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Pharmaceutical composition for treating psoriasis and application method thereof

A pharmaceutical composition and technology for psoriasis, applied in the field of medicine, can solve problems such as limited therapeutic effect, achieve excellent therapeutic effect, good therapeutic effect, and maintain activity

Pending Publication Date: 2018-10-23
毛莉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] After actual verification, the therapeutic effect of these prescriptions is very limited, and often can only achieve a short-term control effect, as short as 2 weeks, and as long as half a year, it will relapse again

Method used

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  • Pharmaceutical composition for treating psoriasis and application method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A pharmaceutical composition for treating psoriasis, comprising Pokeweed extract, component A and component B;

[0045] The preparation method of the pokeweed extract is as follows: after the pokeweed is harvested, the leaves are removed, dried and crushed in an oven at 60°C, and then put into the extraction kettle, and the refrigeration device, the extraction kettle and the heating device are normal After work, turn on the compression pump to pressurize to the required pressure, adjust the CO 2 flow rate, for supercritical CO 2 Extraction, fixed separation pressure 4MPa during extraction, extraction pressure 30MPa, extraction temperature 50°C, CO 2 The flow rate is 18L / h, and the extraction time is 4.5h. After extraction, the liquid in the separation tank is collected, water and dichloromethane are added to extract and separated, and the dichloromethane phase is concentrated under reduced pressure and dried to obtain the pokeweed extract ;

[0046] The A component i...

Embodiment 2

[0054] A pharmaceutical composition for treating psoriasis, comprising Pokeweed extract, component A and component B;

[0055] The preparation method of the pokeweed extract is as follows: after the pokeweed is harvested, the leaves are removed, dried and crushed in an oven at 60°C, and then put into the extraction kettle, and the refrigeration device, the extraction kettle and the heating device are normal After work, turn on the compression pump to pressurize to the required pressure, adjust the CO 2 flow rate, for supercritical CO 2 Extraction, fixed separation pressure 4MPa during extraction, extraction pressure 30MPa, extraction temperature 50°C, CO 2 The flow rate is 15 L / h, and the extraction time is 4 hours. After the extraction, the liquid in the separation tank is collected, water and dichloromethane are added for extraction, and the liquid is separated. The dichloromethane phase is concentrated under reduced pressure and then dried to obtain the pokeweed extract; ...

Embodiment 3

[0064] A pharmaceutical composition for treating psoriasis, comprising Pokeweed extract, component A and component B;

[0065] The preparation method of the pokeweed extract is as follows: after the pokeweed is harvested, the leaves are removed, dried and crushed in an oven at 60°C, and then put into the extraction kettle, and the refrigeration device, the extraction kettle and the heating device are normal After work, turn on the compression pump to pressurize to the required pressure, adjust the CO 2 flow rate, for supercritical CO 2 Extraction, fixed separation pressure 4MPa during extraction, extraction pressure 30MPa, extraction temperature 50°C, CO 2 The flow rate is 15 L / h, and the extraction time is 3 hours. After the extraction, the liquid in the separation tank is collected, water and dichloromethane are added for extraction, and the liquid is separated. The dichloromethane phase is concentrated under reduced pressure and then dried to obtain the pokeweed extract; ...

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Abstract

The invention provides a pharmaceutical composition for treating psoriasis and an application method thereof and relates to the technical field of medicine. The pharmaceutical composition comprises Phytolacca Americana L. extract, a component A and a component B, wherein the component A comprises, by weight, 30-40 parts of fructus cnidii, 30-40 parts of purslane, 10-18 parts of periostracum cicada, 6-12 parts of radix sophorae flavescentis, 6-12 parts of poria cocos, 4-10 parts of panax notoginseng, 4-10 parts of angelica sinensis, 4-10 parts of radix lithospermi, 1-5 parts of radix rubiae, 1-5 parts of hedyotis diffusa and 1-5 parts of radix isatidis; the component B comprises, by weight, 5-10 parts of honey, 10-20 parts of salicylic acid, 1-2 parts of betaine, 0.1-1 part of butanediol, 8-12 parts of polyglycerol, 0.1-1 part of 1,2-pentanediol, 0.1-1 part of hydrogenated castor oil, 0.1-0.5 part of triethanolamine, 0.1-0.5 part of Carbomer and 40-50 parts of water. The pharmaceuticalcomposition can cure psoriasis vulgaris and psoriasis pustulose.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a pharmaceutical composition for treating psoriasis and an application method thereof. Background technique [0002] Psoriasis, commonly known as psoriasis, is a chronic multiple skin disease that often has a family history and a genetic predisposition. Its characteristic lesions are red papules or plaques covered with multiple layers of silvery white scales. The morphology of its skin lesions varies greatly, and can be manifested as maculopapular rash, annular erythema, erythroderma, pustules, etc., accompanied by itching, which seriously affects people's quality of life. Both men and women, old and young, can suffer from it, and it is more common in young adults, with slightly more men than women. Among the predisposing factors of psoriasis, in addition to family genetic factors, bacterial infection is also a factor that cannot be ignored. In addition, in recent years, stud...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K36/748A61K36/80A61P17/06A61K35/64
CPCA61K47/46A61P17/06A61K9/0014A61K9/06A61K35/63A61K36/076A61K36/11A61K36/185A61K36/19A61K36/195A61K36/232A61K36/234A61K36/258A61K36/28A61K36/30A61K36/315A61K36/34A61K36/489A61K36/74A61K36/748A61K36/80A61K2300/00
Inventor 章立兰
Owner 毛莉
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