A method and device for determining coronary artery flow reserve fraction ffr

A technology of coronary blood flow and coronary artery, applied in the field of biomedical engineering, can solve the problems of damaged coronary blood vessels, uncertainty of coronary blood flow, complicated operation, etc.

Active Publication Date: 2021-08-10
杭州晟视科技有限公司
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  • Abstract
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  • Claims
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Problems solved by technology

[0005] The existing invasive method for measuring coronary artery FFR is complex in operation and has the risk of damaging coronary vessels, while the non-invasive method for measuring coronary artery FFR has great uncertainty in estimating coronary artery blood flow, and thus cannot Calculation of accurate coronary FFR values

Method used

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  • A method and device for determining coronary artery flow reserve fraction ffr
  • A method and device for determining coronary artery flow reserve fraction ffr
  • A method and device for determining coronary artery flow reserve fraction ffr

Examples

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no. 1 example

[0073] The first embodiment of the present invention proposes a method for determining coronary artery FFR, such as figure 1 As shown, the method may include:

[0074] Step S101: Obtain the magnetic resonance image and phase information of the coronary artery entrance of the ascending aorta under the state of coronary artery hyperemia.

[0075] In actual implementation, coronary artery FFR can be defined as the ratio of the average blood pressure at the distal end of the coronary artery to the average blood pressure at the entrance of the coronary artery communicating with the aorta under the condition of complete congestion of the coronary artery's myocardial microcirculation vessels. Therefore, it can be The myocardial microcirculation is sufficiently dilated and congested by injecting the patient with a vasodilator (eg, adenosine), and the patient's ascending aortic coronary entry site is imaged using MRI equipment, specifically, in order to obtain the ascending aortic coro...

no. 2 example

[0104] In order to better reflect the purpose of the present invention, further illustrations are made on the basis of the first embodiment of the present invention.

[0105] In the second embodiment of the present invention, as Figure 9 As indicated, methods for determining coronary FFR include:

[0106] Step S901: Obtain the magnetic resonance image and phase information of the coronary artery entrance of the ascending aorta under the state of coronary artery hyperemia.

[0107] Step S902: Construct a three-dimensional geometric model of the coronary artery entrance of the ascending aorta according to the MRI image of the coronary artery entrance of the ascending aorta; obtain the blood flow velocity field information of the coronary artery entrance of the ascending aorta according to the phase information of the coronary artery entrance of the ascending aorta .

[0108] The implementation manner of step S901 to step S902 is the same as the implementation manner of step S10...

no. 3 example

[0131] In order to better reflect the purpose of the present invention, further illustrations are made on the basis of the foregoing embodiments of the present invention.

[0132] In the third embodiment of the present invention, the method for determining coronary artery FFR includes:

[0133] Step A1: Obtain the magnetic resonance image and phase information of the coronary artery entrance of the ascending aorta in the state of coronary artery congestion.

[0134] Step A2: Construct a three-dimensional geometric model of the coronary artery entrance of the ascending aorta according to the MRI image of the coronary artery entrance of the ascending aorta; obtain the blood flow velocity field information of the coronary artery entrance of the ascending aorta according to the phase information of the coronary artery entrance of the ascending aorta .

[0135] The implementation manner of step A1 to step A2 is the same as the implementation manner of step S101 to step S102, and w...

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Abstract

The embodiment of the present invention discloses a method, device and computer storage medium for determining FFR of coronary artery. The MRI images and phase information of the coronary artery entrance of the artery are used to obtain the three-dimensional geometric model of the coronary artery entrance of the ascending aorta and the information of the blood flow velocity field, and then the blood flow of the left and right branch entrances of the coronary artery is obtained; according to the coronary artery in the state of coronary artery congestion Construct a three-dimensional geometric model of the coronary artery based on the CTA image data; calculate and obtain the blood pressure of various places inside the coronary artery according to the three-dimensional geometric model of the coronary artery and the above-mentioned blood flow; obtain the FFR of the coronary artery according to the measured brachial artery blood pressure and the above-mentioned blood pressure ; The method is simple to operate and can obtain accurate coronary blood flow, so as to quickly and accurately calculate the coronary FFR value.

Description

technical field [0001] The present invention relates to biomedical engineering technology, in particular to a method, device and computer storage medium for determining coronary artery blood flow reserve (FFR, Fractional Flow Reserve). Background technique [0002] According to the report of the Ministry of Health, the risk factors of cardiovascular disease in my country continue to increase, and cardiovascular disease has become the main cause of premature death among Chinese residents, and it is also the number one cause of death in the world. or coronary artery disease) is the most common type of cardiovascular disease, which is mainly due to the deposition of cholesterol and fat in the coronary arteries. Coronary arteries cannot supply sufficient blood to myocardial tissue, leading to angina pectoris and even myocardial infarction. Therefore, how to better evaluate coronary artery ischemia has become the focus of attention in the medical field. [0003] Coronary artery co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/026
CPCA61B5/0263
Inventor 魏润杰吴鹏刘星利高琪
Owner 杭州晟视科技有限公司
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