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Natural extract composition having oxidation resistant effect, preparation and application

A technology of natural extracts and anti-oxidation effects, which is applied in the direction of drug combinations, medical preparations containing active ingredients, anti-toxic agents, etc., can solve problems such as the decline of anti-oxidation performance, and achieve the purpose of inhibiting lipid peroxidation and regulating anti-oxidation. Enzyme activity, defense-enhancing effect

Inactive Publication Date: 2018-03-27
JIANGSU DEHE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Su Y.L. investigated the antioxidant capacity of theaflavins, catechins and their derivatives in Canola oil, and found that catechins had stronger antioxidant properties than theaflavins at a concentration of 0.5mmol / L. and EGCG have the strongest performance, both of which are far stronger than the antioxidant effect of BHT, but the methylation of the 3' hydroxyl group will lead to a significant decline in the antioxidant performance

Method used

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  • Natural extract composition having oxidation resistant effect, preparation and application
  • Natural extract composition having oxidation resistant effect, preparation and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Embodiment 1: hard capsule

[0054] (1), taking materials: get theaflavin 50g, astaxanthin 200g, grape seed extract 50g, grape skin extract 200g;

[0055] (2), production: transfer the above-mentioned natural extracts to the container, then add an appropriate amount of auxiliary materials and stir and mix evenly, the obtained mixture is the content, and the mixture is filled in the hard capsule shell to obtain a hard capsule. 1000 hard capsules were prepared, and the net content of each hard capsule was 500 mg.

Embodiment 2

[0056] Embodiment 2: hard capsule

[0057] (1), taking materials: get theaflavin 120g, astaxanthin 160g, grape seed extract 90g, grape skin extract 160g;

[0058] (2), preparation method is the same as embodiment 1, makes 1000 hard capsules altogether, and the content net content of every hard capsule is 500mg.

Embodiment 3

[0059] Embodiment 3: hard capsule

[0060] (1), taking materials: get theaflavin 180g, astaxanthin 120g, grape seed extract 120g, grape skin extract 120g;

[0061] (2), production: production method is the same as embodiment 1, makes 1000 hard capsules altogether, and the content net content of every hard capsule is 500mg.

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Abstract

The invention relates to a natural extract composition having an oxidation resistant effect, a preparation and an application. The natural extract composition comprises the following components in parts by weight of 0.5-3 parts of theaflavin, 0.5-2 parts of astaxanthin, 0.5-2 parts of a grape seed extract and 0.5-2 parts of a grape skin extract. The preparation contains the natural extract composition. The invention further provides the application of the natural extract composition for preparing medicines having the oxidation resistant effect. The theaflavin regulates a bioactivity enzyme system, so that the production of free radicals can be directly or indirectly removed or restrained, and lipid peroxidation can be restrained; the astaxanthin quenches singlet oxygen and eliminate free radicals, so that membrane permeability can be reduced, an oxidizing agent can be limited from permeating into cells, and the defending effect of an endogenous antioxidative enzyme system can be improved; proanthocyanidins can effectively eliminate superoxide anion free radicals and hydroxyl radicals; and resveratrol can remove or restrain the generation of the free radicals, restrain lipid peroxidation and regulate enzymic activity relevant to oxidation resistance.

Description

technical field [0001] The invention relates to a natural extract composition, preparation and application with antioxidant effect, and belongs to the technical field of research and development of health food. Background technique [0002] Oxidation is the increase of free radicals in the process of the body losing electrons; aging is the gradual decline and aging of body functions and organs with age. The aging process can be divided into two parts, one part is related to aging, and the other part is oxidation. For example, the increase of free radicals in the body, the decrease of hormones or the change of chromosomes accelerate aging. The aging process includes the important role of oxidation. The key point is that oxidation is a part of aging, but not the whole of aging. Therefore, anti-aging is more important in comparison with each other. Oxidation is included in the aging process, which is a very important concept. Antioxidant can effectively delay the speed of body...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/10C12P17/16A61K36/87A61P39/06A61K31/353A61K31/122A61K36/82
CPCA23L33/10A23L33/105A61K31/122A61K31/353A61K36/82A61K36/87A61K2236/19A61K2236/35A61K2236/39A61K2236/51A61K2236/55C12P17/162A61K2300/00
Inventor 任雪音刘剑宏浦平南曹后建
Owner JIANGSU DEHE BIOTECH
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