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Hydrogel microsphere containing ellagic acid and preparation method thereof

A technology of hydrogel microspheres and ellagic acid, which is applied in the field of daily chemical industry, can solve the problem of difficult cosmetic application of ellagic acid, and achieve the effects of reducing tyrosinase activity, reducing melanin content and reducing wrinkles

Inactive Publication Date: 2019-10-15
SHANGHAI INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the above-mentioned problems in the prior art, the object of the present invention is to provide a kind of hydrogel microsphere containing ellagic acid and preparation method thereof, to solve the technical problem that ellagic acid is difficult to carry out cosmetic application in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A hydrogel microsphere containing ellagic acid for whitening and moisturizing functions, comprising a core material and a wall material, the wall material is coated on the outside of the core material, and the core material contains ellagic acid, a moisturizing agent, and an antioxidant and preservatives, and the wall material is a hydrogel formed by cross-linking sodium alginate and calcium chloride. The moisturizing agent is sodium hyaluronate, the antioxidant is vitamin E, and the preservative is propylparaben. The mass ratio of core material and wall material is 3:1. The mass ratio of ellagic acid, humectant, antioxidant and preservative in the core material is: 0.2:3.0:0.2:0.2.

[0032] The specific steps of the hydrogel microspheres containing ellagic acid include: adding 50g of distilled water to a beaker, heating it to 80-90°C with a water bath, and adding 1.2g of sodium alginate under the stirring condition of 600r / min , stir for 30 minutes, disperse evenly, ...

Embodiment 2

[0035] A hydrogel microsphere containing ellagic acid for whitening and moisturizing functions, comprising a core material and a wall material, the wall material is coated on the outside of the core material, and the core material contains ellagic acid, a moisturizing agent, and an antioxidant and preservatives, and the wall material is a hydrogel formed by cross-linking sodium alginate and calcium chloride. The moisturizing agent is sodium hyaluronate, the antioxidant is vitamin E, and the preservative is propylparaben. The mass ratio of core material and wall material is 4:1. The mass ratio of ellagic acid, humectant, antioxidant and preservative in the core material is: 0.3:4.0:0.3:0.2.

[0036] The specific steps of the hydrogel microspheres containing ellagic acid include: adding 50g of distilled water to a beaker, heating it to 80-90°C with a water bath, and adding 1.2g of sodium alginate under the stirring condition of 600r / min , stir for 30 minutes, disperse evenly, ...

Embodiment 3

[0039] A hydrogel microsphere containing ellagic acid for whitening and moisturizing functions, comprising a core material and a wall material, the wall material is coated on the outside of the core material, and the core material contains ellagic acid, a moisturizing agent, and an antioxidant and preservatives, and the wall material is a hydrogel formed by cross-linking sodium alginate and calcium chloride. The moisturizing agent is sodium hyaluronate, the antioxidant is vitamin E, and the preservative is propylparaben. The mass ratio of core material and wall material is 5:1. The mass ratio of ellagic acid, humectant, antioxidant and preservative in the core material is: 0.4:5.0:0.4:0.2.

[0040]The specific steps of the hydrogel microspheres containing ellagic acid include: adding 50g of distilled water to a beaker, heating it to 80-90°C with a water bath, and adding 1.2g of sodium alginate under the stirring condition of 600r / min , stir for 30 minutes, disperse evenly, a...

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Abstract

The invention provides a hydrogel microsphere containing ellagic acid and a preparation method thereof. The hydrogel microsphere containing the ellagic acid is characterized by comprising a core material and a wall material, wherein the wall material wraps the core material; the core material contains ellagic acid, a humectant, an antioxidant and a preservative; and the wall material is hydrogel formed by crosslinking sodium alginate and calcium chloride. The hydrogel microsphere containing the ellagic acid obtained by the invention is applied on the face to reduce melanin deposition in a large area, and has the effects of whitening and moisturizing skins.

Description

technical field [0001] The invention belongs to the field of daily chemical industry, and relates to a hydrogel microsphere, specifically, an ellagic acid hydrogel microsphere capable of eliminating free radicals, reducing melanin content of melanocytes and tyrosinase activity and preparation thereof method. Background technique [0002] Long-term outdoor activities absorb ultraviolet rays or dark spots and spots of melanin deposits left by skin acne have always plagued most people, not only hindering the appearance, but also sometimes affecting health. [0003] Many whitening products are ineffective or expensive because of their low content or the ineffectiveness of the whitening substance itself. Ellagic acid is a natural active ingredient with multiple functions such as anti-oxidation, anti-aging, anti-ultraviolet, whitening and moisturizing. It has a strong ability to resist lipid peroxidation and capture free radicals, and can be used as an oxidation substrate to ensu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/11A61K8/20A61K8/49A61K8/73A61Q19/00A61Q19/02
CPCA61K8/11A61K8/20A61K8/498A61K8/733A61K2800/782A61Q19/00A61Q19/02
Inventor 宋晓秋倪佳慧叶琳
Owner SHANGHAI INST OF TECH
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