The invention provides a pharmaceutical composition for treatment of arthralgia, dermatosis and gynecopathy. The pharmaceutical composition is a preparation prepared from the following bulk drugs by weight: 60-130 parts of Juniperus formosana, 60-130 parts of Rhododendron anthopogonoides, 60-130 parts of Artemisia sieversiana, 60-130 parts of ephedra, 60-130 parts of Myricaria bracteata, 20-40 parts of polygonatum rhizome, 20-40 parts of radix asparagi, 20-40 parts of Chinese angelica, 20-50 parts of radix Mirabilis himalaicae, 20-50 parts of tribulus terrestris, 30-70 parts of amber, 30-70 parts of cassia seed, 30-70 parts of Hibiscus abelmoschus seeds, 20-50 parts of safflower, and 30-70 parts of Butea monosperma. The pharmaceutical composition provided by the invention has a precise andappropriate formula, has the efficacy of sweating, inflammation diminishing, pain relieving, alleviating yellow water, promoting blood circulation and dredging collaterals, can be used for arthralgia, i.e. rheumatic arthritis, rheumatoid arthritis, gout, hemiplegia, dermatosis, female postpartum diseases and the like, and has good clinical application prospect.