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Application of Zishen Yutai Pills in the preparation of medicines for preventing preeclampsia

A pre-eclampsia and kidney-nourishing technology, applied in the field of medicine, to achieve the effects of inhibiting the progress of the disease, increasing the normal weight rate, and good effect

Active Publication Date: 2022-07-19
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Zishen Yutai pills have not been reported in the prevention or treatment of preeclampsia.

Method used

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  • Application of Zishen Yutai Pills in the preparation of medicines for preventing preeclampsia
  • Application of Zishen Yutai Pills in the preparation of medicines for preventing preeclampsia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 The effect of Zishen Yutai Pill on the condition of pregnant women with high risk of preeclampsia

[0022] (1) The purpose of the experiment

[0023] By comparison, the clinical curative effect of the present invention on the disease control of pregnant women with high risk of preeclampsia is analyzed and evaluated.

[0024] (2) Experimental methods and results

[0025] A total of 160 pregnant women who met the high-risk criteria for preeclampsia from 2016 to 2017 were selected and randomly divided into Zishen Yutai Pills group and placebo group according to the order of visits.

[0026] Source of patients: All cases were from outpatients of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.

[0027] Inclusion criteria:

[0028] 1. 12-20 weeks of pregnancy, singleton;

[0029] 2. At least one of the following conditions: pre-pregnancy BMI ≥ 30; diabetes; chronic hypertension; past history of placental abruption; past his...

Embodiment 2

[0044] Example 2 Effects of Zishen Yutai Pills on pregnancy outcomes of pregnant women with high risk of preeclampsia

[0045] (1) The purpose of the experiment

[0046] By comparison, the clinical curative effect of the present invention on pregnancy outcome of pregnant women with high risk of preeclampsia is analyzed and evaluated.

[0047] (2) Experimental methods and results

[0048] A total of 130 pregnant women who met the high-risk criteria for preeclampsia from 2016 to 2017 were selected and randomly divided into Zishen Yutai Pills group and placebo group according to the order of visits.

[0049] Source of patients: All cases were from outpatients of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.

[0050] Inclusion criteria:

[0051] 1. 12-20 weeks of pregnancy, singleton;

[0052] 2. At least one of the following conditions: pre-pregnancy BMI ≥ 30; diabetes; chronic hypertension; past history of placental abruption; past hi...

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PUM

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Abstract

The invention provides the application of Zishen Yutai Pill in preparing a medicine for preventing preeclampsia. Zishen Yutai Pill has a good effect on the prevention of preeclampsia, it can significantly reduce the incidence of preeclampsia in pregnant women with high risk of preeclampsia, and inhibit the progression of the disease to early-onset preeclampsia, severe preeclampsia, pregnancy hypertension; improve maternal and infant outcomes, reduce the incidence of postpartum hemorrhage, preterm birth, neonatal NICU admission, and increase the rate of normal birth weight. This indicates that Zishen Yutai Pill can improve the pregnancy outcomes of pregnant women with high risk of preeclampsia by preventing the occurrence of preeclampsia.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to the application of a Zishen Yutai Pill in preparing a medicine for preventing preeclampsia. Background technique [0002] Preeclampsia is a type of gestational hypertension (pregnancy-induced hypertension), which is a disease unique to women during pregnancy. Its clinical manifestations are mainly high blood pressure and proteinuria in women with normal blood pressure before pregnancy after 20 weeks of pregnancy. The incidence of preeclampsia is high, about 3-5%; the condition changes rapidly, and it is prone to serious complications such as HELLP syndrome, placental abruption, eclampsia, premature birth, fetal distress, etc. one of the diseases. [0003] Although the incidence of preeclampsia is high and the condition is critical, the pathogenesis is still unknown. There are currently recognized 6 points: 1. Abnormal trophoblast cells invade the myometrium; 2. Damage to vascular endoth...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P15/00A61P9/12A61P13/00A61K35/36A61K35/32
CPCA61K36/39A61K36/43A61K36/9064A61K36/804A61K36/258A61K36/185A61K35/36A61K36/704A61K36/282A61K36/746A61K36/284A61K36/344A61K35/32A61K36/815A61K36/46A61P15/00A61P9/12A61P13/00A61K2300/00
Inventor 黄秋凌庞秀霏吴亚萍尹震邹琦张春波
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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