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Method for quickly determining content of medicinal component in zanthoxylum nitidum

A technology for rapid determination of medicinal ingredients, applied in the field of medical testing, can solve problems such as the inability to real-time detection of medicinal ingredients, and achieve the effects of being beneficial to the whole process control, reducing production and operation costs, and having strong predictive ability.

Inactive Publication Date: 2019-12-24
CHINA RESOURCES SANJIU MEDICAL & PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Therefore, the technical problem to be solved by the present invention is to overcome the defect that the high-efficiency liquid phase method in the prior art cannot realize high-efficiency, rapid, non-destructive real-time detection of the medicinal ingredients in Liangmianzhen, thereby providing a rapid determination of Liangmianzhen Method for content of Chinese medicinal ingredients

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  • Method for quickly determining content of medicinal component in zanthoxylum nitidum
  • Method for quickly determining content of medicinal component in zanthoxylum nitidum
  • Method for quickly determining content of medicinal component in zanthoxylum nitidum

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Embodiment 1

[0059] Such as figure 1 As shown, this embodiment relates to a method for rapidly determining the content of medicinal ingredients in Liangmianzhen, comprising the following steps:

[0060] S1. Select a dried sample of Liangmianzhen, pulverize it and pass it through a 60-mesh sieve, and set it aside.

[0061] S2, adopting UPLC method to measure the content of chlorinated lianmianzhen, chelerythrine, sesamin, hesperidin and magnolanine in the liangmianzhen sample in S1, the specific determination process includes the following steps:

[0062] Take 0.5 g of LMZ powder in S1, weigh it accurately, place it in a stoppered Erlenmeyer flask, accurately add 100 mL of methanol, weigh it, heat to reflux for 90 minutes, let it cool, make up the lost weight with methanol solution, shake Evenly, 0.45 μ m filter membrane filtration, promptly obtains test sample, then test sample is injected in the chromatographic column and is measured, and chromatographic column is Waters UPLC HSS T3 (1.8...

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Abstract

The invention relates to the field of medicine detection, in particular to a method for quickly determining the content of a medicinal component in zanthoxylum nitidum. The method comprises the following steps of collecting a primary near-infrared spectrum of zanthoxylum nitidum with known content of the medicinal component; building a quantitative analysis model by adopting a partial least squares method according to the primary near-infrared spectrum and the content of the medicinal component; collecting the near-infrared spectrum of to-be-detected zanthoxylum nitidum and extracting spectralinformation corresponding to the to-be-detected medicinal component under a characteristic band; inputting the spectral information into the quantitative analysis model; and obtaining the content ofthe to-be-detected medicinal component. According to the method, quick and comprehensive detection of the zanthoxylum nitidum medicinal material is achieved through introducing a near infrared spectroscopy technique, whole process control of zanthoxylum nitidum medicine production is facilitated, the production and operation cost is reduced and the quality stability of a product containing the traditional Chinese medicine zanthoxylum nitidum is improved.

Description

technical field [0001] The invention relates to the field of medical testing, in particular to a method for quickly measuring the content of medicinal ingredients in Liangmianzhen. Background technique [0002] Liangmianzhen is a traditional Chinese medicinal material, which belongs to the woody vines of the Rutaceae Zanthoxylum bungeanum, also known as Red Heart Thorn Root, Liangbeizhen, Double-faced Needle, etc. According to the "Chinese Pharmacopoeia", its function and indications are promoting blood circulation Blood stasis, promoting qi and relieving pain, dispelling wind and dredging collaterals, detoxifying and reducing swelling; it can be used for trauma, stomach pain, toothache, rheumatic arthralgia, poisonous snake bites; external treatment of burns and scalds, etc. According to modern pharmacological research, it has antibacterial and anti-inflammatory properties. , anti-tumor also has obvious effects, so double-faced acupuncture has been widely used in clinical m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/359
CPCG01N21/359
Inventor 王信宏刘晖晖郭巧生韩正洲魏伟锋马鹏岗马庆许雷张洪胜李明辉
Owner CHINA RESOURCES SANJIU MEDICAL & PHARMA
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