Micro total analysis chip and in-situ reaction method

A technology of micro-total analysis and in-situ reaction, which is applied in the direction of material analysis, material excitation analysis, and material analysis through optical means, which can solve the problems of loss of preset samples and deviation of analysis results, etc., to simplify complexity and improve reliability. controlling effect

Pending Publication Date: 2019-11-19
CHINA PETROLEUM & CHEM CORP +1
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the analysis, if the preset reagents are not protected, some of the preset reagents may be taken away due to the flow of the sample when the external sample to be tested is introduced into the micro-analysis chip, resulting in the loss of the preset samples, which in turn leads to analysis deviation of results

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Micro total analysis chip and in-situ reaction method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] This embodiment is used to illustrate a micro-total analysis chip pre-installed with a reagent solid reagent and an in-situ reaction method using the micro-total analysis chip.

[0054] Such as figure 1 As shown in (b), the KSCN solid is packaged with a soluble film by hot pressing to obtain a capsule, and then placed in the reaction pool of the micro total analysis chip. The soluble film used is a polyvinyl alcohol film with a thickness of 0.020 mm and a stable period of 5 s. The solution to be tested is introduced through the injection port and the flow channel of the micro total analysis chip. The soluble film remained intact for 5 s before the start of solution introduction, during which the solution was introduced and filled the reaction cell. After 5 s, the soluble film encapsulating the KSCN solid dissolved, and the solid sample in the film was released, and the Fe in the solution 3+ The solution was reacted to form a reddish-brown solution, which proved that ...

Embodiment 2

[0056] This embodiment is used to illustrate a micro-total analysis chip pre-installed with capsules packaged with different reagents and an in-situ reaction method using the micro-total analysis chip.

[0057] Such as figure 1 As shown in (c), the powdered yellow dye is encapsulated with a polyvinyl alcohol soluble film with a thickness of 0.023mm to obtain capsule a (stable period is 7s), and the powdered blue dye is encapsulated with a polyethylene film with a thickness of 0.046mm Capsule b was obtained by encapsulation with an alcohol-soluble film (the stability period was 3 minutes), and then the capsules a and b were simultaneously preset in the same reaction pool of the micro-total analysis chip. Introduce deionized water through the flow channel of the micro total analysis chip. During the 7 second period during the introduction of deionized water, the encapsulation film remained intact. After 7 seconds, the soluble film in capsule a began to dissolve, and the yellow...

Embodiment 3

[0059] This embodiment is used to illustrate a micro-total analysis chip pre-installed with capsules that simultaneously encapsulate reagents and capsules, and an in-situ reaction method using the micro-total analysis chip.

[0060] Such as figure 1 As shown in (b), the periodic acid solid is encapsulated with a polyvinyl alcohol soluble film with a thickness of 0.046mm to obtain capsule b (the stability period is 3min), and then the NaOH solid and capsule b are jointly used with a polyethylene film with a thickness of 0.023mm. Capsule a (with a stable period of 7s) was obtained by encapsulation with an alcohol-soluble film, and then the capsule a was preset in the reaction pool of the micro-total analysis chip. The phenolphthalein solution was introduced through the flow channel of the micro total analysis chip. The encapsulation membrane remains in place for a period of 7 seconds during liquid sample introduction. After 7 seconds, the soluble film in capsule a begins to di...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention relates to the field of micro total analysis chips, and discloses a micro total analysis chip and an in-situ reaction method. The micro total analysis chip comprises a reaction tank, a reagent and a soluble film used for packaging the reagent are arranged in the reaction tank, and the soluble film is dissolved after a certain stable period after being in contact with a liquid reagent. The micro total analysis chip provided by the invention has the packaged preset reagent, so that the preset operation of the reagent is simplified, the control difficulty of the amount of the presetreagent is reduced, and the application range of the preset reagent and the accuracy of an analysis result are improved.

Description

technical field [0001] The invention relates to the field of micro-total analysis chips, in particular to a micro-total analysis chip and an in-situ reaction method. Background technique [0002] Micro-full analysis system, also known as lab-on-a-chip, is an analysis technology designed to integrate all functions of the laboratory on a chip. It shows excellent prospects in the miniaturization, portability and automation of analysis technology, and has become a a major research hotspot. [0003] During the micro-total analysis process, there are often two or more reagents mixed and reacted. Due to the wide variety of reagents, and the types and quantities of reagents involved in different reactions are also different, various reagents are introduced into the micro-total analysis in real time. The reaction of the chip not only requires the overall arrangement of the position and introduction sequence of various reagents, which increases the complexity of the system, but also ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & AuthorityApplications(China)
IPC IPC(8): G01N21/01G01N21/31G01N21/25G01N21/3577G01N21/64G01N21/65
CPCG01N21/01G01N21/3103G01N21/251G01N21/3577G01N21/6402G01N21/65
Inventor姜慧芸孙冰冯俊杰赵磊文松石宁
OwnerCHINA PETROLEUM & CHEM CORP