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Use of ginkgo seed ketone ester in preparation of drugs for prevention and treatment of gout

A technology of ginkgo ketone ester and ginkgo ketone, which is applied in the field of medicine, can solve the problems that patients cannot accept long-term use of western medicine, recurrent gout attacks, large side effects of gout, etc., and achieve huge social and economic benefits, improvement of uric acid excretion capacity, and preparation technology. mature effect

Pending Publication Date: 2019-11-22
BEIJING HANDIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are obvious shortcomings such as large side effects in the treatment of gout by western medicine. At the same time, gout has the characteristics of recurrent attacks, and it is difficult for patients to accept long-term use of western medicine.

Method used

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  • Use of ginkgo seed ketone ester in preparation of drugs for prevention and treatment of gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0017] Example: Experimental research on ginkgo ketone ester promoting uric acid excretion in mice with hyperuricemia

[0018] 1. Test materials

[0019] 1. Test drug

[0020] Ginkgo ketone ester (GBE50) was ground with 0.5% CMC-Na before use to make a suspension of corresponding concentration; Suspension.

[0021] 2. Test animals

[0022] Animals: Clean grade Kunming mice, male, 25-30 g, 4-5 weeks old.

[0023] 3. Test reagents

[0024] Yeast extract powder, adenine, potassium oxonate, sodium carboxymethylcellulose (CMC-Na), uric acid detection kit (phosphotungstic acid method).

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to use of ginkgo seed ketone ester in preparation of drugs for prevention and treatment of gout.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the use of ginkgo ketone ester in the preparation of medicines for treating gout. Background technique [0002] Ginkgo biloba is a perennial deciduous tree of the genus Ginkgo in the Ginkgo family. Ginkgo leaves and their fruits have high medicinal value. Traditional Chinese medicine believes that ginkgo leaves are sweet, bitter, and astringent, and calm in nature. It has the effects of relieving pain, astringing the lungs and relieving asthma, astringing the intestines, relieving diarrhea, reducing turbidity and reducing lipids. It can be used clinically to treat senile dementia, vertebrobasilar insufficiency, acute cerebral infarction, chronic ischemic disease, hyperlipidemia, etc. According to reports, the research and development of ginkgo leaf preparations at this stage is one of the most successful cases in the field of medicinal plants developed by modern scie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61P19/06
CPCA61K36/16A61P19/06
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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