A traditional Chinese medicine for treating restless legs syndrome and its preparation method

A syndrome and uneasy technology, applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of large side effects of western medicine and achieve high safety effects

Active Publication Date: 2021-06-04
NANJING HOSPITAL OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The invention provides a traditional Chinese medicine for treating restless legs syndrome with remarkable curative effect and little side effects and a preparation method thereof, which solves the problems of large side effects of existing western medicines and the like

Method used

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  • A traditional Chinese medicine for treating restless legs syndrome and its preparation method
  • A traditional Chinese medicine for treating restless legs syndrome and its preparation method
  • A traditional Chinese medicine for treating restless legs syndrome and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1: 8 copies, 8 parts of angelica, 40 white peony, 12 copies of Chuanxiong, 4 parts of the ground, 25 copies of the squid, 25 servants, 12 copies of licorice, the white peony fried white peony , Licorice is a honey licorice, and the preparation method includes the following steps:

[0030] a. Take Chuanxiong, when retreating volatile oil, the amount of water is 10 times the weight of the weight of the drug, soak for 1 hour, water vapor distillation for 3 hours; volatile oil plus 4-8 times weight β-cyclodextrin, The β-cyclodextrin volatilizing the oil adherate was prepared by a saturated aqueous solution method. When the coating temperature was 30 ° C, the stirring velocity was: 120 r / min, the incubation was 0.5 hours, and the incubation was mixed after vacuum drying, and the aqueous solution was distilled after vacuum. Also collecting;

[0031] b. Take the white peony, whole scorpion, spathol vine, ground mites, extract through ethanol reflux, each time the amount ...

Embodiment 2

[0034] Example 2: 12 copies, 4 parts of Angelica, 60 white peony, 8 copies of Chuanxiong, 8 parts of the gesta, 35 parts of the squad, 35 servants, 8 serums, the white peony , Licorice is a honey licorice, and the preparation method includes the following steps:

[0035] a. Take Chuanxiong, when retreating volatile oil, the amount of water is 10 times the weight of the weight of the drug, soak for 1 hour, water vapor distillation for 3 hours; volatile oil plus 4-8 times weight β-cyclodextrin, The β-cyclodextrin volatilizing the oil adherate was prepared by a saturated aqueous solution method. When the coating temperature was 30 ° C, the stirring velocity was: 120 r / min, the incubation was 0.5 hours, and the incubation was mixed after vacuum drying, and the aqueous solution was distilled after vacuum. Also collecting;

[0036] b. Take the white peony, whole scorpion, spathol vine, ground mites, extract through ethanol reflux, each time the amount of ethanol is 12 times the total ...

Embodiment 3

[0039] Example 3: 10 parts of life, 6 parts of angelica, 50 white peony, 10 copies of Chuanxiong, 4 parts of the midst, 30 pieces of sputum, 10 grasses, licorice, the white peony fried white peony , Licorice is a honey licorice, and the preparation method includes the following steps:

[0040] a. Take Chuanxiong, when retreating volatile oil, the amount of water is 10 times the weight of the weight of the drug, soak for 1 hour, water vapor distillation for 3 hours; volatile oil plus 4-8 times weight β-cyclodextrin, The β-cyclodextrin volatilizing the oil adherate was prepared by a saturated aqueous solution method. When the coating temperature was 30 ° C, the stirring velocity was: 120 r / min, the incubation was 0.5 hours, and the incubation was mixed after vacuum drying, and the aqueous solution was distilled after vacuum. Also collecting;

[0041] b. Take the white peony, whole scorpion, spathol vine, ground mites, extract through ethanol reflux, each time the amount of ethanol...

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Abstract

The invention discloses a traditional Chinese medicine for treating restless legs syndrome and a preparation method thereof. ‑12 parts, 4‑8 parts of ground soft-shelled turtle, 3‑7 parts of scorpion, 25‑35 parts of Caulis Spatholobus, 8‑12 parts of licorice; the volatile oils of angelica and Chuanxiong are extracted and clathrated by β‑cyclodextrin Radix Paeoniae Alba, Scorpio, Spatholobus Spatholobus, and Ground Beetle are refluxed with ethanol, and the raw land, licorice, and medicinal residues are decocted in water to prepare a preparation, which has the effect of treating restless legs syndrome, especially for yin deficiency and blood stasis type Restless legs syndrome, no obvious toxic side effects were found in the research, and the safety is high. This product can be made into a pharmaceutical oral liquid, which can be widely used.

Description

Technical field [0001] The present invention relates to the field of traditional Chinese medicine, and more particularly to traditional Chinese medicine and preparation methods and applications thereof in the treatment of uneasing leg syndrome. Background technique [0002] RESTLESS LEGS SYNDROME, RLS is a common central sensory distortion of the legs. Patients sleep at night or quiet, there is a bilateral calf, such as insects, tingling, swelling, numbness, and strong activities, beat, acting legs or low bed walking Energy relieve symptoms. RLS synthesis often with insomnia, sleep fragmentation, sleepiness and anxiety, depression symptoms, seriously affecting life, and is easy to misdiagnose. The survey of several countries in Europe and the United States showed that the overall incidence of RLS syndrome was 5% -15%, and the incidence of women and men was about 2: 1; the incidence rate increased with age, and the number of births increased. The 2012 report showed that RLS was 7....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K47/69A61P25/00A61K35/646A61K35/64
CPCA61K35/646A61K36/232A61K36/236A61K36/484A61K36/486A61K36/65A61K36/71A61K36/804A61K2236/331A61K2236/39A61K2236/55A61K35/63A61K47/6951A61P25/00A61K2300/00
Inventor 冉颖卓
Owner NANJING HOSPITAL OF T C M
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