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A kind of active collagen skin care composition and preparation method thereof

A collagen and active technology, used in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as low temperature precipitation of antiseptic ingredients, and achieve the effect of ensuring invariance and repairing skin

Active Publication Date: 2022-07-26
浙江珂瑞康生物医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the deficiencies in the prior art, the first object of the present invention is to provide an active collagen skin care composition, which uses a high concentration of active collagen as the single active ingredient in the composition, and through the compounding of antiseptic ingredients, Solve the defect of low-temperature precipitation of antiseptic components, and do not need to add flavors and anti-allergic agents

Method used

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  • A kind of active collagen skin care composition and preparation method thereof
  • A kind of active collagen skin care composition and preparation method thereof
  • A kind of active collagen skin care composition and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0036] Preparation steps of preservative mixture: 1,2-pentanediol, methylparaben, propylparaben, bis(hydroxymethyl)imidazolidinyl urea and IPBC are heated at 30-40°C Mix and dissolve to obtain a preservative mixture, which is cooled to below 20°C;

[0037] Preparation steps of active collagen solution: dissolving active collagen in water to obtain active collagen solution;

[0038] The preparation steps of the active collagen skin care composition: adding the preservative mixture into the active collagen solution, and mixing until transparent.

[0039] Preservation step: the obtained active collagen skin care composition is stored at 0-20°C.

Embodiment 1-4

[0041] The composition and mass percentage (%) of table 1 embodiment 1-4

[0042]

[0043] The molecular weight of active collagen is 300 kDa.

Embodiment 1

[0046] Embodiment 1 Anticorrosion test conditions:

[0047] Original concentration of bacterial liquid (pathogenic bacteria): 3.4×10 8 CFU / mL

[0048] The bacterial content of the sample added to the sample is: 3.4×10 6 CFU / mL

[0049] Original concentration of bacteria liquid (mold and yeast): 3.9×10 8 CFU / mL

[0050] The bacterial content of the sample added to the sample is: 3.9×10 6 CFU / mL

[0051] Total number of sample colonies (CFU / g): 10CFU / mL

[0052] Total sample mold yeast (CFU / g): <1CFU / mL

[0053] Table 2 Anticorrosion test data of Example 1

[0054]

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Abstract

The invention discloses an active collagen skin care antiseptic system and a preparation method thereof. The active collagen skin care antiseptic system comprises the following components: active collagen 0.4-0.6%; methylparaben 0.05-0.15%; 1,2-pentanediol 0.99-5 %; bis(hydroxymethyl) imidazolidinyl urea 0.1-0.4%; IPBC 0.05-0.1%; the balance is water; the preparation method comprises: mixing 1,2-pentanediol, methylparaben, bis( Hydroxymethyl)imidazolidinyl urea and IPBC are mixed and dissolved to obtain a preservative mixture, which is cooled; the active collagen is dissolved in water to obtain an active collagen solution; the preservative mixture is added to the active collagen solution, and the mixture is obtained after mixing; The anti-corrosion system uses high-concentration active collagen as a single active ingredient in the anti-corrosion system, and through the compounding of the anti-corrosion components, the defect of low-temperature precipitation of the anti-corrosion components is solved, and no flavor and anti-sensitizer are required.

Description

technical field [0001] The invention relates to an active collagen skin care composition and a preparation method thereof, belonging to the technical field of natural skin care compositions. Background technique [0002] Active collagen is an important functional substance that constitutes the animal body, exists in various organs in the animal body, and plays a pivotal role in the regulation of the normal physiological functions of each organ. In human skin, active collagen is present throughout the dermis, giving shape to the skin, and plays a major role in forming the skin that covers and protects the entire body. After research, the extracted natural active collagen has a good moisturizing effect on the skin, improving dry skin, increasing skin elasticity, anti-aging and reducing wrinkles, repairing damaged skin, etc. However, due to its immature extraction technology, the yield is small. Usually a small amount is added to skin care products. [0003] Active collagen n...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/65A61K8/49A61K8/44A61K8/37A61K8/34A61Q19/00A61Q19/08
CPCA61Q19/00A61Q19/08A61K8/345A61K8/37A61K8/44A61K8/4946A61K8/65A61K2800/524A61K2800/592A61K2800/30
Inventor 镇晓华张灿
Owner 浙江珂瑞康生物医疗科技有限公司
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