A kind of soft capsule for treating children with acute bronchitis cough

A technology for acute bronchitis and soft capsules, which is applied in the directions of capsule delivery, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., and can solve problems such as difficulty in completion, softening of capsule shells, and stratification of contents. , to achieve the effect of uniform filling liquid, long shelf life and stable quality

Active Publication Date: 2021-08-24
北京东方运嘉药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hydrophilic drugs and drugs with high water content should not be made into soft capsules, which are prone to various problems, including stratification of the contents, softening of the capsule shell, and leakage.
Therefore, although soft capsules have many advantages over other oral solid preparations, such as fast onset of action, high bioavailability, easy administration, and suitable for children, etc., many proprietary medicines, especially Chinese patent medicines, still do not have soft capsule formulations. For example, Xiaoer Chiqiao Granules, Xiaoer Kechuanling Granules, Xiaoer Quick-acting Ganmao Granules, etc. Although these medicines are very effective, it is very troublesome and sometimes even difficult to administer these medicines to children. It can be effectively dealt with at the initial stage, which also makes parents very worried

Method used

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  • A kind of soft capsule for treating children with acute bronchitis cough
  • A kind of soft capsule for treating children with acute bronchitis cough
  • A kind of soft capsule for treating children with acute bronchitis cough

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Get 1000g of Scutellaria baicalensis, 888g of golden buckwheat, 888g of loquat leaves (honey roasted), 666g of Fritillaria japonicus, 666g of Polygonum cuspidatum, and 334g of licorice into a multifunctional extraction tank, add distilled water of 15 times the amount (W / L) of the raw material drug, and heat up to boiling. Decoct for 2 hours, the steam pressure is maintained at 0.03MPa, the decoction is filtered through a 200-mesh sieve, and the filtrate is pumped into the storage tank; add 7 times the amount (W / L) of distilled water to the extraction tank, heat up to boiling, and decoct. Boil for 1 hour, keep the steam pressure at 0.05MPa, filter the decoction through a 200-mesh sieve, and pump the filtrate into the storage tank; combine the two decoctions, pump the decoction into the double-effect energy-saving concentration tank, and close the feed valve , for double-effect concentration, the first-effect concentration temperature is 50-70°C, the vacuum degree of the f...

Embodiment 2

[0074] Get 1000g of Scutellaria baicalensis, 888g of golden buckwheat, 888g of loquat leaves (honey roasted), 666g of Fritillaria japonicus, 666g of Polygonum cuspidatum, and 334g of licorice into a multifunctional extraction tank, add distilled water with 12 times the amount (W / L) of the raw material drug, and heat up to boiling. Decoct for 2 hours, the steam pressure is maintained at 0.03MPa, the decoction is filtered through a 200-mesh sieve, and the filtrate is pumped into the storage tank; add 10 times the amount (W / L) of distilled water to the extraction tank, heat up to boiling, and decoct Boil for 0.5 hours, keep the steam pressure at 0.05MPa, filter the decoction through a 200-mesh sieve, and pump the filtrate into the storage tank; combine the two decoctions, pump the decoction into the double-effect energy-saving concentration tank, and close the feed valve , for double-effect concentration, the first-effect concentration temperature is 50-70°C, the vacuum degree of ...

Embodiment 3

[0076] Get 530g of Scutellaria baicalensis, 474g of golden buckwheat, 474g of loquat leaves (honey roasted), 363g of Fritillaria japonicus, 363g of Polygonum cuspidatum, and 197g of licorice into a multifunctional extraction tank, add distilled water of 20 times the amount (W / L) of the raw material drug, and heat up to boiling. Decoct for 1 hour, the steam pressure is maintained at 0.03MPa, the decoction is filtered through a 200-mesh sieve, and the filtrate is pumped into the storage tank; add 7 times the amount (W / L) of distilled water to the extraction tank, heat up to boiling, and decoct Boil for 1 hour, keep the steam pressure at 0.05MPa, filter the decoction through a 200-mesh sieve, pump the filtrate into the storage tank, combine the two decoctions, pump the decoction into the double-effect energy-saving concentration tank, and close the feed valve , for double-effect concentration, the first-effect concentration temperature is 50-70°C, the vacuum degree of the first-ef...

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Abstract

The invention relates to a soft capsule for treating children with acute bronchitis cough and a preparation method thereof. The soft capsule is made from scutellaria baicalensis, golden buckwheat, loquat leaves, Fritillaria japonicus, Polygonum cuspidatum and licorice as raw materials. The preparation has excellent cough-relieving performance and contains no sugar, which is very suitable for children.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, more specifically, a soft capsule for treating cough caused by acute bronchitis in children. Background technique [0002] Acute bronchitis in children is a common respiratory disease in children. The disease is often secondary to upper respiratory tract infection and is often an early manifestation of pneumonia. There are also early symptoms or complications of acute infectious diseases in children such as measles, whooping cough, typhoid fever, and scarlet fever. [0003] At the beginning of the disease, it manifested as symptoms of upper respiratory tract infection, fever, runny nose, and cough. The cough gradually worsened and there was sputum. It was white sticky sputum at first, and turned into yellow purulent sputum after a few days. Some children have a hoarse throat and a severe cough in the morning and evening, and often spit out food due to coughing. It is often accompani...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A61K36/8966A61K9/48A61K47/10A61K47/18A61K47/42A61K47/22A61P11/14
CPCA61K9/4816A61K9/4825A61K9/4858A61K9/4866A61K36/539A61K36/70A61K36/704A61K36/73A61K36/8966A61K2236/331A61K2236/39A61P11/14A61K2300/00
Inventor晁恩祥晁燕曾风英王小花王宏图
Owner北京东方运嘉药业有限公司