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Drug abortion method for dogs

A drug and dog technology, applied in the medical and health field, can solve the problems of stray dogs not being taken seriously, safety hazards, affecting urban sanitation, etc.

Inactive Publication Date: 2019-03-19
中国人民解放军66399部队
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Stray dogs also often attack other animals and even humans, which poses a considerable safety hazard. Their excrement will also affect urban sanitation. If they are not properly disposed of after death, the corpses will rot and smell and pollute the environment. The resulting disease spread and abuse Problems with culling, public safety and more are getting worse
[0003] How to effectively regulate the breeding behavior of stray dogs is a very difficult problem that is not taken seriously. At present, the method used in various places in China is to sterilize dogs, but the current situation is that the sterilization of stray dogs does not cannot be widely promoted
The reason is that on the one hand, it is difficult to capture stray dogs. On the other hand, the cost of dog sterilization is also high, and there are certain risks, especially during the anesthesia process of sterilization surgery, it is easy to be infected, and even life-threatening canine

Method used

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  • Drug abortion method for dogs
  • Drug abortion method for dogs
  • Drug abortion method for dogs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] S1: Drug screening, four drugs, mifepristone, diethylstilbestrol, long-acting 15-methyl-PGF2a and alepristone, were used as drugs for clinical pregnancy termination tests in canine laboratories;

[0040] S2: Determination of optimal pregnancy termination drugs in dogs,

[0041] Divide 25 beagle dogs about one year old and 25 days pregnant into 5 groups with 5 dogs in each group, of which 1 group is the control group, and the other 4 groups are the experimental group, and the test dogs in the 4 experimental groups correspond to Taking mifepristone, diethylstilbestrol, long-acting 15-methyl PGF2a and alepristone four kinds of medicines, the dosage of each test dog is 10 mg per kilogram of body weight, record the initial total amount of embryos and The average plasma progesterone content, and the average plasma progesterone content, the number of normal embryos and the number of abnormal embryos in each group were detected at intervals of 5 days.

[0042] Table 1 The aver...

Embodiment 2

[0049] S3: Evaluation of the relationship between the efficacy of optimal pregnancy termination drugs in dogs and the duration of pregnancy,

[0050] Set up 7 experimental groups, each with 5 beagle dogs about one year old, and the gestation time of the 7 experimental group beagle dogs are 30 days, 35 days, 40 days, 45 days, 50 days, 55 days, 60 days Day, the test dogs in the 7 experimental groups were given alepristone according to the amount of 10 mg per kilogram of body weight, and the initial total amount of embryos in each group and the number of normal embryos and abnormal embryos after taking alepristone for 25 days were recorded respectively. .

[0051] Table 3 Experimental dog embryonic development

[0052]

[0053] Analysis of experimental results: It can be seen from Table 3 that alepristone has a long range of effective pregnancy termination, and is effective from the early to the end of pregnancy. After taking alepristone in the test dogs within 45 days of pr...

Embodiment 3

[0055] S4: Evaluation of the optimal safe dosage of pregnancy termination drugs in dogs,

[0056] 14 experimental groups were set up, each group consisted of 5 beagle dogs about one year old and gestation time of 30 days, and the test dogs in the 14 experimental groups were divided into 7mg, 8mg, 9mg, 10mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg, 80mg, 90mg, 100mg, and 110mg of alepristone were administered, and the number of test dogs with abnormal physiological parameters after taking the drug for each group of test dogs was recorded for 1 hour; In the experimental group, the initial total number of embryos and the number of normal embryos and abnormal embryos after 25 days of taking alepristone were recorded in each group, and the miscarriage rate was calculated.

[0057] Table 4 The test results of the maximum safe dose of the test dog pregnancy termination drug alepristone

[0058]

[0059]

[0060] Table 5 Test results of effective dosage of test dog pregnancy termina...

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Abstract

The invention discloses a drug abortion method for dogs. The method comprises the five steps of drug screening, determination of an optimal pregnancy termination drug for dogs, assessment of a relationship between the action efficiency of the optimal pregnancy termination drug for dogs and the pregnancy time, assessment of the safety dosage of the optimal pregnancy termination drug for dogs and clinical trials in public places. According to the method, a complete set of implementation steps for drug abortion of dogs is involved and comprises screening of pregnancy drugs for dogs, drug safety assessment, putting in the public places and the like, and on the premise of ensuring the life health of the dogs, a drug putting mode is provided; the method is simple in operation and low in cost, isconveniently applied and implemented in the public places, and provides a new approach to regulation of the number of stray dogs.

Description

technical field [0001] The invention relates to the field of medical and health technologies, in particular to a medical abortion method for dogs. Background technique [0002] With the improvement of people's living standards, more and more families keep pet dogs. On the one hand, the abandonment of dogs and the disorderly breeding of stray dogs caused by people's irresponsible breeding behavior have caused the increasing number of stray dogs in cities in recent years, which has become a very serious social problem. Due to the harsh living environment of stray dogs, they cannot be regularly immunized, dewormed, and disinfected, and the probability of carrying viruses, bacteria, and parasites is much higher than that of domestic dogs. Stray dogs also often attack other animals and even humans, which poses a considerable safety hazard. Their excrement will also affect urban sanitation. If they are not properly disposed of after death, the corpses will rot and smell and pollu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H20/10
CPCG16H20/10
Inventor 余春刘国华樊海霞李修贤单维徐卫宾杨伟腾邹学明
Owner 中国人民解放军66399部队
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