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Pharmaceutical composition for treating heart failure and preparation method thereof

A heart failure and composition technology, which is applied in the field of pharmaceutical compositions for the treatment of heart failure and their preparation, can solve problems such as unsatisfactory curative effects, and achieve the effects of no toxic side effects, good safety, and improved survival rate

Active Publication Date: 2018-07-24
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chen Cui et al., "Observation on Clinical Efficacy of Modified Siwu Decoction in Treating 52 Cases of Acute Heart Failure", Practical Integrative Medicine of Traditional Chinese and Western Medicine, 2015, 15(5), disclosed that modified Siwu Decoction has a certain effect on the treatment of acute heart failure, but The curative effect is still not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0029] Weigh 15g of Bupleurum bupleuri, 20g of oysters, 20g of angelica, 50g of wild jujube seed, 30g of Radix Acanthopanax, 20g of raw sun-dried ginseng, 10g of cinnamon, and 15g of Polygonatum odoratum.

[0030] Preparation:

[0031] First put the raw oysters into the casserole, add 2500ml of water, and soak for half an hour. After boiling for 0.5 hours on high fire, add bupleurum, angelica, wild jujube seed, red hair five plus skin, raw sun-dried ginseng, cinnamon, and polygonatum, and continue to cook until 200ml is left, pour the cooked liquid into the in a clean container. Add 1500ml of water to the above-mentioned remaining medicinal residues, boil with high fire for 0.5 hour, then boil with slow fire (low fire) until 200ml is left, and take it twice before and after.

Embodiment 2

[0032] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0033] Weigh 12g of Bupleurum bupleuri, 16g of oysters, 16g of angelica, 40g of wild jujube seed, 24g of Radix Acanthopanax, 24g of raw sun-dried ginseng, 12g of cinnamon, and 18g of Polygonatum odoratum.

[0034] Preparation method: with the preparation method of embodiment 1.

Embodiment 3

[0035] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0036] Weigh 18g of Bupleurum bupleuri, 24g of oysters, 24g of angelica, 60g of wild jujube seed, 36g of Radix Acanthopanax, 16g of raw sun-dried ginseng, 8g of cinnamon, and 12g of Polygonatum odoratum.

[0037] Preparation method: with the preparation method of embodiment 1.

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Abstract

The invention provides a pharmaceutical composition for treating heart failure. The pharmaceutical composition is prepared from 12-18 parts by weight of radix bupleuri, 16-24 parts by weight of oyster, 16-24 parts by weight of radix angelicae sinensis, 40-60 parts by weight of spina date seed, 24-36 parts by weight of cortex acanthopanacis giraldii, 16-24 parts by weight of raw sun ginseng, 8-12 parts by weight of cassia bark and 12-18 parts by weight of radix polygonati officinalis. The invention also provides a preparation method and use of the pharmaceutical composition. The pharmaceuticalcomposition has reasonable compatibility and good therapeutic effects on various heart failures, has good safety and provides a novel clinical drug.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a medicine composition for treating heart failure and a preparation method thereof. Background technique [0002] Heart failure (heart failure) referred to as heart failure refers to the failure of the venous blood to fully discharge the heart due to the dysfunction of the systolic function and / or diastolic function of the heart, resulting in blood stasis in the venous system and insufficient blood perfusion in the arterial system, resulting in Cardiac circulatory disorder syndrome, which is characterized by pulmonary congestion and vena cava congestion. Heart failure is not an independent disease, but the end stage of the development of heart disease. Almost all cardiovascular diseases, such as myocardial infarction, cardiomyopathy, hemodynamic overload, inflammation, etc., can cause changes in myocardial structure and function, and finally lead to hypoventricular pumping a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P9/04A61K35/618
CPCA61K35/618A61K36/232A61K36/233A61K36/254A61K36/258A61K36/54A61K36/725A61K36/8969A61K2300/00
Inventor 高培阳张松张传涛张雪梅王春霞郭留学
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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