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Electrochemical detection device based on self-assembling technology and micro-fluidic chip technology

A technology of microfluidic chip and self-assembly technology is applied in the field of electrochemical detection to achieve the effects of improving detection efficiency, reducing the use of human resources, and reducing detection costs.

Pending Publication Date: 2020-04-03
TSINGHUA UNIV
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  • Abstract
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Problems solved by technology

[0005] However, in the prior art, the combination of self-assembly technology and micro-flow technology has not been well applied to electrochemical detection technology

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  • Electrochemical detection device based on self-assembling technology and micro-fluidic chip technology

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Embodiment Construction

[0033] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments, but the protection scope of the present invention is not limited thereby.

[0034] figure 1 The electrochemical detection device 10 based on the self-assembly technology and the microfluidic chip according to the embodiment of the present invention is schematically shown.

[0035] Such as figure 1 As shown, the electrochemical detection device 10 based on self-assembly technology and microfluidic chip technology according to the embodiment of the present invention includes a sampling system 1 , a storage system 2 , a driving system 3 and a detection system 4 . Wherein, the sampling system 1 includes a sample feeder 11 and a microfluidic chip 12 . The microfluidic chip 12 includes a sample inlet 121 , an antibody channel 123 , a detection solution channel 124 and a sample channel 122 communicating with the sample inlet 121 . A control...

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Abstract

The invention provides an electrochemical detection device based on a self-assembling technology and a micro-fluidic chip technology. A sample injection system comprises a sample feeder and a micro-fluidic chip. The micro-fluidic chip comprises a sample inlet, and a sample channel, an antibody channel and a detection liquid channel which are communicated with the sample inlet. Control valves are arranged on the sample channel, the antibody channel and the detection liquid channel, and the sample feeder is connected with the sample inlet. Storage systems are respectively arranged on the antibody channel and the detection liquid channel. Driving systems are arranged on the storage systems. A detection system comprises an electrode group and an electrochemical detector connected with the electrode group, and the micro-fluidic chip is connected with the electrode group. A working electrode in the electrode group is coated with a first antibody corresponding to a sample, a freeze-dried second antibody corresponding to the sample is placed in the antibody channel, and the storage systems respectively store a second antibody dissolving solution and a detection solution. The device reducesuse of human resources, reduces the detection cost, greatly increases the detection efficiency, and realizes high-throughput detection.

Description

technical field [0001] The invention relates to the technical field of electrochemical detection, in particular to an electrochemical detection device based on self-assembly technology and microfluidic chip technology. Background technique [0002] Molecular self-assembly technology refers to the process in which molecules spontaneously form molecular assemblies with special structures and shapes under the impetus of weak forces such as hydrogen bonds, electrostatics, van der Waals forces, and hydrophobic and lipophilic forces. This technology provides people with a new method to effectively construct various structural systems from the molecular level. The self-assembly technology realized by the principle of self-assembly is spontaneous in situ, thermodynamically stable, simple in composition and independent of substrates. The influence of the shape of the material can form many advantages such as uniformity and stability, orderly arrangement of molecules, low defects, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N27/327
CPCB01L3/5027G01N27/3275B01L2300/12
Inventor 林金明
Owner TSINGHUA UNIV
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