Reagent cartridge for detection of cells

Abstract

An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. A delivery portion ofthe housing defines a delivery path between the reagent volume and the reaction chamber when the housing is coupled to the reaction chamber. The delivery path includes a protrusion such that the delivery path has a discontinuous inner surface. The actuator can be moved to convey a reagent from the reagent container into the reaction chamber via the delivery path.

Description

technical field [0001] Embodiments described herein relate to systems and methods for cell detection using engineered transducing particles. More specifically, embodiments described herein also relate to containers and instruments within which detection of bacteria can be performed with walkaway functionality in an integrated, closed system. Background technique [0002] Detection of bacteria, especially drug-resistant strains, is an important step in diagnosing bacterial infections and limiting the spread of bacterial infections. For example, MRSA is a drug-resistant variant of the common Staphylococcus aureus that is carried by a large portion of the population in the United States. The majority of MRSA infections occur in hospitals and can have a high mortality rate (data from 2010 indicate that approximately 19,000 people die from MRSA infections each year in the United States). Therefore, there is a need for efficient, accurate and rapid identification of bacterial st...

AI Technical Summary

Problems solved by technology

Thus, known systems and methods require skilled personnel and skilled handling of samples, which increases the likelihood of false positives or negatives

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