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Post-ahypnia headache medicine and preparation method thereof

A technology of post-headache and rehmannia, applied in the field of post-insomnia headache medicine and its preparation, can solve problems such as dizziness, digestive disorders, and unsatisfactory treatment effects on post-insomnia headache, and achieve the effects of no toxic side effects, significant curative effect, and reduced loss

Inactive Publication Date: 2018-10-19
HEILONGJIANG ACAD OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the unsatisfactory drug treatment effect of existing methods for treating headache after insomnia, especially the technical problem of side effects of drowsiness, dizziness and digestive disorders caused by long-term use of western medicine, and provides a kind of headache medicine after insomnia and its preparation method

Method used

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  • Post-ahypnia headache medicine and preparation method thereof
  • Post-ahypnia headache medicine and preparation method thereof
  • Post-ahypnia headache medicine and preparation method thereof

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specific Embodiment approach 1

[0059] Specific embodiment one: a kind of headache medicine after insomnia of this embodiment comprises Rehmannia glutinosa 15g-25g, angelica 15g-25g, jujube seed 35g-45g, cypress kernel 10g-20g, Polygala 10g-20g, Shichangpu 10g-20g, Ligusticum chuanxiong 10g-20g, Radix Paeoniae Alba 25g-35g.

specific Embodiment approach 2

[0060] Embodiment 2: This embodiment differs from Embodiment 1 in that a headache medicine for insomnia includes 20g rehmannia root, 20g angelica, 40g jujube seed, 15g cypress kernel, 15g polygala, 15g Shichangpu, 15g chuanxiong, and white peony 30g. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0061] Specific embodiment three: the preparation method of a kind of post-insomnia headache medicine described in specific embodiment one is as follows:

[0062] 1. Weigh rehmannia 15g-25g, angelica 15g-25g, jujube seed 35g-45g, cypress kernel 10g-20g, polygala 10g-20g, calamus shichangpu 10g-20g, chuanxiong 10g-20g, white peony root 25g-35g ;

[0063]2. Then mix Chuanxiong, Suanzaoren, Angelica, Shichangpu, and Baiziren with water, and the amount of water added is 8 times the total mass of Chuanxiong, Suanzaoren, Angelica, Shichangpu, and Baiziren, soak for 1 hour, and distill and extract for 6 hours , to obtain volatile oil, mix the volatile oil and cyclodextrin according to the mass ratio of 1:8, under the condition of inclusion temperature of 60 ℃, inclusion complex for 1 hour, obtain beta-cyclodextrin inclusion compound;

[0064] 3. Export the remaining aqueous solution after distillation in step 2, mix the distilled medicine dregs with rehmannia root, Radix Paeoniae Al...

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Abstract

The invention discloses an ahypnia headache medicine and a preparation method of the medicine, and relates to a medicine for treating an ahypnia headache and a preparation method of the medicine. Themedicine solves the technical problems that the existing method for treating the post-ahypnia headache has a non-ideal medication effect, and especially, a western medicine has side effects of hypersomnia, dizziness and digestive disorders after long-term administration. The medicine comprises radix rehmanniae recen, Chinese angelica, spina date seeds, semen platycladi, polygala roots, rhizoma acori graminei, ligusticum wallichii and radix paeoniae alba. The preparation method comprises the steps of mixing the ligusticum wallichii, the spina date seeds, the Chinese angelica, the rhizoma acorigraminei, the semen platycladi and water for distillation and extraction, preparing a beta cyclodextrin inclusion compound, mixing and decocting decoction dreg after distillation with the radix rehmanniae recen, the radix paeoniae alba and the polygala roots, mixing a residual aqueous solution after the distillation with filtrate, performing pressure reduction concentration, standing, cooling to aroom temperature, adding ethanol, performing uniform mixing, refrigeration, filtration, pressure reduction, drying and grinding, and adding the beta cyclodextrin inclusion compound. The medicine hasan effective rate of 94.30% for treating the post-ahypnia headache, the hypersomnia, the dizziness and the digestive disorders do not occur, and a recurrence rate is less than 26%.

Description

technical field [0001] The invention relates to a post-insomnia headache medicine and a preparation method thereof. Background technique [0002] Medications for headache after insomnia can partially or completely relieve the pain. Common medicines for headache after insomnia include aspirin, pain-reducing tablets, paracetamol, phenylbutazone, rofecoxib, etc.; After taking insomnia headache tablets, drug dependence will occur. [0003] Chinese medicine, as the quintessence of the country and the main component of traditional medicine, has been paid more and more attention to, and foreign countries have also paid more and more attention to the research of Chinese patent medicine. Since traditional Chinese medicine decoction pieces basically come from natural animals and plants, it is generally believed that the toxic and side effects of Chinese patent medicines are relatively low. Research on Chinese patent medicines for headache after insomnia can reduce patients' dependen...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61K47/69A61P25/00A61P25/20
CPCA61K36/14A61K36/232A61K36/236A61K36/65A61K36/69A61K36/71A61K36/725A61K36/804A61K36/888A61K47/6951A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P25/00A61P25/20A61K2300/00
Inventor 王顺
Owner HEILONGJIANG ACAD OF TCM
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