36 results about "Blood coagulation test" patented technology

A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test chamber pivot element and is provided with a cartridge port for introducing a test sample into the test chamber,. Ferromagnetic agitator vane leaflets extend from an agitator pivot element supported by the test chamber pivot element intermediate the upper and lower major sides for rotational motion. The agitator vane leaflets can be swept, in response to an external magnetic field, through the test sample in the absence of coagulation. A timer is started when the agitator movement is commenced whereupon the agitator moves freely. Resistance to agitator movement due to coagulation is detected, and the coagulation time is measured.

In a biomedical chip for blood coagulation tests and its manufacturing method and use, the biomedical chip comprises a substrate layer, a middle layer, and a cap layer, engaged and stacked with each other to define a microfluidic channel which has a first inlet and an outlet of the microfluidic channel respectively. A mixing interval is expanded outward from the microfluidic channel and interconnected to a second inlet, and has an interconnect portion and a capillary portion disposed between the substrate layer and the cap layer, and more specifically disposed around the periphery of the interconnect portion. With the biomedical chip having the substrate layer and cap layer made of a hydrophilic material, the blood and the reagent can be driven automatically by the capillary force of the microfluidic channel to flow and mix with each other, and the hydrophilic capillary force can be permanently maintained.

A system and method for determining a coagulation time, e.g., thrombin time, PT, aPTT, and ACT, of a blood sample deposited in a test cartridge is disclosed. The test cartridge comprises a blood receptacle that is open to the atmosphere into which a blood sample is to be deposited, a vacuum port that is open to atmosphere, and a spiral capillary within the test cartridge having a capillary length and cross-section area, a first capillary end of the spiral capillary open to the blood receptacle and a second capillary end of the spiral capillary open to the vacuum port, whereby the spiral capillary is closed to atmosphere. When a blood sample is deposited in the blood receptacle, a vacuum is drawn through the vacuum port and the blood is drawn through the spiral capillary until coagulation occurs. A pressure change is detected, and the coagulation time is measured.

The invention discloses a portable blood coagulation test card. The portable blood coagulation test card comprises a bottom layer with a printed detection electrode, a middle layer through which a blood sample flows, and an upper layer for blood siphon, wherein the upper layer, the middle layer and the bottom layer are stuck in sequence, the upper layer is provided with a sample add area for adding a blood sample, the middle layer is provided with at least two test channels, one end of the test channel is communicated with the sample add area, the other end of the test channel is provided witha test area, one test channel is a delay channel, an obstacle is arranged in the middle in the delay channel, the end part of the test area is provided with an air hole communicated with the upper layer, the inner side wall of the bottom layer is provided with an electrode conduction area connected with the test area, and the end part of the electrode conduction area is inserted into a test hostto be detected. The portable blood coagulation test card can deliver a detection result within one or two minutes through a drop of fingertip blood or venous whole blood only, thereby being convenientto test, being accurate and sensitive, being portable, and being convenient and flexible to use.

The invention discloses a full-automatic Newcastle disease detector and relates to the technical field of animal medical equipment. The full-automatic Newcastle disease detector comprises a red blood cell supply unit, a virus liquid supply unit, a reagent supply unit, a reaction plate production unit, a vision interpretation unit, an interpretation region motion unit, a suction head supply unit, a sample feeding region motion unit and a single-shaft double-sliding block motion unit, wherein all the units are mounted on a base. According to the full-automatic Newcastle disease detector, Newcastle disease blood coagulation test and Newcastle disease blood coagulation inhibition test can be simultaneously carried out on Newcastle disease virus samples. The full-automatic Newcastle disease detector is simple and compact in structure and is suitable for batch, rapid and effective tests.

The blood coagulation test device according to the present invention is provided with: a container into which test-object blood is placed; a stirring part for stirring the test-object blood in the container; an elastic body capable of deforming in response to a force received through stirring of the test-object blood from the stirring part, the elastic body being connected to the stirring part; acontrol part for transmitting a predetermined rotary motion to the stirring part and causing the stirring part to rotate in reciprocating fashion in a circumferential direction by rotating the elasticpart in reciprocating fashion about an axis of the stirring part as a rotational axis and controlling the reciprocating rotation in a position separated a predetermined diameter from the rotational axis; and a measurement part for measuring the rotation angle pertaining to the reciprocating rotation of the stirring part.

The invention provides a thromboplastin reagent comprising: tissue factor, a phospholipid and a polyphosphate that acts as a blocker of tissue factor pathway inhibitor (TFPI). Also provided are a composition for promoting clotting comprising polyphosphate, and a reagent for a clotting assay also comprising polyphosphate together with an activator of clotting. Methods for stopping or slowing wound bleeding and fibrinolysis using compositions comprising polyphosphate are also disclosed.

