Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of sterilized compound magnesium sulfate wet compress composition and its preparation method and application

A technology of magnesium sulfate and composition, applied in the field of medicine, can solve the problems of increasing energy input in medical care, skin friction, irritation of patients, and difficulty in controlling the degree of dryness and wetness, so as to inhibit the function of phagocytes and the synthesis and release of inflammatory mediators. , the effect of relieving vasospasm and facilitating patients and medical staff

Active Publication Date: 2021-04-30
NINGBO NO 2 HOSPITAL
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Wet compress tablets have the advantages of local direct administration, rapid onset of effect, sufficient drug effect, and safe medication. However, in the process of clinical application, wet compresses need repeated operations. The degree of dryness and wetness is not easy to control, and it is easy to touch the clothes and mattresses, which will easily cause the sheets to be soaked, and because the water evaporates quickly, it is easy to precipitate crystals, which makes commonly used medical dressings such as gauze dry and change. Hard, detached from the contact surface, not conducive to drug absorption, short action time, friction, irritation to the patient's skin, causing discomfort and other factors, which greatly increased the energy input in medical care

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of sterilized compound magnesium sulfate wet compress composition and its preparation method and application
  • A kind of sterilized compound magnesium sulfate wet compress composition and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: the preparation of compound magnesium sulfate wet compress composition

[0036] Recipe: a compound magnesium sulfate wet compress composition, comprising the following components in parts by weight: 30 g of magnesium sulfate, 0.01 g of dexamethasone, 1 g of glycerol, 1 g of polyoxyethylene hydrogenated castor oil, 0.5 g of potassium sorbate, containing water Lanolin 0.5g, purified water 66.99g.

[0037] Preparation method: a. Slowly add the magnesium sulfate into purified water according to the formula amount, and stir evenly; b. Add dexamethasone, glycerol, polyoxyethylene hydrogenated castor oil, and sorbic acid in sequence according to the formula amount under stirring Potassium, hydrated lanolin, stop when all above-mentioned substances are dissolved, obtain described compound magnesium sulfate wet dressing composition.

Embodiment 2

[0038] Embodiment 2: the preparation of compound magnesium sulfate wet compress composition

[0039] Recipe: a compound magnesium sulfate wet compress composition, comprising the following components in parts by weight: magnesium sulfate 50g, dexamethasone 0.008g, glycerol 3g, polyoxyethylene hydrogenated castor oil 1g, phenoxyethanol 0.2g, water Lanolin 1g, purified water 44.792g.

[0040]Preparation method: a. Slowly add the magnesium sulfate into purified water according to the formula amount, and stir evenly; b. Add dexamethasone, glycerol, polyoxyethylene hydrogenated castor oil, phenoxy base ethanol, hydrated lanolin until the above-mentioned substances are all dissolved and stop to obtain the described compound magnesium sulfate wet compress composition.

Embodiment 3

[0041] Embodiment 3: the preparation of compound magnesium sulfate wet compress composition

[0042] Recipe: a compound magnesium sulfate wet compress composition, comprising the following components in parts by weight: 50g of magnesium sulfate, 0.01g of dexamethasone, 5g of amino acid moisturizer, 2g of polyoxyethylene hydrogenated castor oil, 0.1g of potassium sorbate, containing water Lanolin 1g, purified water 41.89g.

[0043] Preparation method: a. slowly add the magnesium sulfate into purified water according to the formula amount, and stir evenly; b. under stirring state, add dexamethasone, amino acid moisturizing agent, polyoxyethylene hydrogenated castor oil, and sorbic acid in sequence according to the formula amount Potassium, hydrated lanolin, stop when all above-mentioned substances are dissolved, obtain described compound magnesium sulfate wet dressing composition.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention provides a layer -shaped sterilized wet wet applied towel, including: moisturizing layer, drug layer, color change layer, wet compress layer, fixed layer, and the above -mentioned layer structure is arranged in order; wherein the drug layer is the pharmaceutical layer layerContains compound magnesium sulfate wet composition compositions, including the following weight components: 20 to 60 copies of magnesium sulfate, 5 to 15 parts of segemonone, 0.5 to 5 copies of moisturizing agents, 0.1 to 1 part of preservatives, 0.1 surfactants 0.1~ 2 copies, 0.1 to 1 copy of the skin care agent, 45 to 75 copies of pure water.The laminar -like structure provided by the present invention has the effects of moisturizing, anti -inflammatory and swelling, and used to treat local subcutaneous tissue swelling and pain. It has the advantages of convenient, low cost, and cleanliness.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a sterilized compound magnesium sulfate wet compress composition and a preparation method and application thereof. Background technique [0002] Long-term use of irritating drugs such as intravenous chemotherapy drugs or drugs with high input concentration may easily cause drug leakage and extravasation, as well as local venous infection caused by lax aseptic operation during the infusion process or repeated blood vessel punctures, And cause swelling and pain in local subcutaneous tissue, leading to varying degrees of phlebitis, which brings great pain to the patient. The local symptoms are redness, swelling, burning pain, and cord-like red lines appear along the vein. [0003] Currently clinically used to treat swelling and pain of local subcutaneous tissue, the commonly used method is to soak the medical carrier in the drug solution to form a wet compress and apply it to the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K33/06A61K9/70A61P29/00A61P9/14A61P7/10A61K31/573
CPCA61K9/70A61K31/573A61K33/06A61P7/10A61P9/14A61P29/00A61K2300/00
Inventor 余钻标周裴娟邵亚芳吴一曼
Owner NINGBO NO 2 HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products