene detection pipeline cannot clearly understand the meaning of different states, and there is a lack of standard corresponding processing for these different states. method

[0008] Third, the experimental conditions involved in each process step are different, and specific experimental conditions need to be set for each process step, or the setting of experimental conditions should be changed, so the setting of experimental conditions in each process step is usually time-consuming and labor-intensive , unable to quickly respond to changes in the experimental process and conditions in the process steps

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