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Application of kalimeris indica or kalimeris indica extract to preparation of drugs for treating non-infectious inflammation and drugs

A non-infectious, extractive technology, applied in the field of medicine, can solve the problems of low patient tolerance, long treatment cycle and poor curative effect of non-infectious enteritis, so as to relieve physical pain, eliminate psychological panic, and improve tolerance Effect

Active Publication Date: 2018-08-03
CHONGQING HONOROAD ANIMAL HEALTH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The first purpose of the present invention is to provide the application of Malan or Malan extract in the preparation of medicines for the treatment of non-infectious inflammation, thereby solving the problems of long treatment cycle, poor curative effect and low patient tolerance of non-infectious enteritis at the present stage

Method used

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preparation example Construction

[0030] A more preferred method is the heating reflux extraction method. More specifically, the preparation method of the Malan extract comprises: heating the Malan extract to reflux at 75-90° C. for 2-3 hours with 45-55 wt % ethanol solution, and filtering the obtained The dregs are heated and refluxed at 75-90° C. with 45-55 wt % ethanol solution for 1-2 hours, and the filtrates obtained from two extractions are combined and concentrated under reduced pressure to obtain Malan extract.

[0031]More preferably, after the Malan extract is extracted by solvent extraction, the Malan extract is obtained; subsequently, the Malan extract is extracted with a low-polarity solvent, and the obtained large polar part is the Malan extract. The specific process is: remove the organic solvent in the obtained Malan extract, keep the water phase, then add a certain volume of low polarity solvent to the water phase for extraction, extract 2 to 3 times, and extract the obtained The water phase w...

Embodiment 1

[0036] The present embodiment provides a kind of medicine for treating radiation enteritis, and this medicine is oral liquid, and its preparation method is:

[0037] Fresh whole Malan herb is 1kg, quickly wash the roots to carry the sediment, and cut into sections. Add about 5L of water to a glass container and decoct, keep boiling slightly for 30 minutes after boiling, pour out the liquid medicine, add an appropriate amount of preservatives, subpackage, 250mL / bottle, and then make an oral liquid with a content of about 200g fresh medicinal materials / L. One bottle at a time, swallow slowly, and finish within 1 hour. Take 3 times a day.

Embodiment 2

[0039] The present embodiment provides a kind of medicine for treating radiation enteritis, and this medicine is granule, and its preparation method is:

[0040] Dry 10kg of Malan whole herb, crush it into coarse powder, add 80L of 50% ethanol to heat and extract in a stainless steel traditional Chinese medicine extraction tank, reflux for 2 hours, and obtain the extract after filtering. The residue was extracted with 50 L of 50% ethanol under reflux for 1 hour, and the extract was obtained after filtration. The extracts obtained twice were combined, and the ethanol was recovered under reduced pressure until there was no alcohol smell, and about 55 L of concentrated solution was obtained. The concentrated solution was extracted twice with petroleum ether, each time the volume of the concentrated solution was 1 / 2. Separate the aqueous phase and concentrate it to 10L.

[0041] Take 5kg of glucose and 4kg of sucrose and mix them as an absorbent; use a fluidized bed granulator, ...

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Abstract

The invention provides application of kalimeris indica or a kalimeris indica extract in preparation of drugs for treating non-infectious inflammation. Through the kalimeris indica, the problems of treatment of the non-infectious enteritis at the present stage that the cycle is long, the treatment effect is poor, and the patient tolerance is low can be effectively solved. The invention further provides the drugs for treating the non-infectious inflammation. By the drugs, the treatment cycle of the non-infectious inflammation can be greatly shortened, and inflammation wound surfaces of patientscan be rapidly restored.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application and medicine of Malan or Malan extract in the preparation of medicine for treating non-infectious inflammation. Background technique [0002] Inflammation is a very common and important basic pathological process, and it is a defense response of the body to stimuli. Usually, the infectious diseases caused by microbial infections such as bacteria are mainly treated with antibiotics, and the curative effect is remarkable. However, for some non-infectious inflammations, that is, physical inflammations, the course of the disease is long and the damage to the patient is great. There is no good treatment plan for this type of infection. Let's take radiation enteritis as an example to illustrate. [0003] With the advancement of radiotherapy technology, radiotherapy has become an important method for the comprehensive treatment of many malignant tumors. More than 300,000 peopl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P1/00A61P29/00
CPCA61K36/28A61P1/00A61P29/00
Inventor 赵德邓君任丽任敏王国勤蒋佳璇杨志灵
Owner CHONGQING HONOROAD ANIMAL HEALTH
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