A blood coagulation test system driven by sound waves

A blood coagulation and testing system technology, applied in the direction of measuring devices, flow characteristics, instruments, etc., can solve the problems of slow speed, high cost, and many samples, and achieve high reaction efficiency, less samples, and lower testing costs.

Active Publication Date: 2020-07-28
XI AN JIAOTONG UNIV
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  • Abstract
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Problems solved by technology

However, the current blood coagulation detection equipment is high in cost, slow in speed, and requires many samples.

Method used

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  • A blood coagulation test system driven by sound waves
  • A blood coagulation test system driven by sound waves
  • A blood coagulation test system driven by sound waves

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Embodiment Construction

[0017] Below in conjunction with accompanying drawing, the present invention is described in further detail:

[0018] see figure 1 , 2 , the present invention is an acoustofluidic device suitable for blood coagulation testing of micro-droplets, comprising a hollow glass substrate 1, an interdigital transducer 2, a piezoelectric plate 3, a blood movement reaction cell 4, a detection electrode 5, a height Adjust the bracket 6 and the image acquisition system 7, wherein the interdigital transducer 2 is sputtered or evaporated on the hollow glass substrate 1 through micromachining technology, the blood reaction pool 4 is connected to the piezoelectric plate through bonding technology, and the detection electrode 5 is a spring structure, which is directly clamped on the blood movement reaction pool 4, and the height adjustment bracket is used to adjust the distance between the blood movement reaction pool 4 and the image acquisition system 7, so as to facilitate clear observation ...

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Abstract

The invention discloses a blood coagulation test system driven by sound waves. The blood coagulation test system driven by sound waves comprises a hollow glass substrate, an interdigital transducer, apiezoelectric plate, a blood movement reaction tank, a detection electrode and an image acquisition and analysis system, and an interdigital electrode is evaporated on the substrate; the piezoelectric plate is placed on the interdigital electrode; an annular blood reaction tank obtained through cutter cutting is in bonding with the piezoelectric plate through surface treatment; the detection electrode is fixed to the reaction tank through a fixing spring; and by adjusting the position of a bracket, it is ensured that the image acquisition system is located at a suitable position, and the movement condition of blood can be recorded in real time. The blood coagulation test system driven by sound waves is simple and convenient in equipment, the integration level is high, required samples areless, energy consumption is lower, the reaction efficiency is high, open type reaction is easy to operate and maintain, and detection and analysis of various parameters in the blood coagulation process can be realized.

Description

technical field [0001] The invention belongs to the technical field of applied micro-nano manufacturing, relates to a detection device for blood coagulation, and is a microfluidic test system suitable for rapid detection of blood coagulation. Background technique [0002] Applying micro-nano manufacturing technology, integrating functions such as acoustic wave drive, blood flow, and temperature measurement in a small volume, and integrating image detection and temperature control at the same time, can realize rapid detection of blood coagulation under constant temperature conditions. The microfluidic system formed by the micro-nano manufacturing technology is easy to be integrated with the detection circuit to realize the automation and miniaturization of the analytical instrument; the distributed design of the blood detection device and the driving device reduces the number of micro-nano manufacturing times and reduces the production cost. [0003] Blood coagulation detecti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/00G01N11/00G01N21/84
Inventor 郑腾飞刘玥王朝晖贾长风许朝萍
Owner XI AN JIAOTONG UNIV
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