Skin whitening and brightening lotion, preparation method thereof and tyrosinase inhibitor

A technology of tyrosinase and skin-whitening lotion is applied in skin care preparations, pharmaceutical formulations, cosmetic preparations and other directions, can solve problems such as poor effect and poor whitening effect, and achieves excellent inhibitory effect, simple operation, Formulated for mild effect

Active Publication Date: 2019-02-15
GUANGZHOU KENENG COSMETICS RES CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the poor effect of the whitening and freckle-removing preparations of Chinese herbal medicines in the prior art, the whitening effect is relatively poor, etc., the present invention firstly provides a whitening and brightening water

Method used

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  • Skin whitening and brightening lotion, preparation method thereof and tyrosinase inhibitor
  • Skin whitening and brightening lotion, preparation method thereof and tyrosinase inhibitor
  • Skin whitening and brightening lotion, preparation method thereof and tyrosinase inhibitor

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Experimental program
Comparison scheme
Effect test

no. 1 approach

[0035] The first embodiment of the present invention provides a tyrosinase inhibitor, which includes a tyrosinase inhibitor; the tyrosinase inhibitor includes kudzu root extract and resurrection grass extract. The tyrosinase inhibitor of the invention can well inhibit the activity of tyrosinase, and has excellent whitening effect when used in cosmetics, especially when used in whitening and brightening water.

[0036] Pueraria lobata (wild) Ohwi is the dried root of Pueraria lobata (wild) Ohwi or Puerariathomsonil Benth, which is also known as Pueraria lobata (wild) Ohwi. There are 11 species of Pueraria in my country, and except for Pueraria kudzu which is mainly cultivated artificially, the rest are mainly wild. The Chinese Pharmacopoeia (1990 edition) recorded two original plants of the genus Pueraria mirifica and Pueraria pueraria.

[0037] The main components of kudzu root are: starch, cellulose, protein and total flavonoids, and also contain a small amount of fat, pecti...

no. 2 approach

[0045] The second embodiment of the present invention provides a whitening and brightening lotion comprising the tyrosinase inhibitor of the first embodiment. In the present invention, the activity of tyrosinase can be inhibited by adding a suitable content of the tyrosinase inhibitor of the present invention, so that the whitening and brightening water of the present invention has an excellent whitening effect.

[0046] Wherein, based on the total mass of the whitening and brightening water, the added amount of the tyrosinase inhibitor is 0.01-12%, preferably 0.1-10%, for example: 0.5%, 1%, 2%, 3% %, 5%, 6%, 7%, 8%, etc. When the added amount of the tyrosinase inhibitor is between 0.01-12%, the melanin content in the skin after using the whitening and brightening lotion is reduced. When the addition amount of tyrosinase inhibitor is less than 0.01%, the amount of melanin content reduction is little, can not play the effect of whitening; When the addition amount of tyrosinase...

no. 3 approach

[0068] The second embodiment of the present invention also provides a preparation method of the whitening and brightening lotion according to the present invention, including the step of mixing the components of the whitening and brightening lotion.

[0069] Specifically, the preparation method of the whitening and brightening water of the present invention may comprise the following steps:

[0070] 1. Add water, moisturizing agent, thickener, part of skin conditioner, optional chelating agent, optional pH regulator, fragrance and part of preservative raw materials into the mixing pot, stir and heat to 80-85 ℃;

[0071] 2. Cool to 40-50°C, add tyrosinase inhibitor, solubilizer, remaining skin conditioner, sensitizer, optional antioxidant and remaining preservative and stir evenly;

[0072] 3. Cool to 35-40°C, discharge after passing the inspection, and let stand for 12-48 hours;

[0073] 4. After passing the inspection, sub-package, pack, re-inspect, and put the finished pro...

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Abstract

The invention provides a skin whitening and brightening lotion, a preparation method thereof and a tyrosinase inhibitor. The skin whitening and brightening lotion comprises the tyrosinase inhibitor; the tyrosinase inhibitor comprises, in terms of the total mass of the tyrosinase inhibitor, 0.5%-75% of a kudzuvine root extract and 25%-99.5% of an anastatica extract. The skin whitening and brightening lotion adopts a mild formula, can effectively inhibit activity of tyrosinase and has a skin whitening function. Further, the tyrosinase inhibitor has an excellent inhibiting function on activity oftyrosinase.

Description

technical field [0001] The invention relates to a whitening and brightening water, a preparation method thereof and a tyrosinase inhibitor, belonging to the field of cosmetics. Background technique [0002] Facial pigmentation is a skin concern of great concern. Chloasma, freckles, and melanin deposits affect the appearance and cause troubles to people. Whitening additives can reduce dark deposits or reduce skin tone, and Chinese women are increasingly pursuing fair skin, making the demand for whitening and brightening water continue to rise. [0003] Existing whitening additives in the prior art are mostly organic compounds. These substances have stimulating effect on the skin, have relatively large side effects, increase the harm to the human body, and reduce the safety factor; in addition, a single plant extract is also used as a whitening additive. , but the plant extract has a single whitening component and a relatively simple mechanism of action, and the whitening ef...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9741A61K8/9711A61K8/67A61K8/64A61K8/68A61K8/9722A61K8/65A61K8/49A61K8/99A61K8/9794A61K8/60A61K8/34A61K8/63A61K8/42A61K8/86A61K8/73A61K8/92A61Q19/02A61Q19/00
CPCA61Q19/00A61Q19/02A61K8/34A61K8/345A61K8/42A61K8/4946A61K8/60A61K8/63A61K8/645A61K8/65A61K8/678A61K8/68A61K8/735A61K8/86A61K8/922A61K8/9711A61K8/9722A61K8/9741A61K8/9789A61K8/9794A61K8/99A61K2800/85A61K2800/782A61K2800/5922A61K2800/49A61K2800/48
Inventor 杨登亮刘德海戴嘉彬江兰兰李华真林盛杰张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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