The invention relates to a magically effective bone pain pill which comprises following Chinese medicinal materials by weight: 20 to 40g of parched pangolin scales, 40 to 80g of agkistrodon, 20 to 40g of leeches, 20 to 40g of armadillidium vulgare, 20 to 40g of scorpion, 20 to 40g of centipede, 30 to 60g of ground beetles, 20 to 40g of lumbricus, 40 to 80g of grilled tortoise shells, 40 to 80g of grilled herbal ephedrae, 30 to 60g of colla cornus cervi, 20 to 40g of pyritum, 20 to 40g of sanguis draconis, 40 to 80g of vinegar rhizoma corydalis, 30 to 60g of asarum, 5 to 10g of radix aconiti brachypodi, 20 to 40g of radix cyathulae, 20 to 40g of huai radix achyranthis bidentatae, 20 to 40g of panax notoginseng, 30 to 60g of rhizoma gastrodiae, 10 to 20g of prepared semen strychni, 30 to 60g of rhizoma drynariae, 20 to 40g of eucommia ulmoides, 20 to 40g of radix dipsaci asperoidis, 20 to 40g of herba taxilli, 20 to 40g of radix morindae officinalis, 20 to 40g of cistanche deserticola, 20 to 40g of rhizoma cibotii, 20 to 40g of rhizoma curculiginis, 20 to 40g of herba pyrolae, 20 to 40g of olibanum, 20 to 40g of myrrh, 30 to 60g of flos carthami, 20 to 40g of radix angelicae sinensis, 40 to 80g of radix rehmanniae preparata, 20 to 40g of aristolochia mollissima hance, 20 to 40g of rhizoma homalomenae, 20 to 40g of cortex illicii, 20 to 40 parts of phryma leptostachya, 20 to 40g of radix zanthoxyli, 30 to 60g of sevenlobed yam rhizome and 40 to 80g of herba siegesbeckiae. The magically effective bone pain pill is suitable for diseases such as femoral head necrosis, mandatory spondylitis, hemiplegia, chronic waist-leg pains, sciatica, intervertebral disc herniation, spinal canal stenosis and muscular atrophy.