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Portable multi-sample detection fiber optic biosensor

A biosensor, multi-sample technology, used in instruments, measuring devices, scientific instruments, etc., can solve the problems of large size and weight of instruments, complex optical paths of the system, inconvenient to carry, etc. Portable effect

Inactive Publication Date: 2018-06-15
HUAQIAO UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art, and provide a portable multi-sample detection optical fiber biosensor, which solves the problems of large volume and weight, inconvenient carrying, complex optical path of the system and poor stability in the above-mentioned background technology. question

Method used

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  • Portable multi-sample detection fiber optic biosensor

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Embodiment 1

[0027] Please check figure 1 , the present embodiment is a simultaneous rapid detection of mercury ions (Hg 2+ ) and silver ions (Ag + ) fiber optic sensor.

[0028] The light source module 1 uses a semiconductor laser with a center wavelength of 405nm and a fiber output power of 20mW. The output pigtail is a multimode fiber with a core and cladding diameters of 105μm and 125μm, respectively.

[0029] The optical splitting module 2 adopts a 2×2 optical fiber coupler with a splitting ratio of 50:50 prepared by the fusion tapered method. The optical fiber used is a 105 μm / 125 μm multimode optical fiber. The two ports on the left are respectively connected to the light source module 1 and the optical filter module 4. , the two ports on the right are connected to two fiber optic probes 3 .

[0030] Optical fiber probe 3 is to prepare a 105μm / 125μm multimode optical fiber into a cone-column combination structure by hydrofluoric acid chemical etching, and then bioactivate the ami...

Embodiment 2

[0036] The difference between Embodiment 2 and Embodiment 1 is that the light source module 1 of this embodiment includes a combined module with a broadband light source, a filter unit and a spatial light-fiber coupling device; the broadband light source includes an LED flashlight of a mobile device 5, White light laser or other broadband light sources with blue-violet wavelengths; the filter unit includes one of dichroic mirrors or filters for separating blue-violet light from broadband light sources as excitation light for quantum dots, the The spatial light-fiber coupling device is used to couple the light passing through the filter unit to the light splitting module 2 .

[0037] A portable multi-sample detection optical fiber biosensor according to the present invention also includes a housing, which can be used to package the light source module, spectroscopic module, filter module, and / or optical fiber probe, and / or mobile device , the housing is provided with an optical...

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Abstract

The invention discloses a portable multi-sample detection fiber optic biosensor. The fiber optic biosensor comprises a light source module, a light splitting module, a fiber optic probe, a filter module and a mobile device. A laser signal is transmitted to the fiber optic probe through the light splitting module and excites the quantum dot of the probe to produce a fluorescence signal, then the signal is reversely transmitted to the filter module, then the signal light is detected through a camera of the mobile device and the detection of different samples is realized through separation basedon an algorithm. The imaging detection and image processing are used in the fiber optic biosensor. The fiber optic biosensor has a compact structure, has a small size, is portable, greatly improves the utilization efficiency of laser and fluorescence and can be widely used in the fields of food safety, biomedicine, environmental monitoring and military.

Description

technical field [0001] The invention relates to a portable multi-sample detection optical fiber biosensor. Background technique [0002] Optical fiber biosensor is a kind of sensor that uses optical fiber as the carrier to conduct and collect optical signals to realize biological detection. It combines the advantages of optical fiber sensor with strong anti-electromagnetic With the advantages of high specificity and high sensitivity, it has broad application prospects in fields such as biomedicine, environmental monitoring, clinical diagnosis, and food safety. [0003] At present, in order to realize multi-sample detection, the signal detection modules of existing optical fiber biosensors are mainly based on photodetection devices such as photodiodes, photomultiplier tubes, and avalanche photodiodes. Simultaneous detection, resulting in large volume and weight of the instrument, inconvenient to carry, and the optical path of the system is complicated and the stability is po...

Claims

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Application Information

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IPC IPC(8): G01N21/64G01N21/01
CPCG01N21/01G01N21/6428
Inventor 刘婷王文琪刘志群易定容
Owner HUAQIAO UNIVERSITY
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