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Application of kidney-nourishing and fetus-cultivating pill in preparing medicine for preventing preeclampsia

A preeclampsia, drug technology, applied in the field of medicine

Active Publication Date: 2020-04-07
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Zishen Yutai pills have not been reported in the prevention or treatment of preeclampsia.

Method used

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  • Application of kidney-nourishing and fetus-cultivating pill in preparing medicine for preventing preeclampsia
  • Application of kidney-nourishing and fetus-cultivating pill in preparing medicine for preventing preeclampsia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 Effect of Zishen Yutai Pills on the condition of high-risk pregnant women with preeclampsia

[0022] (1) Purpose of the experiment

[0023] Through comparison, analyze and evaluate the clinical curative effect of the present invention on condition control of pregnant women with high risk of preeclampsia.

[0024] (2) Experimental methods and results

[0025] Select 160 pregnant women who met the high-risk standard of preeclampsia in 2016-2017, and randomly divide them into the Zishen Yutai Pill group and the placebo group according to the order of treatment, and use the present invention as a control observation between the two groups after treatment.

[0026] Source of patients: All cases were from outpatients of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.

[0027] Inclusion criteria:

[0028] 1. 12-20 weeks of pregnancy, single pregnancy;

[0029] 2. Contain at least one of the following conditions: pre-pregnanc...

Embodiment 2

[0044] Example 2 Effect of Zishen Yutai Pills on Pregnancy Outcome of Preeclampsia High Risk Pregnant Women

[0045] (1) Purpose of the experiment

[0046] Through comparison, analyze and evaluate the clinical curative effect of the present invention on the pregnancy outcome of pregnant women with high risk of preeclampsia.

[0047] (2) Experimental methods and results

[0048] Select 130 pregnant women who meet the high-risk standard of preeclampsia in 2016-2017, and randomly divide them into the Zishen Yutai Pill group and the placebo group according to the order of treatment, and use the present invention as a control observation between the two groups after treatment.

[0049] Source of patients: All cases were from outpatients of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.

[0050] Inclusion criteria:

[0051] 1. 12-20 weeks of pregnancy, single pregnancy;

[0052] 2. Contain at least one of the following conditions: pre-preg...

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PUM

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Abstract

The present invention provides an application of a kidney-nourishing and fetus-cultivating pill in preparing a medicine for preventing preeclampsia. The kidney-nourishing and fetus-cultivating pill has a relatively good effect on preventing the preeclampsia, can obviously reduce preeclampsia morbidity of high-risk pregnant women in the preeclampsia, can inhibit progress of the disease into early-onset type preeclampsia, severe preeclampsia and gestational hypertension, improves maternal and infant outcome, reduces postpartum hemorrhage incidence, premature birth rate and neonatal NICU survivalrate, and increases neonatal body weight normality rate. The result shows that the kidney-nourishing and fetus-cultivating pill can improve pregnancy outcome of the pregnant women with high risk of the preeclampsia by preventing occurrence of the preeclampsia.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Zishen Yutai Pills in the preparation of medicines for preventing preeclampsia. Background technique [0002] Preeclampsia is a kind of hypertensive disorder in pregnancy (PIH). It is a disease unique to women during pregnancy. Its clinical manifestations are mainly high blood pressure and proteinuria after 20 weeks of pregnancy in women with normal blood pressure before pregnancy. The incidence of preeclampsia is high, about 3-5%; the condition changes rapidly, and it is prone to serious complications such as HELLP syndrome, placental abruption, eclampsia, premature delivery, and fetal distress. one of the diseases. [0003] Although the incidence of preeclampsia is high and the condition is critical, the pathogenesis is still unclear. At present, the following 6 points are recognized: 1. abnormal trophoblast cells invade the myometrium; 2. vascular endot...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P15/00A61P9/12A61P13/00A61K35/36A61K35/32
CPCA61K36/39A61K36/43A61K36/9064A61K36/804A61K36/258A61K36/185A61K35/36A61K36/704A61K36/282A61K36/746A61K36/284A61K36/344A61K35/32A61K36/815A61K36/46A61P15/00A61P9/12A61P13/00A61K2300/00
Inventor 黄秋凌庞秀霏吴亚萍尹震邹琦张春波
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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