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Evaporation drying device for paclitaxel liposome

A technology of evaporative drying and liposomes, which is applied in the field of evaporative drying devices for paclitaxel liposomes, can solve problems such as easy leakage accidents, and achieve the effects of reducing leakage accidents, increasing weight, and enhancing sealing performance

Active Publication Date: 2019-05-10
CHONGQING MEDICAL & PHARMA COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented method improves the gasket design for prevention of leaks when connecting two pipes together by creating an improved gap where there are no spaces around them. It also reduces any chance of gas escaping during installation due to imperfections such as cracks caused by pressure differences across different parts of the system. Additionally, it simplifies assembly process while maintaining good performance over time.

Problems solved by technology

This patented problem addressed in this patents relates to improving the stability or compatibility of certain drugs during storage when they can cause side reactions such as inflammation (irritating pain) and breakdowns overtime due to changes caused by temperature fluctuations.

Method used

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  • Evaporation drying device for paclitaxel liposome
  • Evaporation drying device for paclitaxel liposome
  • Evaporation drying device for paclitaxel liposome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Basic as attached Figure 1~3 Shown:

[0032] The evaporative drying device of paclitaxel liposome comprises frame in the prior art, processing table, water bath 1, rotary bottle 4, bottle clamp 3, steam pipe 2 and two rubber sealing layers 21; water bath 1 and frame All are located on the processing table, and the steam pipe 2 is positioned on the frame. In order to facilitate the insertion of the steam pipe 2 into the rotary bottle 4, the diameter of the mouth of the steam pipe 2 is less than the diameter of the steam pipe 2 body. The outer wall of the nozzle of the steam pipe 2 is glued with a rubber sealing layer 21 . The bottle neck inner wall of the rotary bottle 4 is also bonded with a rubber sealing layer 21. When the steam pipe 2 is inserted into the rotary bottle 4, the two rubber sealing layers 21 are in contact with each other, thereby realizing the sealing of the two; and the rotary bottle 4 can be stretched into In the water bath 1, the water in the wate...

Embodiment 2

[0039] The difference between this embodiment and Embodiment 1 is that the connecting strip 33 is a deformable elastic material, such as Figure 4 As shown, the connecting strip 33 is provided with a cavity 331, and the cavity 331 is provided with a soft bag 332. The soft bag 332 in this embodiment can be a thicker PVC plastic bag, and its outer wall is wrapped with a cotton cloth layer; the soft bag 332 Both sides are bonded to the cavity wall of the cavity 331; a metal strip 333 is stuck on the soft bag 332, and the soft bag 332 is filled with supersaturated solution sodium acetate 3321 (note that it cannot be filled when filling); the entire connecting strip 33 is mainly It is formed by supporting the metal strip 333.

[0040] During use, the hot gas in the water bath 1 gushes out from the gap 121, and the hot gas contacts the connecting bar 33, and then heats the supersaturated solution sodium acetate 3321 in the connecting bar 33, and the supersaturated solution sodium ac...

Embodiment 3

[0042] In this embodiment, on the basis of Embodiment 2, a through hole is provided on the wall of the cavity 331, and the hot air in the water bath can enter the cavity 331 through the through hole, further speeding up the contact speed between the soft bag 332 and the hot air.

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Abstract

The invention relates to the technical field of liposome processing and specifically discloses an evaporation drying device for paclitaxel liposome. The evaporation drying device comprises a bottle clamp, an evaporation tube and a rubber sealing layer located on an outer wall of the evaporation tube; the middle or upper part of the rubber sealing layer is bulged outward so as to form a bulged ring; the bottle clamp comprises a first C-shaped clamping wall and a second C-shaped clamping wall located under the first C-shaped clamping wall; a connecting strip is arranged between the first C-shaped clamping wall and the second C-shaped clamping wall; a counterweight bulge is arranged on the inner side of the first C-shaped clamping wall. The scheme is capable of solving the problem in the prior art that leakage accident is likely to occur because the rotating bottle and the evaporation tube are sealed through the contact of respective rubber sealing layers.

Description

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Claims

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Application Information

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Owner CHONGQING MEDICAL & PHARMA COLLEGE
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