Method for preparing honeysuckle essential oil-beta-cyclodextrin inclusion compound

A technology of cyclodextrin inclusion complex and honeysuckle essential oil, which is applied in the preparation of tobacco, medical preparations containing active ingredients, food science and other directions, can solve the problems of limited application, easy volatilization, poor stability, etc. The effect of improving stability and facilitating wide application

Inactive Publication Date: 2018-03-16
刘晓霞
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Honeysuckle essential oil is extremely volatile and has poor stability, which seriously limits its application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation method of a honeysuckle essential oil-β-cyclodextrin inclusion compound of the present invention comprises the following preparation steps:

[0018] (1) Take 500g of fresh flower buds of honeysuckle, put them in a 10L round bottom flask, add 5L of deionized water, and use steam distillation to collect the distillate, about 1L;

[0019] (2) Add 35g / L NaCl to the distillate, dissolve it, let it stand for 1h, extract it with an equal volume of distilled water and ether, dry the extract with anhydrous sodium sulfate, distill it under reduced pressure to obtain the light yellow honeysuckle essential oil, place it in 5 ℃ refrigerator for use;

[0020] (3) Weigh a certain amount of honeysuckle essential oil, dissolve it in a small amount of absolute ethanol, slowly drop it into 100 mL of β-cyclodextrin saturated solution at the same temperature at a certain temperature, and stir at 300r / min for a certain period of time After that, take it out and cool it down ...

Embodiment 2

[0026] The preparation method of a honeysuckle essential oil-β-cyclodextrin inclusion compound of the present invention comprises the following preparation steps:

[0027] (1) Take 500g of fresh flower buds of honeysuckle, put them in a 10L round bottom flask, add 5L of deionized water, and use steam distillation to collect the distillate, about 1L;

[0028] (2) Add 35g / L NaCl to the distillate, dissolve it, let it stand for 1h, extract it with an equal volume of distilled water and ether, dry the extract with anhydrous sodium sulfate, distill it under reduced pressure to obtain the light yellow honeysuckle essential oil, place it in 5 ℃ refrigerator for use;

[0029] (3) Weigh a certain amount of honeysuckle essential oil, dissolve it in a small amount of absolute ethanol, slowly drop it into 100 mL of β-cyclodextrin saturated solution at the same temperature at a certain temperature, and stir at 300r / min for a certain period of time After that, take it out and cool it down ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a preparation method of honeysuckle essential oil-β-cyclodextrin inclusion compound, which comprises the following preparation steps: take 500g of honeysuckle fresh flower buds, place them in a 10L round bottom flask, add 5L of deionized water, and steam distill method, collect the distillate, about 1 L; a kind of honeysuckle essential oil-β-cyclodextrin inclusion compound prepared by the method of the present invention has a light honeysuckle essential oil fragrance, and the inclusion rate of honeysuckle essential oil can reach 68.95%. Through the preparation process, the volatilization rate of the honeysuckle essential oil is significantly reduced, the stability of the honeysuckle essential oil is improved, and the liquid honeysuckle essential oil is solidified, thereby facilitating its wide application.

Description

technical field [0001] The invention relates to a preparation method of honeysuckle essential oil-beta-cyclodextrin inclusion compound. Background technique [0002] Honeysuckle is the flower bud of Lonicera Lonicera, which contains various natural active ingredients such as chlorogenic acid, luteolin and honeysuckle essential oil. It is the main formula ingredient of various preparations such as Yinhuang Granules, Yinhuang Oral Liquid and Chaihuang Oral Liquid. Honeysuckle essential oil is a light yellow oily liquid prepared from honeysuckle flower buds by lipophilic organic solvent extraction, steam distillation, supercritical fluid extraction or molecular distillation. It is widely used in cigarettes, fragrances and daily cosmetics. Honeysuckle essential oil is extremely volatile and has poor stability, which seriously limits its application. β-cyclodextrin is a cylindrical molecule composed of 7 glucose groups connected by 1,4-glycosidic bonds. It has a ring-shaped ho...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/61A61K8/92A61K8/73A24B3/12A23L33/115A23L33/125
CPCA61K8/922A23L33/115A23L33/125A23V2002/00A24B3/12A61K8/738A61K2236/331A23V2250/21A23V2250/5112
Inventor 刘晓霞
Owner 刘晓霞
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap