A method for detecting children's Huaji granules

Abstract

Disclosed is a quality control method for infantile accumulation-eliminating granules. The method comprises: using thin-layer chromatography to perform qualitative identification on parched Crataegi fructus and Pharbitidis semen in infantile accumulation-eliminating granules; using high-performance liquid chromatography to determine the content of an activation component, arecoline, in the infantile accumulation-eliminating granules to carry out quantitative control; and using a potentiometric titration method to determine the content of organic acids in the infantile accumulation-eliminating granules. The method of the present invention is simple, has a good degree of separation, strong specificity and good reproducibility, thereby effectively guaranteeing the quality and curative effect of the infantile accumulation-eliminating granules, and having very strong practicality.

Description

technical field [0001] The invention belongs to the technical field of medicine quality detection, and in particular relates to a detection method for Xiaoer Huaji granules. Background technique [0002] The prescription of Xiaoer Huaji Granules consists of six medicinal materials, including Jiaohazhawthorn, fried malt, Liushenqu (stir-fried bran), fried betel nut, fried chicken neijin, and fried morning glory seed, which are not included in the 2015 edition of Chinese Pharmacopoeia. [0003] Chinese invention application document CN101229329A discloses a Chinese patent medicine Huaji Tablet and its production process, which is the prescription of Huajisan: 166.67g burnt hawthorn, 166.67g fried malt, 166.67g Liushenqu (bran fried), 166.67g fried betel nut , 166.67g fried chicken inner gold, 166.67g fried morning glory, mainly used for the treatment of disharmony between the spleen and stomach in children, stopping eating and stopping breastfeeding, accumulating lumps, disten...

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