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Traditional Chinese medicine composition for treating porcine rotavirus disease and preparation method thereof

A technology of porcine rotavirus and composition, which is applied in the direction of antiviral agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of no specific therapeutic drugs, etc., and achieve remarkable curative effect

Inactive Publication Date: 2020-03-31
GREAT BIOLOGY PHARMA TIANJIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is currently no effective treatment for this disease, and only symptomatic treatment can be carried out, such as the use of astringent antidiarrheal agents, and the use of antibacterial drugs to prevent secondary bacterial infections, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A traditional Chinese medicine liquid for treating porcine rotavirus disease, the parts by weight of each raw material are as follows: 15 parts of bupleurum, 9 parts of baicalin, 9 parts of peony, 10 parts of pinellia, 16 parts of ginger, 9 parts of citrus aurantium, jujube 16 parts of rhubarb, 6 parts of rhubarb and 10 parts of gypsum. The preparation method is as follows: (1) crush the traditional Chinese medicine to 40 meshes, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the mixed Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil for 10 hours (3) remove the dregs by filtration, and leave the obtained filtrate for subsequent use; (4) put the dregs into the extraction tank again, add 6 times the amount of water and boil for 6 hours; Combine the extracted liquids; (6) Concentrate the extracted liquid under reduced pressure at 60°C to 20% of the original volum...

Embodiment 2

[0031] A traditional Chinese medicine liquid for treating porcine rotavirus disease, the parts by weight of each raw material are as follows: 20 parts of Bupleurum bupleurum, 12 parts of baicalin, 6 parts of peony, 12 parts of pinellia, 20 parts of ginger, 6 parts of Citrus aurantii, jujube 8 parts of rhubarb, 8 parts of rhubarb and 8 parts of gypsum. The preparation method is as follows: (1) crush the traditional Chinese medicine to 40 meshes, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the mixed Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil for 10 hours (3) remove the dregs by filtration, and leave the obtained filtrate for subsequent use; (4) put the dregs into the extraction tank again, add 6 times the amount of water and boil for 6 hours; Combine the extracted liquids; (6) Concentrate the extracted liquid under reduced pressure at 60°C to 20% of the origin...

Embodiment 3

[0033] A traditional Chinese medicine liquid for treating porcine rotavirus disease, the parts by weight of each raw material are as follows: 10 parts of bupleurum, 6 parts of baicalin, 5 parts of peony, 15 parts of pinellia, 22 parts of ginger, 8 parts of citrus aurantium, jujube 18 parts of rhubarb, 10 parts of rhubarb and 6 parts of gypsum. The preparation method is as follows: (1) crush the traditional Chinese medicine to 40 meshes, weigh according to the formula amount, and three-dimensionally mix the traditional Chinese medicine powder; (2) put the mixed Chinese medicine powder into the extraction tank, add 10 times the amount of water and boil for 10 hours (3) remove the dregs by filtration, and leave the obtained filtrate for subsequent use; (4) put the dregs into the extraction tank again, add 6 times the amount of water and boil for 6 hours; Combine the extracted liquids; (6) Concentrate the extracted liquid under reduced pressure at 60°C to 20% of the original volum...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating porcine rotavirus disease. The traditional Chinese medicine composition is prepared from radix bupleuri, scutellaria baicalensis, Chinese herbaceous peony, pinellia ternate, ginger, immature bitter orange, jujube, rheum officinale and gypsum. The traditional Chinese medicine composition can be an aqueous solution, andis prepared by the following steps: (1) crushing traditional Chinese medicines to 30-100 meshes, weighing according to the formula amount, and carrying out three-dimensional mixing to obtain traditional Chinese medicine powder; (2) putting the mixed traditional Chinese medicine powder into an extraction tank, adding 5-15 times of water, and boiling for 2-12 hours; (3) filtering to remove medicineresidues, and remaining the obtained filtrate for later use; (4) adding medicine residues into the extraction tank again, adding 5-15 times of water, and boiling for 2-12 hours; (5) filtering to remove medicine residues, and combining the obtained liquid with the first extraction liquid; and (6) concentrating the extracting solution at 30-100 DEG C under reduced pressure until the volume is 10-50% of the original volume, filtering, removing slag and filling to obtain a finished product. The formula has the effects of harmonizing Shaoyang, purging heat stagnation, harmonizing stomach, calmingadverse-rising energy, guiding dampness and relieving dysentery. When the traditional Chinese medicine composition provided by the invention is used for treating the porcine rotavirus disease, the cure rate can reach 94.12%.

Description

technical field [0001] The invention belongs to the field of traditional Chinese veterinary medicine preparations, in particular to a traditional Chinese medicine composition for treating porcine rotavirus disease and a preparation method thereof. Background technique [0002] Porcine rotavirus disease is an acute intestinal infectious disease of pigs caused by porcine rotavirus, characterized by anorexia, vomiting and diarrhea. [0003] Rotavirus mainly exists in the digestive tract of diseased pigs and infected pigs. After being excreted into the external environment with feces, it contaminates feed, drinking water, bedding and soil, etc., and then infects susceptible pigs through the digestive tract. The virus has tenacious resistance to the external environment, so that rotavirus can be repeatedly infected between adult pigs and middle-aged pigs, and takes root in pig farms for a long time. In the initial stage, the sick pigs were depressed, had a loss of appetite, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/14A61K33/06
CPCA61K33/06A61K36/233A61K36/539A61K36/65A61K36/708A61K36/71A61K36/725A61K36/752A61K36/8888A61K36/9068A61K2236/331A61K2236/39A61K2236/51A61P31/14A61K2300/00Y02A50/30
Inventor 李琳
Owner GREAT BIOLOGY PHARMA TIANJIN
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