The invention relates to the technical field of medical instruments, and particularly relates to a blood coagulation reagent management method and system. The management system comprises a first reagent container, the first reagent container is provided with at least two first reagent containing cavities, and the at least two first reagent containing cavities are independently arranged so as to contain set reagents needed by blood coagulation test items in a one-to-one correspondence mode so that the first reagent container can independently complete the blood coagulation test items of the preset number of times. Therefore, reagents can be managed through each blood coagulation test item in the reagent management and detection process, and a situation that one reagent is still available and the other reagent is insufficient in the traditional method is avoided so that the detection efficiency is improved, and the reagent cost is saved. Meanwhile, the blood coagulation test items of thepreset number of times are independently completed through the first reagent container, the reagents needed by the corresponding blood coagulation test items can be conveniently loaded and replaced at a time, and the reagent loading and replacing efficiency of a user is effectively improved.

A coagulation test device for measuring clotting time and clot characteristics of a whole blood sample under different hemostatic conditions. Results of the test are used as an aid in management of patients with coagulopathy of unknown etiology in order to help the physician determine appropriate clinical action to arrest bleeding in a patient.

The invention relates to the technical field of quality control of blood coagulation test items, in particular to a multi-level quality control product and a preparation method thereof and application of the multi-level quality control product to thromboelastogram detection. The thrombelastogram quality control product provided by the invention has a level 1 (normal value), a level 2 (high coagulation) and a level 3 (low coagulation), covers various states such as clinical normal coagulation, high coagulation, low coagulation, small Angle and the like, simulates a clinical actual detection environment, is combined with a thrombelastogram instrument, a matched reagent and a calcium chloride solution for use, and can carry out quality control or detection system evaluation on a thromboelastogram detection system. The thrombelastogram quality control product can be applied to quality control practice operation of a thrombelastogram detection system composed of equipment and matched reagents, and the reliability of clinical sample detection results is guaranteed.

The invention discloses a blood coagulation test system driven by sound waves. The blood coagulation test system driven by sound waves comprises a hollow glass substrate, an interdigital transducer, apiezoelectric plate, a blood movement reaction tank, a detection electrode and an image acquisition and analysis system, and an interdigital electrode is evaporated on the substrate; the piezoelectric plate is placed on the interdigital electrode; an annular blood reaction tank obtained through cutter cutting is in bonding with the piezoelectric plate through surface treatment; the detection electrode is fixed to the reaction tank through a fixing spring; and by adjusting the position of a bracket, it is ensured that the image acquisition system is located at a suitable position, and the movement condition of blood can be recorded in real time. The blood coagulation test system driven by sound waves is simple and convenient in equipment, the integration level is high, required samples areless, energy consumption is lower, the reaction efficiency is high, open type reaction is easy to operate and maintain, and detection and analysis of various parameters in the blood coagulation process can be realized.

The invention discloses a two-way light splitting blood coagulation test device. The device comprises a base plate and a first light source device arranged on the base plate. The base plate is successively connected to a light collecting device for collecting polychromatic light emitted by the first light source device, a light splitting device for dividing the polychromatic light into monochromatic light with different wavelengths, a light guiding device for conducting the monochromatic light to a test area and a first measuring device for measuring the optical signal of an object to be tested. The light splitting device comprises a two-way light splitting component so as to realize the multi-project detection of a sample. The polychromatic light is converted into the monochromatic lightwith different wavelengths to be detected through the light splitting device and the light guiding device, and a motor and a driver which filter rotation wheel movement in a traditional blood coagulation analyzer depends on are eliminated. Working is reliable and cost is low.

The invention discloses a blood coagulation time calculation method, device and system and a readable storage medium. The method comprises the following steps: obtaining a current amplitude data segment generated by the movement of a small steel ball in a blood coagulation test according to a preset period, and calculating a median and a first kurtosis set corresponding to a wave crest set according to the wave crest set in the current amplitude data segment; comparing the first kurtosis set with a preset kurtosis threshold to obtain a first comparison result, and based on the first comparison result, obtaining a second kurtosis set and a third kurtosis set corresponding to the first two amplitude data segments; comparing the second kurtosis set and the third kurtosis set with a preset kurtosis threshold to obtain a second comparison result, and comparing the median with a blood coagulation threshold based on the second comparison result to obtain a third comparison result; based on the first comparison result, the second comparison result and the third comparison result, blood coagulation time is determined; the blood coagulation time is determined according to the three continuous amplitude data segments, and the accuracy of determining the blood coagulation time is improved.