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Composition used for treating arthritis, and preparation method thereof

A complex, arthritic technique applied in orthopedics to address issues such as misfit

Inactive Publication Date: 2018-07-24
和平一号生物科技(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its disadvantages are: PRP technology needs to extract the patient's own blood for separation and injection, so patients with blood diseases are not suitable for PRP technology treatment, such as thrombocytopenia, aplastic anemia, leukemia, etc.

Method used

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  • Composition used for treating arthritis, and preparation method thereof
  • Composition used for treating arthritis, and preparation method thereof
  • Composition used for treating arthritis, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Embodiment 1: Preparation of the compound for treating arthritis

[0072] 1. Preparation of universal plasma

[0073] The general-purpose plasma provided in this example is liquid general-purpose fresh frozen plasma:

[0074] The volume parts of plasma of various blood types are:

[0075] Type A plasma: 5 parts by volume; Type B plasma: 2 parts by volume; Type O plasma: 2 parts by volume; Type AB plasma: 1 part by volume;

[0076] The preparation method is:

[0077] The collected qualified plasma was quickly frozen at -30°C, and the four blood types of A, B, O, and AB were mixed according to the above volume ratio, and after the virus was inactivated, an appropriate amount of protective agents sucrose and glutathione were added. Concentrated by filtration and sterilized.

[0078] 2. Preparation of multifunctional human plasma

[0079] Take 10ml of general-purpose fresh frozen plasma prepared in step 1, and keep the temperature of general-purpose fresh frozen plasma...

Embodiment 2

[0089] Embodiment 2: Preparation of the compound for treating arthritis

[0090] 1. General-purpose plasma preparation

[0091] The general-purpose plasma provided in this example is liquid general-purpose fresh frozen plasma:

[0092] The volume parts of plasma of various blood types are:

[0093] Type A plasma: 5 parts by volume; Type B plasma: 3 parts by volume; Type O plasma: 1 part by volume; Type AB plasma: 1 part by volume;

[0094] The preparation method is:

[0095] The collected qualified plasma was quickly frozen at -30°C, and the four blood types plasma of A, B, O and AB were mixed according to the above volume ratio, and after the virus was inactivated, an appropriate amount of protective agents mannitol and glucose were added, and ultrafiltration was concentrated , Sterilized.

[0096] 2. Preparation of multifunctional human plasma

[0097] Take 10ml of general-purpose fresh frozen plasma prepared in step 1, and keep the temperature of general-purpose fresh ...

Embodiment 3

[0105] Example 3: Preparation of compound for treating arthritis

[0106] 1. General-purpose plasma preparation

[0107] The general-purpose plasma provided in this example is liquid general-purpose fresh frozen plasma:

[0108] The volume parts of plasma of various blood types are:

[0109] Type A plasma: 6 parts by volume; Type B plasma: 3 parts by volume; Type O plasma: 0.5 parts by volume; Type AB plasma: 0.5 parts by volume;

[0110] The preparation method is:

[0111] The collected qualified plasma was quickly frozen at -30°C, and the four blood types of A, B, O and AB were mixed according to the above volume ratio, and after the virus was inactivated, an appropriate amount of protective agent calcium chloride was added, and ultrafiltration was concentrated. , Sterilized.

[0112] 2. Preparation of multifunctional human plasma

[0113] Take 10ml of general-purpose fresh frozen plasma prepared in step 1, and keep the temperature of general-purpose fresh frozen plasma...

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PUM

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Abstract

The invention relates to a composition used for treating arthritis, and a preparation method thereof, and belongs to the technical field of medical science, skin repairing, and plastic surgery. A blood plasma mixture comprises universal blood plasma and a blood component additive; the universal blood plasma is universal fresh frozen blood plasma or universal frozen dried blood plasma; the universal fresh frozen blood plasma or universal frozen dried blood plasma are prepared from, by volume, 5 to 10 parts of A type blood plasma, 2 to 7 parts of B type blood plasma, 0.5 to 3 parts of O type blood plasma, 0.5 to 3 parts of AB type blood plasma via mixing. The multifunctional human blood plasma can be used for patients with thrombocytopenia, leukemia, and other arthritis. According to an application method, matching is carried out via inputting blood test results and synovial fluid test results into a computer, in vitro blending is carried out, and injection into human body articular cavities is carried out.

Description

technical field [0001] The invention relates to a compound for treating arthritis and a preparation method thereof, and belongs to the technical fields of orthopedics such as medicine, joint pain treatment and joint repair. Background technique [0002] Osteoarthritis (OA) is a common, multiple, degenerative disease, and its typical pathological features are destruction of articular cartilage, changes in subchondral bone structure, and occurrence of osteophytes. At present, among the elderly over 60 years old in my country, 55% of people suffer from osteoarthritis, and the prevalence rate increases year by year with age. As China gradually enters an aging society and the average life expectancy of Chinese people increases, about 120 million people are suffering from osteoarthritis. Due to poor local blood supply and bone marrow stem cell lesions, patients with osteoarthritis usually have limited self-regeneration and repair capabilities. Without therapeutic intervention, jo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/19A61K45/06A61P19/02A61P29/00A61K35/16A61K31/728A61K31/7008A61K31/737A61K31/4409A61K31/7036A61K31/496A61K31/616A61K31/405A61K31/573A61K31/4706
CPCA61K35/16A61K31/405A61K31/4409A61K31/4706A61K31/496A61K31/573A61K31/616A61K31/7008A61K31/7036A61K31/728A61K31/737A61K35/19A61K45/06A61K2300/00
Inventor 杜祖英
Owner 和平一号生物科技(北京)有限公司
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