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Composition for treating frog torticollis and application of composition

A technology of composition and content, which can be applied to drug combinations, medical preparations containing active ingredients, nervous system diseases, etc. The risk of head disease, the effect of improving immunity, and ensuring economic benefits

Inactive Publication Date: 2019-08-23
SICHUAN AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a composition for treating frog head tilt and its application. Based on the self-discovered pathogen distribution and transmission rules, it breaks through the limitations of traditional veterinary drug use. The comprehensive method effectively solves the problem that the existing antibiotics are not effective in the treatment of frog tilting head disease

Method used

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  • Composition for treating frog torticollis and application of composition
  • Composition for treating frog torticollis and application of composition
  • Composition for treating frog torticollis and application of composition

Examples

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Effect test

Embodiment 1

[0036]A composition for treating frog head tilt, comprising sulfadiazine, trimethoprim, doxycycline hydrochloride, sodium bicarbonate and ficus polysaccharide.

[0037] According to every kilogram of body weight of the frogs administered, the content of the sulfadiazine is 0.07g, the content of the doxycycline hydrochloride is 0.013g, and the content of the ficus polysaccharide is 0.3g; the trimethoprim The mass ratio between pyridine and the sodium bicarbonate and the sulfadiazine is 1:5 and 1:1 respectively.

Embodiment 2

[0039] A composition for treating frog head tilt, comprising sulfadiazine, trimethoprim, doxycycline hydrochloride, sodium bicarbonate and ficus polysaccharide.

[0040] According to every kilogram of body weight of the frogs administered, the content of the sulfadiazine is 0.15g, the content of the doxycycline hydrochloride is 0.03g, and the content of the fig polysaccharide is 0.5g; the trimethoprim The mass ratio between pyridine and the sodium bicarbonate and the sulfadiazine is 1:5 and 1:1 respectively.

Embodiment 3

[0042] A composition for treating frog head tilt, comprising sulfadiazine, trimethoprim, doxycycline hydrochloride, sodium bicarbonate and ficus polysaccharide.

[0043] According to every kilogram of body weight of the frogs to be used, the content of the sulfadiazine is 0.085g, the content of the doxycycline hydrochloride is 0.017g, and the content of the fig polysaccharide is 0.35g; the trimethoprim The mass ratio between pyridine and the sodium bicarbonate and the sulfadiazine is 1:5 and 1:1 respectively.

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Abstract

The invention relates to a composition for treating frog torticollis and application of the composition. The composition comprises sulfadiazine, trimethoprim, doxycycline hydrochloride, sodium bicarbonate and ficus carica polysaccharides. After frogs with torticollis are fed with the composition mixed with bait, the cure rate can reach 80% or above. After frogs infected with pathogenic bacteria but not attacked by the torticollis are fed with an orally taken material mixed with the bait, the incidence rate can be reduced from 90% to 2.5% or below. The composition overcomes the clinical medication bias of the traditional veterinary medicine for frog torticollis, finds that the torticollis accords with combined medication indications, reveals the root cause of the poor treatment effect of existing drugs that the blood brain barrier cannot be effectively broken through, and truly achieves systemic therapy of the frog torticollis, thereby effectively improving the cure rate of the frog torticollis.

Description

technical field [0001] The invention relates to the technical field of frog disease prevention and control, in particular to a composition for treating frog head tilt and application thereof. Background technique [0002] Frog head tilt disease is a bacterial disease that broke out with the expansion of the frog breeding industry. The typical symptoms are head tilt, eyeball cataract, and movement disorders. The disease has a high fatality rate, spreads rapidly, and occurs year after year. Poor, seriously threatening the frog breeding industry. According to research by scholars, Elizabeth Kingiamilicola and Elizabeth Kingiameningoseptica are the most common pathogens causing the disease. The two bacteria have similar properties, similar pathogenic mechanisms, and similar pathogenic symptoms. They are often confused in identification. Some scholars even believe that the only bacteria that causes frogs to become sick is Elizabeth mil. The identification result is an identific...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00A61P31/04A61P25/00A61K31/63A61K31/505A61K31/65A61K31/715
CPCA61K31/505A61K31/63A61K31/65A61K31/715A61K33/00A61P25/00A61P31/04A61K2300/00
Inventor 耿毅秦振阳汪开毓赵若璇白明焕欧阳萍陈德芳黄小丽
Owner SICHUAN AGRI UNIV
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