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Artery medicine elution stent made of bioabsorbable material and preparing method of artery medicine elution stent

A technology for eluting stents and materials, which is applied in the field of vascular stents and can solve problems such as potential generation, microthrombi, and uneven stent surfaces.

Inactive Publication Date: 2018-03-23
GENERAL HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Moreover, the surface of traditional coated stents is very rough, and when implanted in the body, electric potential and microthrombus can be generated locally.

Method used

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  • Artery medicine elution stent made of bioabsorbable material and preparing method of artery medicine elution stent
  • Artery medicine elution stent made of bioabsorbable material and preparing method of artery medicine elution stent
  • Artery medicine elution stent made of bioabsorbable material and preparing method of artery medicine elution stent

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Embodiment Construction

[0037] Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus their detailed descriptions will be omitted.

[0038] The embodiment of the present invention provides an arterial drug-eluting stent made of bioabsorbable material. Of course, those skilled in the art should understand that this stent technology can also be transformed and applied to cardiovascular, peripheral blood vessels, nerve conduits, intestines, and bile ducts. , urethral and bone repair / reconstruction applications, etc.

[0039] In the arterial drug-eluting stent...

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Abstract

The invention relates to an intravascular stent technology, and discloses an artery medicine elution stent made of a bioabsorbable material and preparing method of the artery medicine elution stent. The stent comprises multiple stent beams, and a stent body is made of bioabsorbable water soluble resin or a water soluble polymer; in the aspect of the cross sections of the stent beams, the stent comprises a solid structural body and a medicine carrier of a porous structure, the medicine carrier is located at the side, facing the blood vessel wall, of the stent and comprises a surface layer of the outer surface and the porous structure inside, the surface layer is provided with multiple releasing holes, and the stent body is integrally formed according to a 3D printing technology. By means ofthe 3D printing technology, the porous structural design of the stent can be achieved, and an innovative thought of medicine carrying inside the stent can be completed. Restenosis and thrombus in thestent can be effectively prevented from being caused due to a stent technological defect.

Description

technical field [0001] The present invention generally relates to a vascular stent technology, in particular to a novel arterial drug-eluting stent of bioabsorbable material and a preparation method thereof. Background technique [0002] Since 1987, when Sigwart et al. used intravascular metal stents for coronary arteries for the first time, it has provided a good way for the treatment of vascular occlusion diseases. However, in-stent restenosis and in-stent thrombosis have always affected the The main reason for the efficacy of percutaneous coronary intervention (PCI). The main mechanism of in-stent restenosis is the hyperplasia of vascular intima and the delay of vascular endothelialization. Therefore, the prevention and treatment of in-stent restenosis is mainly to promote the rapid repair of vascular endothelium and inhibit the excessive proliferation of smooth muscle cells. [0003] The currently widely used coronary artery drug-eluting stent (DES) carries drugs throug...

Claims

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Application Information

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IPC IPC(8): A61F2/07A61F2/89A61L31/06A61L31/04A61L31/02A61L31/14A61L31/16
CPCA61F2/07A61F2/89A61F2002/821A61F2240/001A61F2250/0067A61L31/022A61L31/048A61L31/06A61L31/14A61L31/146A61L31/148A61L31/16A61L2300/416A61L2300/602C08L67/04C08L33/02
Inventor 胡鸢白静冯宏启白洁金昕樊明浩白云
Owner GENERAL HOSPITAL OF PLA
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